A5060895832- Insect behavior and control techniques
- Insect symbiosis and bacterial influences
- Malaria Research and Control
- Mosquito-borne diseases and control
- Insect-Plant Interactions and Control
- CRISPR and Genetic Engineering
- Neurobiology and Insect Physiology Research
- Microplastics and Plastic Pollution
- Nanoparticles: synthesis and applications
- RNA Research and Splicing
University of Naples Federico II
2019-2023
Making males in a fruit fly pest The Mediterranean or Medfly ( Ceratitis capitata ) is global and highly destructive pest. Meccariello et al. identified the master gene for male sex determination on Y chromosome of named it Maleness-on-the-Y MoY (see Perspective by Makki Meller). Flies each were transformed into other genetic manipulation, crosses files generated female progeny. functionally conserved olive invasive oriental fly. This discovery has potential insect control based mass release...
In the model system for genetics, Drosophila melanogaster, sexual differentiation and male courtship behavior are controlled by sex-specific splicing of doublesex (dsx) fruitless (fru). vitro in vivo studies showed that female-specific Transformer (TRA) non-sex-specific 2 (TRA2) factors interact, forming a complex promoting dsx fru splicing. TRA/TRA2 binds to 13 nt long sequence repeats their pre-mRNAs. Mediterranean fruitfly Ceratitis capitata (Medfly), major agricultural pest, which shares...
In the last decades, colonization of Mediterranean Europe and other temperate regions by Aedes albopictus created an unprecedented nuisance problem in highly infested areas new public health threats due to vector competence species. The Sterile Insect Technique (SIT) Incompatible (IIT) are insecticide-free mosquito-control methods, relying on mass release irradiated/manipulated males, able complement existing only partially effective control tools. validation these approaches field requires...
Abstract In insects, rapidly evolving primary sex-determining signals are transduced by a conserved regulatory module producing sex-specific proteins that direct sex determination and sexual differentiation 1-4 . the agricultural pest Ceratitis capitata (medfly), Y-linked maleness factor ( M ) is thought to repress autoregulatory splicing of transformer Cctra ), which required in XX individuals establish maintain female 5,6 Despite previous attempts isolating genes using medfly whole genome,...
Abstract The colonization of Mediterranean Europe and other temperate regions by Aedes albopictus created in the last decades an unprecedented nuisance problem highly infested areas, as well a new public health threat due to species competence transmit exotic arboviruses, such dengue, chikungunya zika. Sterile Insect Technique (SIT) Incompatible (IIT) are insecticide-free mosquito-control methods relying on mass release irradiated/manipulated males which believed have potential complementing...