- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Cholesterol and Lipid Metabolism
- Peroxisome Proliferator-Activated Receptors
- Eosinophilic Disorders and Syndromes
- Fish Ecology and Management Studies
- HIV-related health complications and treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Sperm and Testicular Function
- Pneumocystis jirovecii pneumonia detection and treatment
- Animal Genetics and Reproduction
University of Pennsylvania
2008-2010
Madurai Kamaraj University
2005
Pharmacological inhibition of dietary lipid absorption induces favorable changes in serum lipoprotein levels patients that are at risk for cardiovascular disease and is considered an adjuvant or alternative treatment with HMG-CoA reductase inhibitors (statins). Here we demonstrate the feasibility identifying novel intestinal using zebrafish system. A pilot screen unbiased chemical library identified compounds inhibited processing fluorescent analogues live larvae. Secondary assays those...
A protocol for successful induction of androgenetic cloning the Buenos Aires tetra (BT), Hemigrammus caudovittatus, with contrasting gray and golden strains is described. At intensity 4.2 W/m2, UV irradiation 2.75 min totally inactivated maternal genome in eggs BT. Following activation by sperm BT, 25-min-old embryos were shocked at 41°C 2 to restore diploidy. Interestingly, hatching success haploid fry was always higher than that diploid fry, indicating enhanced homozygosity (Y2Y2) more...