Ludovico Alfarone

ORCID: 0000-0001-9702-4508
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About
Contact & Profiles
Research Areas
  • Gastric Cancer Management and Outcomes
  • Esophageal and GI Pathology
  • Colorectal Cancer Screening and Detection
  • Gastrointestinal Tumor Research and Treatment
  • Esophageal Cancer Research and Treatment
  • Metastasis and carcinoma case studies
  • Inflammatory Bowel Disease
  • Liver Disease Diagnosis and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Colorectal Cancer Surgical Treatments
  • Dysphagia Assessment and Management
  • Gastroesophageal reflux and treatments
  • AI in cancer detection
  • Radiomics and Machine Learning in Medical Imaging
  • Liver Disease and Transplantation
  • Gastrointestinal disorders and treatments
  • Genetic factors in colorectal cancer
  • Diverticular Disease and Complications
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Colorectal Cancer Treatments and Studies
  • Diagnosis and treatment of tuberculosis
  • Intraperitoneal and Appendiceal Malignancies
  • Nasal Surgery and Airway Studies
  • Reproductive System and Pregnancy
  • Liver Diseases and Immunity

IRCCS Humanitas Research Hospital
2022-2025

Humanitas University
2021-2025

Istituti di Ricovero e Cura a Carattere Scientifico
2021-2024

Hôpital Dupuytren
2024

Abstract Due to the greater risks of adverse events (AEs) and lower rate submucosal invasive cancer (SMIC), large proximal colonic polyps are frequently treated by piecemeal endoscopic mucosal resection (EMR) in West. However, this implies risk surgery radicalize non-curative case early colorectal (CRC). We evaluated procedure outcomes patients undergoing ESD for lesions at SMIC. All consecutive with SMIC splenic flexure referred a tertiary center were prospectively included from 2019 2021....

10.1055/a-2443-1609 article EN cc-by-nc-nd Endoscopy International Open 2025-01-03

Impedance and voltage of monopolar currents are directly related. By replacing air with saline solution, a change in behavior these achieved endoscopy, resulting desired coagulation effect. However, the underlying electrophysical mechanisms this effect remain poorly explained. This investigation assessed relationship between electrical parameters surrounding environment for three high-voltage commonly used therapeutic endoscopy. Six consecutive applications per setting were performed...

10.1038/s41598-024-83503-3 article EN cc-by-nc-nd Scientific Reports 2025-02-05

Achalasia is an idiopathic esophageal motility disorder, characterized by the insufficient relaxation of lower sphincter and absence peristalsis in body, leading to disabling symptoms, such as dysphagia, regurgitation, chest pain, weight loss [1]. Until a few years ago, common interventional therapeutic approaches included botulinum toxin injection, endoscopic pneumatic balloon dilation, laparoscopic Heller myotomy. Nevertheless, first options have proved be only limited efficacy, while...

10.1055/a-2258-8371 article EN cc-by Endoscopy 2024-02-22

Introduction: Inflammatory bowel disease (IBD) patients have an increased risk of developing colorectal cancer. High-risk colitis-associated neoplasia (HR-CAN) can be difficult to treat using traditional endoscopic resection methods. Aim the study is evaluate outcomes submucosal dissection (ESD) on IBD with HR-CANs. Methods: In this retrospective multicenter study, we consecutively included referred expert Italian endoscopy centers who underwent ESD or hybrid-ESD (hESD) for Main were rate...

10.1055/a-2524-3553 article EN Endoscopy 2025-01-23

Abstract Hybrid argon plasma coagulation (H-APC) is a novel technique for ablation of neoplastic Barrett's esophagus (BE), consisting in submucosal fluid injection and subsequent APC visible BE. The aim this study was to assess H-APC efficacy, safety, tolerability. We prospectively included patients undergoing at four Italian Hospitals from September 2022 March 2024. Patients with BE C3M5 maximum extent, low- or high-grade dysplasia (LGD, HGD) residual after endoscopic resection (ER) lesions...

10.1055/a-2531-8227 article EN cc-by-nc-nd Endoscopy International Open 2025-02-03

Intraprocedural bleeding due to unintentional cutting of the vessel affects both safety and efficiency third-space endoscopy may be prevented by complete coagulation before its cutting, also known as "presealing." In a prospective series, an underwater (saline-immersion) presealing technique achieved with large-tip knife appeared minimize intraprocedural bleeding, saving use cost forceps [1] [2]. Unexpectedly, when applying same small-tip rather than one, we found that effect disappeared,...

10.1055/a-2528-6414 article EN cc-by Endoscopy 2025-03-12
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