<title>Abstract</title> Why cancer is so prevalent among mammals, despite the fact that some species evolved resistance mechanisms, remains an open question. We hypothesized incidence might have been fine-tuned by evolution. Using public databases, we show with cooperative habits lower risk. By developing a novel mathematical model provide mechanistic explanation: higher of in older and less reproductive individuals can lead to counterintuitive increases population size within competitive...

El aumento global de la incidencia depresión ha generado debates sobre una posible "epidemia". En este contexto, se destaca crítica académica al estado actual práctica y el conocimiento Psiquiatría, enfocada en validez los criterios diagnósticos depresión. La Psiquiatría Precisión conjunto con Genómica Enfermedades presentan como posibles soluciones para mejorar precisión diagnóstica. nuestra investigación realizamos un análisis metodológico epistemológico las bases biológicas tal configura...

Understanding the genetic architecture of ecologically relevant adaptive traits requires contribution developmental and evolutionary biology. The time to reach age reproduction is a complex life history trait commonly known as time. In particular, in holometabolous insects that occupy ephemeral habitats, like fruit flies, impact on fitness further exaggerated. present work one first systematic studies basis time, which we also evaluate environmental variation expression trait. We analyzed...

The present study reports new presences of Drosophila suzukii (Matsumura, 1931) (Diptera: Drosophilidae) in four localities Argentina, extending its geographical range South America. Among the records, one is located Mesopotamia region eastern where flies were captured around orange and mulberry orchards. other record at Ticucho, Province Tucumán, northwest from previous record, collected an unknown host, possibly Opuntia cactus. two captures D. performed raspberries plantations Patagonia...

Previous comparative genomic studies of genes involved in olfactory behavior Drosophila focused only on particular gene families such as odorant receptor and/or binding proteins. However, has a complex genetic architecture that is orchestrated by many interacting genes. In this paper, we present study including an extended set known to affect behavior. We took advantage the recent burst whole genome sequences and development powerful statistical tools analyze data test evolutionary...

Odour-guided behaviour is a quantitative trait determined by many genes that are sensitive to gene-environment interactions. Different natural populations likely experience different selection pressures on the genetic underpinnings of chemosensory behaviour. However, few studies have reported comparisons basis olfactory in geographically distinct populations. We generated isofemale lines Drosophila melanogaster from six Argentina and measured larval adult responses benzaldehyde. There was...

Background Previously, we have shown there is clinal variation for egg-to-adult developmental time along geographic gradients in Drosophila melanogaster. Further, also identified mutations genes involved metabolic and neurogenic pathways that affect development (heterochronic genes). However, do not know whether these loci natural populations. Methodology/Principal Findings Here, constructed second chromosome substitution lines from populations of melanogaster an altitudinal cline, measured...

Developmental conservation among related species is a common generalization known as von Baer's third law and implies that early stages of development are the most refractory to change. The "hourglass model" an alternative view proposes middle constrained during development. To investigate this issue, we undertook genomic approach provide insights into how natural selection operates on genes expressed first 24 h Drosophila ontogeny in six melanogaster group for which whole genome sequences...

El trastorno por déficit de atención e hiperactividad (TDAH) es el mental considerado más frecuente en la infancia. Si bien su diagnóstico manual psiquiatría hoy utilizado mundo, Diagnostic and statistical of disorders (DSM-5), se basa los comportamientos desatención, impulsividad, encuentran numerosos intentos describir las bases biológicas del para usarlos con fines y como marcadores riesgo. En este trabajo analizamos críticamente validez estudios asociados a búsqueda genéticos TDAH....

Zaprionus indianus is a species of fl y native to the Afrotropical biogeographic region, which around twenty years ago invaded American continent.Several studies have shown that local adaptation and phenotypic plasticity an invasive in its range could favour colonization new environments.Zaprionus holometabolo us generalist polyphagous breeds feeds on fruits several different species, constitute environments.In this context, we performed comparative analysis morphological life history traits...

Abstract It has been demonstrated that phenotypic plasticity and genotype by environment interaction are important for coping with new heterogeneous environments during invasions. Zaprionus indianus Gupta (Diptera: Drosophilidae) is an Afrotropical invasive fly species introduced to the South American continent in 1999. This generalist polyphagous, since it develops feeds several different fruit species. These characteristics of Z. suggest may be this invasion process. In sense, our aim was...

The notion of symbiogenesis proposed by Lynn Margulis refers to the establishment persistent symbiosis that originates new biological entities. proposal an evolutionary relevance has been framed in a more general discussion about need revise and extend Synthetic Theory Evolution. In this context, several authors have presented as important mechanism evolution. However, epistemological status is still subject debate. Thus, central question paper whether only generate novelty or also change,...

Zaprionus indianus Gupta is an invasive pest species that has colonized the American continent in last 20 years. This a polyphagous with Drosophila melanogaster Meigen and D. simulans Sturtevant utilized wide variety of fruits as breeding feeding resources. In present study we quantified relative abundance these adult emerged samples collected from various hosts (commercial fruits) different localities northern Argentina. We detected overlapping rearing resources between analyzed although,...

<title>Abstract</title> The development of cancer has been traditionally seen as a ‘side-effect’ other processes under selection or conceived selectively neutral since tends to occur after reproduction1. Although some mammals present molecular mechanisms that confer resistance developing tumors, is widely distributed throughout the tree life2–4. In fact, ecological systems can experience counterintuitive increases in population size, phenomenon known hydra effect, when subpopulation exhibits...

La epigenética como campo disciplinar de consolidación reciente, al estudiar lo humano trajo consigo promesas superación del determinismo y la reducción explicativa propios corriente gen-centrista genética. Sin embargo, analizar las características epistemológicas abordaje epigenético humano, dichas parecen no haberse cumplido. El borramiento límite naturaleza/crianza habilita un tipo particular cuyo alcance en términos biopolíticos se inscribe el control los comportamientos posibles. Se...

Abstract Organisms utilize environmental cues to deal with heterogeneous environments. In this sense, behaviours that mediate interactions between organisms and their environment are complex traits, especially sensitive conditions. animals, olfaction is a critical sensory system allows them acquire chemical information from the environment. The genetic basis physiological mechanisms of olfactory D rosophila melanogaster M eigen ( iptera: rosophilidae) well known, but effects ecological...

Resumen El trastorno por déficit de atención e hiperactividad (TDAH) se encuentra entre los trastornos psiquiátricos infantiles más prevalentes en la actualidad y, desde áreas biomédicas y neurobiológicas, considera que presenta una base biológica. En el presente trabajo analizarán, aproximación filosófica, discursos despliegan dichas investigaciones con objetivo detectar clarificar diversos aspectos fenoménicos, teóricos ontológicos le subyacen. términos generales, hemos encontrado...