A5006436252- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- 3D Printing in Biomedical Research
- Nanoparticles: synthesis and applications
- RNA Interference and Gene Delivery
- Wound Healing and Treatments
- Tissue Engineering and Regenerative Medicine
- Advanced Sensor and Energy Harvesting Materials
- Bacteriophages and microbial interactions
- Enzyme Structure and Function
- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Electrohydrodynamics and Fluid Dynamics
- Polymer Nanocomposite Synthesis and Irradiation
- Antimicrobial Resistance in Staphylococcus
- Nanotechnology research and applications
- biodegradable polymer synthesis and properties
- Bacterial Genetics and Biotechnology
- Surgical Sutures and Adhesives
- Nerve injury and regeneration
- Extracellular vesicles in disease
- Biochemical and Molecular Research
- Cancer therapeutics and mechanisms
- Silk-based biomaterials and applications
National Centre for Cell Science
2020-2025
Centre for DNA Fingerprinting and Diagnostics
2025
Defence Institute of Advanced Technology
2015-2021
Nano-sized materials have been an important tool in basic and applied sciences. A novel, low cost, green reproducible bacteria, Staphylococcus aureus mediated biosynthesis of titanium dioxide nanoparticles (TiO2 NPs) was reported the present study. Initial conformational studies were done using UV-visible spectroscopy confirmed synthesis TiO2 NPs broth. The detailed characterization TiO2NPs carried out SEM, XRD, FTIR Raman spectroscopy. From it that sample showed smooth spherical with...
In this study, poly(ε-caprolactone) (PCL) has been blended with a more hydrophilic poly(ethylene glycol) (PEG) and biocompatible block-co-polymer: poly(L-lactide-co-ε-caprolactone-co-glycolide) (PLCG) in order to improve hydrophilicity, biocompatibility biodegradability of PCL. PCL the blend solutions were subjected electrospinning produce nanofiber scaffolds by addition only 1 wt% PEG PLCG either singly or combination retain mechanical properties scaffolds. PCL-PEG-PLCG ternary two binary...
Emblica officinalis fruit extract has been incorporated into polymer nanofiber scaffold and the resulting showed excellent antibacterial anti-proliferative properties.
Controlled drug release and antibacterial properties of electrospun nanofiber depend on slow molecules to the targeted area by diffusion embedded in nanofiber. In present study, chloramphenicol (CAP), an has been incorporated poly(e-caprolactone) (PCL) nanofibers weight content 5–20 wt% electrospinning. It was found that fiber diameter hydrophilic nature increased with increase CAP content. The latter phenomenon is expected facilitate biocompatibility scaffolds. scaffolds showed excellent...
In the bone tissue engineering composite scaffolds with osteogenic potential are emerging as new tool. Here, we investigated graphene (GP), oxide (GO) and Cissus quadrangularis (CQ) callus extract for their spontaneous osteoinductive potential. Electrospun poly ε-caprolactone (PCL) sheets were painted varying combination GP, GO CQ solutions ink. The prepared PCL-GO, PCL-GO-CQ, PCL-GP PCL-GP-CQ characterized physical, mechanical biological properties. Addition of GO, GO-CQ GP-CQ to PCL...
Bacterial sigma (σ) factors are an essential component of RNA polymerase.It determines the promoter selectivity.Alternative σ play key roles in coordinating gene transcription during various environmental stresses, nutrient starvation responses and morphological development.The extra cytoplasmic function (ECF) small regulatory proteins that quite divergent sequence relative to most other factors.In many bacteria with complex genome, contain multiple ECF these regulators often outnumber all...
The present study investigates the effect of poly(ethylene glycol) (PEG) addition on physico-chemical, thermo-mechanical, drug release, antibacterial and biocompatible properties poly(ε-caprolactone) (PCL)-chloramphenicol (CAP) electrospun nanofiber scaffolds. Incorporation PEG imparted enhanced hydrophilicity, crystallinity, glass transition temperature cell growth ability reduced cytotoxicity in PCL. In vitro release studies reveal that PCL-CAP facilitated well-defined kinetics profiles...
Staphylococcus aureus is an important human and animal pathogen that causes a wide range of infections. The prevalence multidrug-resistant S. strains in both hospital community settings makes it imperative to characterize new drug targets combat In this context, enzymes involved NAD metabolism synthesis are significant as central player several cellular processes. synthetase catalyzes the last step biosynthesis nicotinamide adenine dinucleotide, making crucial intermediate enzyme linked...
In recent years, Cellulose Acetate (CA) electrospun nanofiber membranes gained a tremendous interest in the polymer research due it broad application. CA is modified natural produced by acetylation of cellulose, which one most abundant, low cost renewable polymers