- Renal Diseases and Glomerulopathies
- Systemic Lupus Erythematosus Research
- Vasculitis and related conditions
- Renal Transplantation Outcomes and Treatments
- Cytomegalovirus and herpesvirus research
- Chronic Lymphocytic Leukemia Research
- Parathyroid Disorders and Treatments
- Inflammatory Bowel Disease
- Magnesium in Health and Disease
- Vitamin K Research Studies
- Organ Transplantation Techniques and Outcomes
- Dialysis and Renal Disease Management
- Immunodeficiency and Autoimmune Disorders
- Advanced battery technologies research
- Atherosclerosis and Cardiovascular Diseases
- Bacterial Infections and Vaccines
- Coenzyme Q10 studies and effects
- Viral Infections and Immunology Research
- SARS-CoV-2 and COVID-19 Research
Duchess of Kent Children's Hospital
2022-2024
Age-specific incidence of acute myocarditis/pericarditis in adolescents following Comirnaty vaccination Asia is lacking. This study aimed to the clinical characteristics and among Hong Kong vaccination.This a population cohort that monitored adverse events immunization through pharmacovigilance system for coronavirus disease 2019 (COVID-19) vaccines. All aged between 12 17 years were under COVID-19 vaccine event response evaluation program. The overall analyzed.Between 14 June 2021 4...
Long-term data pertaining to childhood-onset lupus nephritis (cLN) remain extremely scarce.We conducted a retrospective cohort study of biopsy-proven cLN with onset age <18 years diagnosed from 2001 2020 ascertain the long-term patient and kidney survival rates, incidence advanced chronic disease (CKD) (estimated glomerular filtration rate [eGFR] <60 ml/min per 1.73 m2).A total 92 subjects (78 female; 13.7 ± 3.3 years; all Chinese) were included, follow-up duration 10.3 (interquartile range,...
There is little data on renal relapse in childhood-onset LN (cLN). We investigate the incidence, predictive factors and outcomes related to relapse.
Abstract A subgroup of children with frequently-relapsing, steroid-dependent nephrotic syndrome relapse during B-cell depletion after rituximab. 15-year-old boy focal segmental glomerulosclerosis became rituximab-refractory 5 courses treatments, a relapse-free period shortened to 1 month. Circulating total and memory B-cells were undetectable at the time relapse. single infusion obinutuzumab sustained remission up last follow-up 18 months. There was persistent hypogammaglobulinemia but no...
ABSTRACT Aim To review the clinical characteristics and long‐term outcomes of paediatric kidney transplants in Hong Kong. Method A retrospective cohort study was carried out on all transplant recipients managed Paediatric Nephrology Centre Kong from 2009 to 2020. All were under 21 at time transplant, with a minimal follow‐up period 2 years. Results Sixty‐one patients (57.4% male; median age 13 years, IQR: 8.9–17.8) followed for 6.4 years (IQR 4.3–9.6). The commonest causes failure congenital...
<title>Abstract</title> <bold>Background: </bold>This study aimed to determine the clinical significance of renal vascular lesions (RVLs) in childhood-onset lupus nephritis (cLN). <bold>Methods: </bold>We retrospectively reviewed all children with biopsy-proven cLN between 2004-2020 evaluate prevalence RVLs on kidney biopsy and its associated factors long-term outcomes. The composite outcome was defined as advanced chronic disease (CKD) stage 3-5, end-stage (ESKD) death. <bold>Results:...