Leslie Ying

ORCID: 0000-0001-9801-1362
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About
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Research Areas
  • Advanced MRI Techniques and Applications
  • Medical Imaging Techniques and Applications
  • Sparse and Compressive Sensing Techniques
  • Photoacoustic and Ultrasonic Imaging
  • Advanced Neuroimaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Atomic and Subatomic Physics Research
  • MRI in cancer diagnosis
  • Image and Signal Denoising Methods
  • Advanced NMR Techniques and Applications
  • Advanced Fluorescence Microscopy Techniques
  • Medical Image Segmentation Techniques
  • Advanced X-ray and CT Imaging
  • Wireless Body Area Networks
  • Cardiac Imaging and Diagnostics
  • Cell Image Analysis Techniques
  • NMR spectroscopy and applications
  • Optical Imaging and Spectroscopy Techniques
  • Thermography and Photoacoustic Techniques
  • Ultrasound Imaging and Elastography
  • Advanced Electron Microscopy Techniques and Applications
  • AI in cancer detection
  • Blind Source Separation Techniques
  • Advanced X-ray Imaging Techniques
  • Microwave Imaging and Scattering Analysis

University at Buffalo, State University of New York
2015-2024

King Abdullah University of Science and Technology
2023

University of Michigan
2021

Tokyo Institute of Technology
2021

Dalle Molle Institute for Artificial Intelligence Research
2021

University of Applied Sciences and Arts of Southern Switzerland
2021

Purdue University West Lafayette
2021

University of Arkansas at Fayetteville
2021

Geisinger Health System
2021

Fourth Hospital of Inner Mongolia
2020

This paper proposes a deep learning approach for accelerating magnetic resonance imaging (MRI) using large number of existing high quality MR images as the training datasets. An off-line convolutional neural network is designed and trained to identify mapping relationship between obtained from zero-filled fully-sampled k-space data. The not only capable restoring fine structures details but also compatible with online constrained reconstruction methods. Experimental results on real data have...

10.1109/isbi.2016.7493320 article EN 2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI) 2016-04-01

Abstract Both parallel MRI and compressed sensing (CS) are emerging techniques to accelerate conventional by reducing the number of acquired data. The combination CS for further acceleration is great interest. In this paper, we propose a novel method combine sensitivity encoding (SENSE), one standard methods MRI, rapid MR imaging (SparseMRI), recently proposed applying in with Cartesian trajectories. method, named CS‐SENSE, sequentially reconstructs set aliased reduced‐field‐of‐view images...

10.1002/mrm.22161 article EN Magnetic Resonance in Medicine 2009-09-25

Image reconstruction from undersampled k-space data has been playing an important role in fast magnetic resonance imaging (MRI). Recently, deep learning demonstrated tremendous success various fields and also shown potential significantly accelerating MRI with fewer measurements. This article provides overview of deep-learning-based image methods for MRI. Two types deep-learningbased approaches are reviewed, those that based on unrolled algorithms not, the main structures both explained....

10.1109/msp.2019.2950557 article EN IEEE Signal Processing Magazine 2020-01-01

Abstract Parallel magnetic resonance imaging (pMRI) using multichannel receiver coils has emerged as an effective tool to reduce time in various applications. However, the issue of accurate estimation coil sensitivities not been fully addressed, which limits level speed enhancement achievable with technology. The self‐calibrating (SC) technique for sensitivity extraction well accepted, especially dynamic imaging, and complements common calibration that uses a separate scan. existing method...

10.1002/mrm.21245 article EN Magnetic Resonance in Medicine 2007-05-29

Abstract: This article presents a Beamlet transform-based approach to automatically detect and classify pavement cracks in digital images. The proposed method uses distress image enhancement algorithm correct the nonuniform background illumination by calculating multiplicative factors that eliminate lighting variation. To extract linear features such as surface from images, is partitioned into small windows applied. crack segments are then linked together classified four types: vertical,...

10.1111/j.1467-8667.2010.00674.x article EN Computer-Aided Civil and Infrastructure Engineering 2010-06-09

In dynamic cardiac cine magnetic resonance imaging, the spatiotemporal resolution is limited by low imaging speed. Compressed sensing (CS) theory has been applied to improve speed and thus resolution. this paper, we propose a novel technique that employs patch-based 3-D dictionary for sparse representations of image sequence in CS framework. Specifically, divided into overlapping patches along both spatial temporal directions. The used provide flexible expressions these patches. underlying...

10.1109/tbme.2013.2294939 article EN IEEE Transactions on Biomedical Engineering 2014-01-31

Dynamic MR image reconstruction from incomplete k-space data has generated great research interest due to its capability in reducing scan time. Nevertheless, the problem is still challenging ill-posed nature. Most existing methods either suffer long iterative time or explore limited prior knowledge. This paper proposes a dynamic imaging method with both and spatial knowledge integrated via multi-supervised network training, dubbed as DIMENSION. Specifically, DIMENSION architecture consists...

10.1002/nbm.4131 article EN NMR in Biomedicine 2019-09-04

Image recovery from undersampled data has always been challenging due to its implicit ill-posed nature but becomes fascinating with the emerging compressed sensing (CS) theory. This paper proposes a novel gradient based dictionary learning method for image recovery, which effectively integrates popular total variation (TV) and technique into same framework. Specifically, we first train dictionaries horizontal vertical gradients of then reconstruct desired using sparse representations both...

10.1109/tip.2013.2277798 article EN IEEE Transactions on Image Processing 2013-09-25

While many low rank and sparsity-based approaches have been developed for accelerated dynamic magnetic resonance imaging (dMRI), they all use rankness or sparsity in input space, overlooking the intrinsic nonlinear correlation most dMRI data. In this paper, we propose a kernel-based framework to allow manifold models reconstruction from sub-Nyquist Within framework, existing algorithms can be extended kernel with models. particular, novel algorithm low-rank model generalizing conventional...

10.1109/tmi.2017.2723871 article EN publisher-specific-oa IEEE Transactions on Medical Imaging 2017-07-05

Compact, lightweight, and on-chip spectrometers are required to develop portable handheld sensing analysis applications. However, the performance of these miniaturized systems is usually much lower than their benchtop laboratory counterparts due oversimplified optical architectures. Here, we a compact plasmonic "rainbow" chip for rapid, accurate dual-functional spectroscopic that can surpass conventional under selected conditions. The nanostructure consists one-dimensional or two-dimensional...

10.1038/s41467-023-37628-0 article EN cc-by Nature Communications 2023-04-05

Abstract Compressed sensing (CS) has been used in dynamic cardiac MRI to reduce the data acquisition time. The sparseness of image series spatial‐ and temporal‐frequency ( x‐f ) domain exploited existing works. In this article, we propose a new k ‐ t iterative support detection ISD) method improve CS reconstruction for by incorporating additional information on space based theory with partially known support. proposed uses an procedure alternating between space. At each iteration, truncated...

10.1002/mrm.23197 article EN Magnetic Resonance in Medicine 2011-11-23

Abstract In sensitivity encoding reconstruction, the issue of ill conditioning becomes serious and thus signal-to-noise ratio poor when a large acceleration factor is employed. Total variation (TV) regularization has been used to address this shown better preserve sharp edges than Tikhonov but may cause blocky effect. article, we study nonlocal TV for noise suppression in reconstruction. The method extends conventional norm version by introducing weighted gradient function calculated from...

10.1002/mrm.22736 article EN Magnetic Resonance in Medicine 2010-12-16

Abstract GRAPPA linearly combines the undersampled k ‐space signals to estimate missing where coefficients are obtained by fitting some auto‐calibration (ACS) sampled with Nyquist rate based on shift‐invariant property. At high acceleration factors, reconstruction can suffer from a level of noise even large number signals. In this work, we propose nonlinear method improve GRAPPA. The is so‐called kernel which widely used in machine learning. Specifically, mapped through transform...

10.1002/mrm.23279 article EN Magnetic Resonance in Medicine 2011-12-12

The integration of compressed sensing and parallel imaging (CS-PI) has shown an increased popularity in recent years to accelerate magnetic resonance (MR) imaging. Among them, calibration-free techniques have presented encouraging performances due its capability robustly handling the sensitivity information. Unfortunately, existing methods only explored joint-sparsity with direct analysis transform projections. To further exploit improve reconstruction accuracy, this paper proposes Learn...

10.1109/tmi.2017.2746086 article EN IEEE Transactions on Medical Imaging 2017-08-28

Deep learning methods have achieved attractive performance in dynamic MR cine imaging. However, most of these are driven only by the sparse prior images, while important low-rank (LR) images is not explored, which may limit further improvements reconstruction. In this paper, a learned singular value thresholding (Learned-SVT) operator proposed to explore priors imaging obtain improved reconstruction results. particular, we put forward model-based unrolling and network for imaging, dubbed as...

10.1109/tmi.2021.3096218 article EN IEEE Transactions on Medical Imaging 2021-07-12

Purpose: To propose a deep learning-based reconstruction framework for ultrafast and robust diffusion tensor imaging fiber tractography. Methods: We SuperDTI to learn the nonlinear relationship between diffusion-weighted images (DWIs) corresponding tensor-derived quantitative maps as well Super DTI bypasses fitting procedure, which is known be highly susceptible noise motion in DWIs. The network trained tested using datasets from Human Connectome Project patients with ischemic stroke....

10.1002/mrm.28937 article EN Magnetic Resonance in Medicine 2021-07-26

Abstract In parallel imaging, the signal‐to‐noise ratio (SNR) of sensitivity encoding (SENSE) reconstruction is usually degraded by ill‐conditioning problem, which becomes especially serious at large acceleration factors. Existing regularization methods have been shown to alleviate problem. However, they suffer from image artifacts high factors due data inconsistency resulting heavy regularization. this paper, we propose Bregman iteration for SENSE Unlike existing where function fixed,...

10.1002/mrm.21799 article EN Magnetic Resonance in Medicine 2008-12-18

Compressed sensing (CS) has recently drawn great attentions in the MRI research community. The most desirable property of CS application is that it allows sampling k-space well below Nyquist rate, while still being able to reconstruct image if certain conditions are satisfied. Recent work successfully applied reduce scanning time conventional Fourier imaging. In this paper, parallel imaging, a fast imaging technique, investigated achieve an even higher speed. scheme for incoherence discussed...

10.1109/itab.2008.4570588 article EN 2008-05-01

Compressed sensing (CS) can recover sparse signals from undersampled measurements.In this work, we have developed an advanced CS framework for photoacoustic computed tomography (PACT).During the reconstruction, a small part of nonzero signals' locations in transformed domain is used as partially known support (PKS).PACT reconstructions been performed with under-sampled vivo image data human hands and rat.Compared to PACT basic CS, CS-PKS using fewer ultrasonic transducer elements improve...

10.1364/oe.20.016510 article EN cc-by Optics Express 2012-07-06

Purpose This work is to develop a novel image reconstruction method from highly undersampled multichannel acquisition reduce the scan time of exponential parameterization T2 relaxation. Theory and Methods On top low‐rank joint‐sparsity constraints, we propose exploit linear predictability decay further improve T2‐weighted images acquisitions. Specifically, exact rank prior (i.e., number non‐zero singular values) adopted enforce spatiotemporal low rankness, while mixed L2–L1 norm wavelet...

10.1002/mrm.26083 article EN Magnetic Resonance in Medicine 2016-01-13

In positron emission tomography (PET) image reconstruction, the Bayesian framework with various regularization terms has been implemented to constrain radio tracer distribution. Varying regularizing weight of a maximum posteriori (MAP) algorithm specifies lower bound tradeoff between variance and spatial resolution measured from reconstructed images. The purpose this paper is build patch-based enhancement scheme reduce size unachievable region below thus quantitatively improve PET imaging....

10.1109/tmi.2018.2803681 article EN publisher-specific-oa IEEE Transactions on Medical Imaging 2018-02-07
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