Sebastian Botero

ORCID: 0000-0001-9807-1090
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About
Contact & Profiles
Research Areas
  • Selenium in Biological Systems
  • Trace Elements in Health
  • Viral Infections and Immunology Research
  • T-cell and Retrovirus Studies
  • International Relations in Latin America
  • Animal Disease Management and Epidemiology
  • Viral gastroenteritis research and epidemiology
  • RNA regulation and disease
  • Plant Pathogens and Fungal Diseases
  • Moringa oleifera research and applications
  • Animal Nutrition and Physiology
  • Veterinary medicine and infectious diseases
  • Whipple's Disease and Interleukins
  • Public Health and Environmental Issues
  • Immune Cell Function and Interaction
  • COVID-19 Pandemic Impacts
  • Fungal Infections and Studies
  • Salmonella and Campylobacter epidemiology

Universidad de Manizales
2020

Beltsville Human Nutrition Research Center
2006-2011

Agricultural Research Service
2004-2011

United States Department of Agriculture
2004-2011

National Institute of Allergy and Infectious Diseases
2011

Bhabha Atomic Research Centre
2007

Durante las últimas décadas, el mundo se ha expuesto a una serie de amenazas por brotes virales emergentes diferente índole, los cuales, sólo al estudiarlos en detalle, surge la posibilidad
 comprender su verdadero impacto, no forma inmediata, si también, largo plazo.
 Recientemente, 12 diciembre 2019, Comisión Municipal Salud Wuhan, República Popular China, hizo público un reporte 27 casos humanos quienes cursaron con neumonía viral, cuales 7 pacientes encontraban condiciones...

10.35663/amp.2020.371.909 article ES cc-by ACTA MEDICA PERUANA 2020-03-18

Pigs infected with Ascaris suum or controls were given 100 microg (low-dose) 1,000 (high-dose) all-trans retinoic acid (ATRA)/kg body weight in corn oil alone per os on days after inoculation (DAI) -1, +1, and +3 infective eggs. Treatment ATRA increased interleukin 4 (IL4) IL12p70 plasma of pigs at 7 DAI augmented bronchoalveolar lavage (BAL) eosinophilia observed 14 DAI. To explore potential molecular mechanisms underlying these observations, a quantitative real-time reverse transcription...

10.1128/iai.00827-07 article EN cc-by Infection and Immunity 2009-03-31

The pathogenesis of a Citrobacter rodentium infection was evaluated in mice fed diets with single deficiency either selenium or vitamin E double both and compared to on nutritionally adequate diets. Mice the selenium- E-deficient diet for 6 weeks had increased loads C. colon spleen, which were not observed singly deficient diet. Infected doubly crypt hyperplasia an influx infiltrating cells along gross changes architecture, including ulceration denuding epithelial layer. Cytokine chemokine...

10.1128/iai.01017-10 article EN Infection and Immunity 2011-01-19

Bovine enteroviruses are members of the family Picornaviridae , genus Enterovirus . Whilst little is known about their pathogenic potential, they apparently endemic in some cattle and environments. Only one two current serotypes has been sequenced completely. In this report, entire genome sequences bovine enterovirus 2 (BEV-2) strain PS87 a recent isolate from an endemically infected herd Maryland, USA (Wye3A) presented. The clearly segregated phylogenetically with representing BEV-2...

10.1099/vir.0.80159-0 article EN Journal of General Virology 2004-10-13

Previous studies have shown that mice maintained on diets deficient in selenium and/or vitamin E showed a delayed clearance of nematode parasite, Heligmosomoides polygyrus, from the intestine independent IL-4 and IL-13. Changes oxidative stress presumably altered intestinal function. In this study Citrobacter rodentium (CR) was used as model enteric bacterial infection to determine if nutritionally-induced would alter CR-induced pathogenesis. Like E. coli infections humans, CR induces...

10.1096/fasebj.21.5.a376-b article EN other-oa The FASEB Journal 2007-04-01

Mice fed a diet deficient in Se show reduced resistance to secondary infection with H. polygyrus. IL-4 and IL-13 dependent increases intestinal smooth muscle hyper-contractility decreased glucose absorption correlate expulsion of the adult worm following challenge infection. Selenium deficiency, however, does not affect local gene expression for or associated changes epithelial cell function. This suggests another protective mechanism compromised by deficiency. Parasitic polygyrus larvae...

10.1096/fasebj.21.5.a63-a article EN other-oa The FASEB Journal 2007-04-01

Both selenium and vitamin E are important antioxidant nutrients. Previous studies have demonstrated that passage of coxsackievirus B3 (CVB3) through or deficient mice can rapidly select for more pathogenic variants. It has been proposed oxidative stress may lead to enhanced rates viral evolution. Copper deficiency is also associated with increased levels stress. Thus, we were interested in determining if copper would virulence pathology infected CVB3. Pregnant Swiss outbred fed a diet...

10.1096/fasebj.20.4.a554-a article EN The FASEB Journal 2006-03-01

As time flies, every country must face the unknown regarding balance between social distance measures and reopening economy safely. Some countries are windows to future, but experiences of our neighbors best suited anticipate some aspects reality in a few weeks. hard-hit areas United States, where disparities explain huge inter-racial gap mortality from COVID-19, clear examples how inequality can divide trajectories different population groups same country. Furthermore, gruesome images...

10.17151/hpsal.2020.25.2.2 article EN cc-by Deleted Journal 2020-07-01
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