A5017494139- Microfluidic and Capillary Electrophoresis Applications
- Analytical Chemistry and Chromatography
- Innovative Microfluidic and Catalytic Techniques Innovation
- Various Chemistry Research Topics
- Chromatography in Natural Products
- Mass Spectrometry Techniques and Applications
- Advanced Chemical Sensor Technologies
- Protein purification and stability
- Metabolomics and Mass Spectrometry Studies
- 3D Printing in Biomedical Research
- Analytical chemistry methods development
- Analytical Methods in Pharmaceuticals
- Genetics, Bioinformatics, and Biomedical Research
- Electrowetting and Microfluidic Technologies
- Scientific Computing and Data Management
- Fluid dynamics and aerodynamics studies
- Mobile Learning in Education
- Online Learning and Analytics
- Augmented Reality Applications
- Electrohydrodynamics and Fluid Dynamics
- Protein Structure and Dynamics
- Heat and Mass Transfer in Porous Media
- Traumatic Brain Injury Research
- Pesticide Residue Analysis and Safety
- Innovative Teaching Methods
Rowan University
2017-2024
University of Michigan
2015-2020
Ann Arbor Center for Independent Living
2018-2020
University of North Carolina at Chapel Hill
2012-2015
Many research and teaching laboratories rely on USB data acquisition devices to collect voltage signals from instrumentation. However, these can be cost-prohibitive (especially when large numbers are needed for laboratories) require software developed operation. In this article, we describe the development use of an open-source device (with 16-bit resolution) built using simple electronic components Arduino Uno that costs under $50. Additionally, written in Python is included so acquired...
We derive a quantitative relationship between the bed morphology and chromatographic separation efficiency of capillary columns packed with sub-2 μm particles, covering inner diameters from 10 to 75 μm. Our study focuses on wall effects their impact band broadening at increasing column-to-particle diameter (aspect) ratios. approach these complex by morphological analysis reconstructed column segments composed several thousand particles that were imaged confocal laser scanning microscopy....
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTHigh-Throughput and Ultrafast Liquid ChromatographyAlexander S. KaplitzAlexander KaplitzDepartment of Chemistry & Biochemistry, Rowan University, Glassboro, New Jersey 08028, United StatesMore by Alexander KaplitzView Biography, Glenn A. KresgeGlenn KresgeDepartment KresgeView Benjamin SeloverBenjamin SeloverDepartment SeloverView Leah HorvatLeah HorvatDepartment HorvatView Edward G. FranklinEdward FranklinRegis Technologies, Inc., Morton Grove,...
Instruction on the design of analytical instrumentation is a critical component chemistry curriculum. To simplify this process and enable students to directly see how instruments that are in their own laboratory setting work, use augmented reality technology can be implemented. In report, HP Reveal platform was used create digital overlays triggered when view an instrument through smartphone camera. From here, further information components operation presented students. demonstrate...
Abstract A newly developed portable capillary liquid chromatograph was investigated for the separation of various pharmaceutical and illicit drug compounds. The system consists two high‐pressure syringe pumps capable delivering capillary‐scale flow rates at pressures up to 10 000 psi. Capillary chromatography columns packed with sub‐2 μm particles are housed in cartridges that can be inserted into easily connected through fluidic contact points by simply applying a specific, predetermined...
Online student-response systems provide instructors with an easy-to-use tool to instantly evaluate student comprehension. For comprehensive content review, turning this evaluation into a competitive game where students can compete against each other was found be helpful and enjoyable for participating students. One specific online resource, Kahoot!, provides the opportunity crowd-sourced quizzes generated, potentially enabling creation of open-source repository review questions ACS...
The cycle time of a standard liquid chromatography (LC) system is the sum for chromatographic run and autosampler injection sequence. Although LC separation times in 1–10 s range have been demonstrated, sequences are commonly >15 s, limiting throughput possible with separations. Further, such separations performed on relatively large bore columns requiring flow rates ≥5 mL/min, thus generating volumes mobile phase waste when used scale screening increasing difficulty interfacing to mass...
As column volumes continue to decrease, extra-column band broadening has become an increasingly important consideration when determining performance. Combined contributions due the injector and connecting tubing in a capillary LC system were measured found be larger than expected by Taylor-Aris theory. Variance from sigma-type tau-type was isolated eluted peaks using Foley-Dorsey Exponentially Modified Gaussian peak fitting model confirmed with computational fluid dynamics. It that main...
Here protein cross-linking capillary electrophoresis is demonstrated for a wide range of protein–protein interactions including weak and multimeric oligomers.
A metal tube-in-manifold packed bed capillary column device, designed to overcome common limitations associated with LC separations, is described. Experimental results of initial packing tests sub-3 μm core-shell particles demonstrated efficiencies greater than 47,000 plates/m for a separation performed using the device. Computational fluid dynamics (CFD) modeling multicomponent used this work was validated against experimental and optimized model able effectively predict component peak...
High-performance liquid chromatography is one of the primary techniques covered in undergraduate analytical chemistry curriculum. This technology report describes use a portable capillary-scale instrument that can provide similar performance to benchtop but generates less solvent waste and enables operation nonlaboratory settings. Comparisons between two types were made for single-standard calibration analysis caffeine diet soda aspirin content over-the-counter tablets, with relative percent...
A microfluidic device for automated BzCl derivatization and application to<italic>in vivo</italic>neurochemical monitoring using LC-MS/MS.