- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- 3D Printing in Biomedical Research
- Wound Healing and Treatments
- Bone Tissue Engineering Materials
- Additive Manufacturing and 3D Printing Technologies
- Periodontal Regeneration and Treatments
- Silk-based biomaterials and applications
- Copper-based nanomaterials and applications
- MicroRNA in disease regulation
- Mesenchymal stem cell research
- Magnesium Oxide Properties and Applications
- Graphene and Nanomaterials Applications
- Advanced Photocatalysis Techniques
- Diabetic Foot Ulcer Assessment and Management
- Endodontics and Root Canal Treatments
- Oral microbiology and periodontitis research
- Circular RNAs in diseases
- Surgical Sutures and Adhesives
- dental development and anomalies
- Pluripotent Stem Cells Research
- Extracellular vesicles in disease
- ZnO doping and properties
- Collagen: Extraction and Characterization
- CRISPR and Genetic Engineering
Royan Institute
2017-2025
Academic Center for Education, Culture and Research
2017-2025
University of Guilan
2016-2024
University of Rochester
2020
John Wiley & Sons (United States)
2020
Smith College
2020
Syracuse University
2020
The nanofibrous structure containing protein and polysaccharide has good potential in tissue engineering. present work aims to study the role of chitosan gelatin/chitosan scaffolds fabricated through electrospinning process under optimized condition. performance was evaluated by mechanical tests, scanning electron microscopy (SEM), Fourier transform infrared (FTIR) vitro cell culture on with different blend ratios. To assay influence ratio biocompatibility electrospun for skin engineering,...
Cells are very important to researchers due their use in various biological studies vitro and vivo settings. This importance stems from the short lifespan of most cells under laboratory conditions, which can pose significant challenges, such as difficulties associated with extraction source tissue, ethical concerns about separating human or animal models, limited cell passage ability, variation results differences obtained cells, among other issues. In general, conditions divide into a...
Abstract Crocin is a carotenoid compound in saffron with anti-cancer properties. However, its therapeutic application limited by low absorption, bioavailability, and stability, which can be overcome through nanocarrier delivery systems. This study used surface-modified Nano-crystalline cellulose (NCC) to deliver crocin cancer cells. NCC modified CTAB were loaded then conjugated folic acid (NCF-CR-NPs). The synthesized nanoparticles (NPs) characterized using FTIR, XRD, DLS, FESEM....
Abstract The study aims to assess the impact of graphene quantum dot-hyaluronic acid-quinoline nanocomposites (GQD-HA-Qu NCs) on MCF-7, HT-29, A2780, PANC-1, and HeLa cell lines. GQD-HA-Qu NCs were characterized using dynamic light scattering (DLS), field emission scanning electron microscopy (FESEM), Fourier-transform infrared (FTIR) spectroscopy. MTT assays flow cytometry evaluated cytotoxic apoptotic effects synthesized NCs. Additionally, real-time PCR was utilized gene expression. DLS...
Abstract Exosomes are required for the regenerative effects of human cardiosphere‐derived cells (CDCs). Studies show that they mimic cardioprotective benefits CDCs in rodents and porcine myocardial infarction (MI) models. Hypoxic preconditioning stem increases exosomes MI models by enhancing angiogenesis. Several exosomal microRNAs (miRNAs) up‐regulate response to hypoxia play a role pro‐angiogenic effects. In this study, we have demonstrated secreted under hypoxic conditions (1% O 2 days)...
Risk factors of nonhealing wounds include persistent bacterial infections and rapid onset dehydration; therefore, wound dressings should be used to accelerate the healing process by helping disinfect bed provide moisture. Herein, we introduce a transparent tributylammonium alginate surface-modified cationic polyurethane (CPU) dressing, which is appropriate for full-thickness wounds. We studied physicochemical properties dressing using Fourier transform infrared, 1H NMR, 13C NMR...
The efficacy of platelet-rich plasma (PRP) in enhancing muscle regeneration was limited due to uncontrolled delivery. This study focuses on modification decellularized scaffolds derived from skeletal extracellular matrix (ECM) by heparin, loading with PRP, enhance endogenous cell recruitment regeneration. Here, we showed an optimal decellularization procedure that effectively removed cells while preserving the ECM components tissue and macroporous suitable physical mechanical properties for...
In order to obtain a 3-dimentional scaffold with predictable clinical results for pulp regeneration, this study aims fabricate and characterize porous decellularized human amniotic membrane (HAM) extracellular matrix (ECM) scaffold, evaluate its potential promote regeneration in vitro vivo.The HAM was decellularized, histology DNA content were analysed confirm decellularization. The scaffolds synthesized 15, 22.5 30 mg/ml concentrations. porosity, pore size, phosphate-buffered saline (PBS)...
Myocardial infarction (MI) is a prevalent cause of mortality worldwide. In this study, sandwich scaffold was prepared for MI therapy using two commonly used materials in the medical field, polyglycerol sebacate (PGS) and polycaprolactone (PCL), series interrelated steps. The PGS/PCL nanofibers were coated with conductive polymer, i.e., polypyrrole (PPy), then embedded into decellularized myocardium gel to form 3D scaffold. Different quantitative qualitative evaluation tests performed, their...