- Eosinophilic Esophagitis
- Digestive system and related health
- Inflammatory Bowel Disease
- Inflammasome and immune disorders
- Gut microbiota and health
- Immune cells in cancer
- Gastroesophageal reflux and treatments
- Cancer-related molecular mechanisms research
- Bone Metabolism and Diseases
- Asthma and respiratory diseases
- Ginseng Biological Effects and Applications
- Lipid metabolism and disorders
- Extracellular vesicles in disease
- Magnesium in Health and Disease
- IL-33, ST2, and ILC Pathways
- Oral microbiology and periodontitis research
Chengdu University of Traditional Chinese Medicine
2024-2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Chongqing Medical University
2024
Periodontitis (PD) and type 2 diabetes mellitus (T2DM) represent interlinked global health burdens, commonly causing significant clinical complications when coincident. Therefore, managing both conditions (T2DM with periodontitis, DP) simultaneously poses considerable challenges, necessitating novel therapeutic strategies. KQJF has been clinically proven to treat DP good efficacy, but its pharmacological substances targets are not clear urgently need be clarified. To define the potential...
Abstract Background Inflammatory bowel disease (IBD) and allergic diseases possess similar genetic backgrounds pathogenesis. Observational studies have shown a correlation, but the exact direction of cause effect remains unclear. The aim this Mendelian randomization (MR) study is to assess bidirectional causality between inflammatory diseases. Method We comprehensively analyzed causal relationship (IBD), Crohn's (CD), ulcerative colitis (UC) (asthma, Hay fever, eczema) as whole,...
Introduction A variety of studies have shown a link between the gut microbiota and autoimmune diseases, but causal relationship with Henoch-Schönlein purpura (HSP) immune thrombocytopenic (ITP) is unknown. Methods This study investigated bidirectional causality HSP ITP using Mendelian randomization (MR). Large-scale genetic data at phylum to species level from MiBioGen consortium Dutch Microbiome Project were utilized. Genome-wide association (GWAS) summary statistics for came FinnGen R10....
Prior research has suggested a correlation between gallstones and depressive symptoms, yet the specifics of this relationship remain unclear. This study aims to explore association symptoms among adults.
ABSTRACT Objective This study aimed to investigate the effects of lipopolysaccharide (LPS)‐pretreated primary periodontal ligament stem cell (PDLSC)‐derived extracellular vesicles (EVs) (L‐PDLSC‐EVs) on periodontitis. Materials and Methods PDLSCs were obtained from mouse ligaments via enzymatic digestion. An in vitro inflammatory microenvironment for was established using LPS, L‐PDLSC‐EVs isolated through ultracentrifugation identified. EVs different treatments co‐incubated with RAW264.7...