Seokwon Lim

ORCID: 0000-0001-9974-2052
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About
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Research Areas
  • Proteins in Food Systems
  • Food composition and properties
  • Biosensors and Analytical Detection
  • Phytochemicals and Antioxidant Activities
  • Essential Oils and Antimicrobial Activity
  • Listeria monocytogenes in Food Safety
  • Pharmacological Effects of Natural Compounds
  • Natural product bioactivities and synthesis
  • Ginseng Biological Effects and Applications
  • Ziziphus Jujuba Studies and Applications
  • Freezing and Crystallization Processes
  • Lipid Membrane Structure and Behavior
  • Allergic Rhinitis and Sensitization
  • Advanced biosensing and bioanalysis techniques
  • Nanocomposite Films for Food Packaging
  • Advancements in Transdermal Drug Delivery
  • Surfactants and Colloidal Systems
  • Semiconductor materials and devices
  • Phytoestrogen effects and research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Microbial Metabolites in Food Biotechnology
  • Food Quality and Safety Studies
  • Meat and Animal Product Quality
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Bee Products Chemical Analysis

Gachon University
2021-2024

Chung-Ang University
2020-2023

Ajou University
2023

Hoseo University
2013-2020

University of Wisconsin–Madison
2009-2012

Seoul National University
2011-2012

University of California, Davis
1973-1974

To enhance the oral bioaccessibility of flavonoids, including quercetin, naringenin, and hesperetin, we prepared an edible oil-based lipid nanoparticle (LNP) system. Flavonoid-loaded LNPs were similar to blank LNP in physicochemical characteristics (z average <154.8 nm, polydispersity index <0.17, ζ potential < -40.8 mV), their entrapment efficiency was >81% at 0.3 wt % flavonoid concentration phase. In simulated digestion assay (mouth, stomach, small intestine), hydrolyzed under intestine...

10.1021/acs.jafc.5b01495 article EN Journal of Agricultural and Food Chemistry 2015-05-15

Propolis is a natural resinous substance made by bees through mixing various plant sources. has been widely recognized as functional food due to its diverse range of beneficial bioactivities. However, the therapeutic effects consuming propolis against atopic dermatitis (AD) remain largely unknown. The current study aimed investigate potential efficacy AD and explore active compound well direct molecular target. In HaCaT keratinocytes, inhibited TNF-α-induced interleukin (IL)-6 IL-8...

10.1002/biof.2119 article EN cc-by-nc BioFactors 2024-08-20

Visible indication based on the aggregation of colloidal nanoparticles (NPs) is highly advantageous for rapid on-site detection biological entities, which even untrained persons can perform without specialized instrumentation. However, since extent should exceed a certain minimum threshold to produce visible change, further applications this conventional method have been hampered by insufficient sensitivity or limiting characteristics target. Here we report signal amplification strategy...

10.1038/srep00456 article EN cc-by-nc-sa Scientific Reports 2012-06-13

The localized surface plasmon resonance (LSPR) effect of aggregating gold nanoparticles (AuNPs) has facilitated the development colorimetric biosensors that can potentially be employed on site. We have developed an effective strategy to enhance LSPR color-change signal by decoupling target detection and generation steps during immunobiosensing. biosensor consists streptavidin-coated AuNPs coupled with biotinylated antibacteria antibody as bifunctional linkers (BLs). While a BL function both...

10.1021/acsanm.9b02461 article EN ACS Applied Nano Materials 2020-01-15

10.3168/jds.s0022-0302(73)85264-6 article EN publisher-specific-oa Journal of Dairy Science 1973-07-01

Wheat germ (WG) is a by-product of wheat milling and comprises many bioactive compounds. This study aimed to compare the antioxidant antilipidemic effects different WG extracts (WGEs) by analyzing candidate compounds such as carotenoids, tocopherols, γ-oryzanol, biogenic amines reversed-phase high-performance liquid chromatography. Antioxidant activity was determined using ABTS, DPPH, FRAP assays. The effect evaluated in palmitic acid-induced steatosis HepG2 hepatocytes 3T3-L1 adipocytes....

10.3390/foods10051061 article EN cc-by Foods 2021-05-12

Abstract: Gold nanoparticles (AuNPs) were generated by mixing of gelatin solution and gold precursor (HAuCl 4, 1 mM) under isothermal condition (80 °C). The effects concentration (1% to 6%) pH (3, 5, 9) on the color signal gelatin‐templated AuNPs examined. λ max shifted from 535 552 nm at 1% gelatin, intensity was a maximum 2% gelatin. speed development accelerated 3, prepared 3 bigger (45 162 nm) more irregular in shape than those 5 or 9. When performance nanoreactor as time–temperature...

10.1111/j.1750-3841.2012.02872.x article EN Journal of Food Science 2012-08-17

Aggregation of unstable particles in water limits the application lipid nanoparticle (LNP) systems to foods despite capability encapsulate lipophilic bioactive components. This study exploits a preparation process that can reduce aggregation LNPs. Sonication during cooling step (postsonication) for 4, 5, or 6 min was applied increase covering effect Tween 20 on particle. Additionally, LNPs were prepared using fully hydrogenated canola oil (FHCO) blended with 0–30 wt % liquid (LCO) phase....

10.1021/jf503489v article EN Journal of Agricultural and Food Chemistry 2014-11-05

Abstract Acute or repetitive exposure to ultraviolet (UV) cause disruptions the skin barrier and subsequent inflammatory disease. 4‐phenylpyridine (4‐PP) is a constituent of Brassica campestris L. ssp. Pekinensis its effect on inflammation molecular target remain unclear. The purpose this study confirm anti‐inflammatory efficacy 4‐PP UVB‐induced in human keratinocytes HaCaT mouse validation target. also attenuated phosphorylation p38/mitogen‐activated protein kinase (MKK) 3/6, c‐Jun...

10.1111/jcmm.17422 article EN cc-by Journal of Cellular and Molecular Medicine 2022-06-10

10.3168/jds.s0022-0302(74)85062-9 article EN publisher-specific-oa Journal of Dairy Science 1974-11-01

Abstract On‐site detection for sensitive identification of foodborne pathogens on fresh produce with minimal use specialized instrumentation is crucial to the food industry. A switchable linker (SL)‐based immunoassay was designed ultrasensitive on‐site Salmonella in tomato samples. The assay based large‐scale aggregation gold nanoparticles (GNPs), induced by a quantitative relationship among biotinylated polyclonal antibody (b‐Ab) used as SL, functionalized GNPs, and . Important factors such...

10.1111/1750-3841.13861 article EN Journal of Food Science 2017-09-06
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