A5061749503- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- Erythrocyte Function and Pathophysiology
- Endoplasmic Reticulum Stress and Disease
- Whipple's Disease and Interleukins
- Gastrointestinal motility and disorders
- Food Allergy and Anaphylaxis Research
- Blood properties and coagulation
- Allergic Rhinitis and Sensitization
- Cellular transport and secretion
- Eosinophilic Esophagitis
- Platelet Disorders and Treatments
- Reproductive System and Pregnancy
- Dermatology and Skin Diseases
- Reproductive Physiology in Livestock
- Genetic and phenotypic traits in livestock
University of Rome Tor Vergata
2013-2020
Aston University
2015
Background: In gestational diabetes mellitus (GDM), pancreatic β-cell breakdown can result from a proinflammatory imbalance created by sustained level of cytokines. this study, we investigated the role specific cytokines, such as B-cell activating factor (BAFF), tumor necrosis α (TNF-α), and platelet-activating (PAF), together with methylglyoxal (MGO) glycated albumin (GA) in pregnant women affected GDM. Methods: We enrolled 30 whose inflammation metabolic markers were measured at...
Endoplasmic reticulum (ER) is the primary site for synthesis and folding of secreted membrane-bound proteins. Accumulation unfolded misfolded proteins in ER underlies a wide range human neurodegenerative disorders. Hence, molecules regulating stress response represent potential candidates as drug targets tackling these diseases. Protein disulphide isomerase (PDI) chaperone involved pathway, its activity being an important cellular defense against protein misfolding. Here, we demonstrate that...
Irritable Bowel Syndrome (IBS) is a widespread disease with variable symptoms that have an important impact on the quality of life. Despite prevalence IBS, its etiology and pathophysiology are still to be fully understood, but immune response known involved. In this study, we investigated variation two specific cytokines, B-cell activating factor (BAFF) platelet-activating (PAF), levels food-specific IgG symptom severity, using Syndrome-Symptom Severity Score (IBS-SSS), following...
Objective In pregnancies complicated by maternal obesity and diabetes, a disruption in inflammatory mediators occurs, resulting endothelial microvascular dysfunction, oxidative stress, tissue damage, feto-neonatal complications. To outline this proinflammatory status, an innovative approach is represented the measurement of cytokines. Among these biomarkers, B-cell-activating factor (BAFF) platelet-activating (PAF) play key role metabolic regulation, immune response to infections,...