A5005974028- Neuroscience and Neuropharmacology Research
- Social Policy and Reform Studies
- Labor market dynamics and wage inequality
- Social and Demographic Issues in Germany
- Social Policies and Healthcare Reform
- Employment and Welfare Studies
- Neural dynamics and brain function
- Gender, Labor, and Family Dynamics
- Retinal Development and Disorders
- Advanced Causal Inference Techniques
- Innovation, Technology, and Society
- Geological Studies and Exploration
- Neurogenesis and neuroplasticity mechanisms
- Sociology and Education Studies
- Mitochondrial Function and Pathology
- Geographic Information Systems Studies
- Barrier Structure and Function Studies
- Intermetallics and Advanced Alloy Properties
- German Economic Analysis & Policies
- Olfactory and Sensory Function Studies
- Ion channel regulation and function
- Photoreceptor and optogenetics research
- Muon and positron interactions and applications
- Neuropeptides and Animal Physiology
- Entrepreneurship Studies and Influences
Institut für Arbeitsmarkt und Berufsforschung
2013-2024
Friedrich Miescher Institute
2022-2023
University of Freiburg
2017-2022
Kohler (New Zealand)
2022
Employment Agency
2004-2021
Imerys (France)
2020
University of Göttingen
1994-2016
Dr. August Wolff (Germany)
2015
Centre National de la Recherche Scientifique
2011
Université de Strasbourg
2011
Abstract Motivation Generating publication ready plots to display multiple genomic tracks can pose a serious challenge. Making desirable and accurate figures requires considerable effort. This is usually done by hand or using vector graphic software. Results pyGenomeTracks (PGT) modular plotting tool that easily combines tracks. It enables reproducible standardized generation of highly customizable images. Availability implementation PGT available through graphical interface on...
The Galaxy HiCExplorer provides a web service at https://hicexplorer.usegalaxy.eu. It enables the integrative analysis of chromosome conformation by providing tools and computational resources to pre-process, analyse visualize Hi-C, Capture Hi-C (cHi-C) single-cell (scHi-C) data. Since last publication, has been expanded considerably with new facilitate cHi-C provide an in-depth Moreover, it supports scHi-C data offering broad range tools. With help standard graphical user interface Galaxy,...
Galaxy HiCExplorer is a web server that facilitates the study of 3D conformation chromatin by allowing Hi-C data processing, analysis and visualization. With server, users with little bioinformatic background can perform every step in one workflow: mapping raw sequence data, creation contact matrices, quality assessment, correction matrices identification topological associated domains (TADs) A/B compartments. Users create publication ready plots matrix, compartments, TADs on selected...
The primary problem with the explosion of biomedical datasets is not data, computational resources, and required storage space, but general lack trained skilled researchers to manipulate analyze these data. Eliminating this requires development comprehensive educational resources. Here we present a community-driven framework that enables modern, interactive teaching data analytics in life sciences facilitates training materials. key feature our system it static continuously improved...
Abstract The development of the 3 H‐GABA‐accumulating cells in neocortex has been followed by light microscopical autoradiography, and after resectioning original autoradiograms, electron microscopy. validity methods used are discussed. study limited to primary visual cortex its precursors rat, from embryonic day (E) 15 adult. GABA‐accumulating were found E 16 onwards occipital cortex, which is one two days arrive pallial anlage before first synapses have found. Until 18, prevalent positions...
The Freiburg RNA tools webserver is a well established online resource for RNA-focused research. It provides unified user interface and comprehensive result visualization efficient command line tools. includes RNA-RNA interaction prediction (IntaRNA, CopraRNA, metaMIR), sRNA homology search (GLASSgo), sequence-structure alignments (LocARNA, MARNA, CARNA, ExpaRNA), CRISPR repeat classification (CRISPRmap), sequence design (antaRNA, INFO-RNA, SECISDesign), structure aberration evaluation of...
In this study, we examined the long‐term effects of supporting welfare recipients by means a subsidy to start their own business. We used administrative data and propensity score matching estimate impact on probability receiving benefits unemployment status up 72 months after programme start. supplemented our estimation results with qualitative survey which provided insights into diversity entrepreneurial activities recipients' motivation for starting Our are encouraging. found stable...
Chromatin loops are an essential factor in the structural organization of genome; however, their detection Hi-C interaction matrices is a challenging and compute-intensive task. The approach presented here, integrated into HiCExplorer software, shows chromatin loop algorithm that applies strict candidate selection based on continuous negative binomial distributions performs Wilcoxon rank-sum test to detect enriched interactions.
Abstract A previously described serum‐free, defined medium (G2 medium) containing transferrin, selenium, hydrocortisone, biotin, fibroblast growth factor (FGF) and fibronectin developed for the of human rat derived glioma cells was investigated its ability to support proliferation astrocytes in primary cultures neonatal cerebrum. These were able grow G2 medium. Enhanced repeated subcultivation obtained after adding insulin and/or epidermal (EGF) at concentrations 5 μg/ml 10 ng/ml,...
Hohmeyer K, Wolff J. A fistful of euros: is the German one‐euro job workfare scheme effective for participants? Welfare reforms have constituted a major policy issue in many OECD countries recent decades. In Germany, reform 2005 emphasised activation welfare recipients and introduced programme –‘One‐Euro Jobs’– on large scale. present study, impact jobs employment prospects different groups participants was estimated. The analysis conducted sample using propensity score matching. other drawn...