This work reports a ZIF-8 (ZIF: Zeolitic Imidazolate Framework)-assisted NaYF4:Yb,Tm@ZnO upconverter for the photoelectrochemical (PEC) biosensing of carcinoembryonic antigen (CEA) under near-infrared (NIR) irradiation on homemade 3D-printed device with DNA walker-based amplification strategy. The composite photosensitive material NaYF4:Yb,Tm@ZnO, as converter to transfer NIR import photocurrent output, was driven from annealed NaYF4:Yb,Tm@ZIF-8. Yb3+ and Tm3+-codoped NaYF4 (NaYF4:Yb,Tm)...

A new double photosystems-based 'Z-scheme' photoelectrochemical (PEC) sensing platform is designed for ultrasensitive detection of prostate-specific antigen (PSA) by coupling with a three-dimensional (3D) DNA walker. Two photosystems consist CdS quantum dots (photosystem I; PS I) and BiVO4 photoactive materials II; II), whereas gold nanoparticles (AuNPs) photodeposited on high-active {010} facets are used as the electron mediators to promote transfer from conduction band II valence I. 3D...

This work has looked to explore an innovative and powerful visible fluorescence immunoassay method through wet NH3-triggered structural change of NH2-MIL-125(Ti) impregnated on paper for the detection carcinoembryonic antigen (CEA). Gold nanoparticles heavily functionalized with glutamate dehydrogenase (GDH) secondary antibody were used generation NH3 a sandwiched format. Paper-based analytical device (PAD) coated exhibited good intensity NH3-triggeried high accuracy reproducibility....

This work demonstrates that the photoelectric response of defect-engineered TiO2-x modified with Au nanoparticles can be modulated by oxygen vacancy concentration and excitation wavelength. When strongly plasmonic are anchored to DNA hybridization, several times enhancement photocurrent occurs under 585 nm excitation, it is employed as a novel signaling mode for developing an improved photoelectrochemical sensing platform. combined exonuclease III-assisted target recycling amplification...

With the introduction of gas-based contactless electrochemical biosensors lies prospects separating sensing interface from bioassembly platform, enhancing stability, and exploring signal transduction mechanism, all intimately linking to development immunoassay. Herein, we report on a H2-based biosensor whose signals derived chemical between H2 Pd nanowires@ZIF-67 (ZIF: Zeolitic Imidazolate Frameworks) bilayered for Dendritic Pt nanoparticles (DPNs) conjugated detection antibody were...

A class of 0-dimensional/2-dimensional (0D/2D) nanoheterostructures based on carbon quantum dots (CQDs) and graphitic nitride (g-C3N4) was designed as the signal-generation tags for sensitive photoelectrochemical (PEC) immunoassay prostate-specific antigen (PSA) coupling with copper nanoclusters (CuNCs). Combination CQDs g-C3N4 promoted photoexcited electron/hole separation largely increased photocurrents nanoheterostructures. Initially, a sandwich-type immunoreaction carried out monoclonal...

The organic-inorganic nanohybrids are emerging as one of the most attractive sensing materials in area gas sensors and usually exhibit some advanced properties because synergetic/complementary effects between organic molecules inorganic components. This work demonstrates a novel class nanohybrids, Cu2+-doped SnO2 nanograin/poly pyrrole nanospheres, for sensitive room-temperature H2S sensing. Doping Cu2+ nanograins remarkably enhances surface potential barrier by tailoring defects. After...

This work designs a simple low-cost visual fluorescence immunoassay for disease-related biomarkers (carcinoembryonic antigen, CEA, used as model protein) in biological fluids, based on the structural and optical transformation of CdTe quantum dots (QDs) immobilized paper induced by dissolved silver ions (Ag+) from nanoparticles (AgNPs) via cation-exchange reaction. A sandwich-type immunoreaction was initially carried out removable polystyrene high-binding microplate coated with monoclonal...

A ratiometric photoelectrochemical (PEC) sensing strategy was proposed for monitoring of carcinoembryonic antigen (CEA) based on a homemade 3D printing device with dual-working photoelectrodes (PE1 and PE2), coupling λ-exonuclease (λ-Exo)-assisted recycling amplification CdS quantum dots. Gold nanoparticles-functionalized ZnO nanorods were utilized as PEC substrate generating initial photocurrent immobilizing DNA probe. Upon incubation target trigger/CEA aptamer-modified magnetic bead...

Herein, a novel immunosensing strategy was designed for the sensitive fluorescence/visual detection of alpha-fetoprotein (AFP), by combining enzyme-controlled formation polydopamine (PDA) nanoparticles with dissolution manganese dioxide (MnO2) nanoflakes. Initially, sandwich-type immunoreaction fabricated on capture antibody-coated microplate using antibody/ascorbate oxidase-conjugating gold (AOX-AuNP-Ab2) as probe. The ascorbate oxidase, carried within immunocomplex, oxidized ascorbic acid...

A photothermal immune-imaging assay was innovatively designed for the visual quantitative detection of cancer biomarkers by coupling Cu_xS nanocrystals with a portable infrared thermal imager on smartphone.

A new enzyme-free and portable photoelectrochemical sensing method based on a homemade three-dimensional (3D) printing device was developed for accurate monitoring of low-abundance cancer biomarker (carcinoembryonic antigen, CEA, chosen as model analyte in this work), coupling glucose-encapsulated liposomes with digital multimeter readout.

(A) Schematic diagram of Co 9 S 8 nanoparticle-decorated CdS nanoflowers-based photoelectrochemical (PEC) aptasensor for the detection carcinoembryonic antigen (CEA); and (B) photocurrent response mechanism PEC bioanalysis.