A5075866378- Renin-Angiotensin System Studies
- Neonatal Respiratory Health Research
- Atrial Fibrillation Management and Outcomes
- Blood Pressure and Hypertension Studies
- Asthma and respiratory diseases
- Hormonal Regulation and Hypertension
- Apelin-related biomedical research
- Pediatric health and respiratory diseases
Grodno State Medical University
2024
BACKGROUND: Genetic and environmental factors are involved in the development of atrial fibrillation arterial hypertension. This determines relevance studying gene-environment interactions occurrence arrhythmia. AIM: To evaluate contribution renin-angiotensin-aldosterone system genes polymorphisms to susceptibility patients with hypertension, also study combined influence these on risk MATERIALS AND METHODS: The included 60 hypertension paroxysmal (study group), without (comparison group-1)...
The aim of the study is to establish association variants a number genes involved in reninangiotensin system with severity SARS-CoV-2 infection. included 206 hospitalized patients COVID-19: Group 1 – 99 severe COVID-19; 2 ‒ 107 moderate and mild forms disease. Polymorphic ACE rs4646994, ACE2 rs2074192 rs2285666 rs413031713 LZTFL1 rs10490770 were analyzed using quantitative PCR TaqMan probes (Primetech, Belarus) on CFX96 thermocycler (Bio-Rad, USA). AGT rs699 AGTR1 rs5186 gene determined...
Background. Cytokine and toll-like receptor gene polymorphisms may impact oral tolerance formation in infants. Objective: To determine the genotype distribution of IL-10 (G1082A, C592A) TLR 4 (Asp299Gly) children with different family history allergy residing Grodno region; to analyze association between concentrations fecal calprotectin (FCP) urine eosinophil protein X (UEoPX) Material Methods. 92 infants were recruited analyzed for polymorphisms. Concentrations FCP UEoPX examined dynamics...