A5089945252- Immunodeficiency and Autoimmune Disorders
- Blood disorders and treatments
- Childhood Cancer Survivors' Quality of Life
- Neutropenia and Cancer Infections
- Hematological disorders and diagnostics
- Acute Lymphoblastic Leukemia research
- Cancer Risks and Factors
- Pituitary Gland Disorders and Treatments
- Retinal Diseases and Treatments
- Ethics and Legal Issues in Pediatric Healthcare
- Immune Cell Function and Interaction
- Hematopoietic Stem Cell Transplantation
- Lymphoma Diagnosis and Treatment
- Retinal Imaging and Analysis
- Cancer Immunotherapy and Biomarkers
- Telemedicine and Telehealth Implementation
- Chronic Lymphocytic Leukemia Research
- Neuroscience of respiration and sleep
- Retinal and Optic Conditions
- Polyomavirus and related diseases
- Dermatological and COVID-19 studies
- Tuberous Sclerosis Complex Research
- Cystic Fibrosis Research Advances
- Disaster Response and Management
- Pediatric health and respiratory diseases
Gdańsk Medical University
2022-2024
Nicolaus Copernicus University
2016-2023
Collegium Medicum in Bydgoszcz
2016-2023
Antoni Jurasz University Hospital
2023
Bialystok University of Technology
2019
Polytechnic Institute of Viana do Castelo
2019
Medical University of Warsaw
2000-2017
Diabetic retinopathy (DR) is the leading cause of impaired vision in patients with diabetes mellitus. An adaptive optics retinal camera (rtx1™; Imagine Eyes, France) was used to capture images cones and arteries from DR. Cone parameters (density, interphotoreceptor distance, regularity) artery (wall thickness, lumen diameter, WLR, WCSA) were analyzed 36 nonproliferative DR (NPDR; 22 mild NPDR 14 moderate NPDR) 20 healthy volunteers (the control group). density at 2° eccentricities...
Inborn errors of immunity (IEI) refer to genetically determined disorders presenting with recurrent infections, autoimmunity, allergies, and malignancies. IEI is now commonly used, replacing the previously used term primary immunodeficiencies (PID). The 10 warning signs are widely in identification patients IEI. aim study was determine compare utility 14 diagnosing.A retrospective analysis 2851 performed (98.17% were subjects under 18 years old 1.83% adults). All questioned about four...
The appropriate skin hydration level enables its normal function and healthy appearance.The purpose of present research was to assess the applicability high frequency ultrasound (HFU) monitoring moisturization treatments.The study sample encompassed 27 women, aged 20-67 y.o. (mean age 45.48 y.o.) with dry skin. All women applied a strong moisturizing cream on their facial for 14 days. course treatment monitored using HFU. following parameters were subjected evaluation: epidermal echo...
Abstract Background Activated PI3K delta syndrome (APDS) belongs to the heterogeneous group of primary immunodeficiency disorders (PIDs). Progress in next-generation sequencing (NGS) enabled identification gain-of-function mutations phosphoinositide 3-kinase (PI3K) genes. Depending on type causative mutation, APDS is classified into two types: 1 and 2. To date, less than 100 cases have been reported. Clinical symptoms result from impaired immune regulation are clinically manifested by...
The anatomic structures of the anterior segment eye enable correct reception stimuli by retina, which contains receptors that receive light impulses and transmit them to visual cortex. aim this study was assess effect size sampling window in an adaptive optics (AO) flood-illumination retinal camera (rtx1) on cone density measurements eyes healthy individuals investigate differences spacing different quadrants retina. Thirty-three subjects with no ophthalmic or systemic disease underwent a...
Hydroa vacciniforme-like lymphoproliferative disorder (HV-LPD) is a cutaneous form of chronic active Epstein-Barrvirus (EBV) infection, which can develop into the extremely rare systemic lymphoma. Patients with Inborn errors immunity (IEI), such as common variable immunodeficiency (CVID), are at higher risk developing severe course infections especially viral and malignancies than general population. The aim study was to present complex diagnostic therapeutic management HV-LPD. clinical...
Common variable immunodeficiency (CVID) is one of the primary humoral immunodeficiencies. Despite inborn nature, first symptoms may appear in both children and adults. It characterized by hypogammaglobulinaemia, severe infections, autoimmunity, allergies, a predisposition to cancer. A delay diagnosis significant problem: time from disease implementation proper treatment usually very long. The consequence can be irreversible complications, which why it so important promote knowledge on this...
Introduction: We analyzed the epidemiology and outcomes of treatment invasive fungal disease (IFD) in children during anticancer therapy (PHO, pediatric hematology oncology) or after hematopoietic cell transplantation (HCT) over a period eight consecutive years single-center study. Material methods: Overall, total 254 HCTs were performed, 415 newly diagnosed for malignancy. Incidence, outcome IFD analyzed. Results: The cumulative incidence any was 32.6% allo-HCT, 22.2% PHO, 6.0% auto-HCT...
Accurate self-monitoring of blood glucose is the key to an effective and safe intensive insulin therapy. Indeed, most dosing decisions are made based on values obtained from home meters, in particular for those using diet planning carbohydrate counting. Patients that therapeutic regimen depend not only their ability accurately estimate content each meal but also accuracy meter being used. Therefore, order avoid postprandial hypoglycemia hyperglycemia, it great importance realize how...
Streszczenie Zakażenia są jednym z największych zagrożeń dla chorych w trakcie i po leczeniu chorób nowotworowych. Dla dzieci nieonkologicznymi schorzeniami hematologicznymi infekcje wiążą się ze zwiększonym ryzykiem powikłań, a także mogą być czynnikiem spustowym wystąpienia lub zaostrzenia problemu zdrowotnego. Jedynym skutecznym bezpiecznym sposobem zapobiegania zakażeniom szczepienia ochronne. Zalecenia odnośnie do ich realizacji zmieniają czasie, zależności od aktualnej sytuacji...
Abstract Introduction Leukemia belong to 31% of all childhood malignancies. Acute lymphoblastic leukemia (ALL) is the most frequent type pediatric accounting for 80–85% cases. Progress in diagnostics and therapy dependent on international cooperation. The objective study was analysis non-hematological toxicity during intensive chemotherapy according two consecutive intercontinental protocols. Patients methods A total number 210 children diagnosed ALL who were treated single center between...
Introduction: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Risk factors childhood ALL have changed during recent decades, mostly due to treatment personalization. The aim of this study was analyze therapy results and prognostic Kujawsko-Pomorski region Poland between 1976 2018. Material methods: Data from 495 patients (0–18 years old) diagnosed with 2018 analyzed. Prognostic were analyzed separately specific therapeutic groups, which defined by several...
Therapy results in pediatric Hodgkin lymphoma reflect remarkable progress oncology. In the last decade, relevant development of new therapeutic options for children with refractory or relapsed disease has been made. this study, we retrospectively analyzed therapy and risk factors treated a single oncology center according to five protocols. Data from 114 by institution between 1997 2022 were analyzed. Classic divided into four periods: 1997-2009, 2009-2014, 2014-2019, 2019-2022. For nodular...
Introduction: Over recent decades, significant progress in the treatment of childhood acute myeloid leukemia (AML) has been made. However, relapsed disease remains a challenge. The aim this study was to analyze therapy results pediatric patients treated for AML single oncology center, with particular focus on prognostic factors. Materials and methods: Data from younger than 19 years diagnosed between January 1994 December 2020 Department Pediatric Hematology Oncology Bydgoszcz, Poland...
Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children. The factors predisposing to ALL remain mostly unknown. Natural killer (NK) cells are a component of innate immunity. Their role eliminate that were infected with viruses or underwent neoplastic transformation. activity NK regulated by their activating and inhibitory receptors, inter alia killer-cell immunoglobulin-like receptors (KIRs). available data about link between incidence KIR genotype highly...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Grześk E, Dąbrowska A, Urbańczyk et al. Common variable immunodeficiency disorders – diseases with many faces. Pediatria Polska - Polish Journal of Paediatrics. 2018;93(2):186-191. doi:10.5114/polp.2018.76254. APA Grześk, E., Dąbrowska, A., Urbańczyk, Ewertowska, M., Tejza, B., & G. (2018). Paediatrics, 93(2), 186-191. https://doi.org/10.5114/polp.2018.76254 Chicago Elżbieta, Anna Marlena Barbara Grzegorz and...