A5008176198- Stress Responses and Cortisol
- HIV/AIDS Research and Interventions
- Tryptophan and brain disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Cancer survivorship and care
- Adolescent Sexual and Reproductive Health
- Bipolar Disorder and Treatment
- HIV Research and Treatment
- COVID-19 and Mental Health
- Sleep and related disorders
- Mindfulness and Compassion Interventions
- Health, psychology, and well-being
- Eating Disorders and Behaviors
- Blood Pressure and Hypertension Studies
- Medication Adherence and Compliance
- Cancer, Stress, Anesthesia, and Immune Response
- Psychosomatic Disorders and Their Treatments
- Behavioral Health and Interventions
- HIV-related health complications and treatments
- Cardiac Health and Mental Health
- Optimism, Hope, and Well-being
- HIV, Drug Use, Sexual Risk
- Family Caregiving in Mental Illness
- Migration, Health and Trauma
- Posttraumatic Stress Disorder Research
University of Connecticut
2014-2025
Miriam Hospital
1999-2021
Natchaug Hospital
2020
Hartford Financial Services (United States)
2020
UConn Health
2011-2012
University of Pennsylvania
2001-2005
Philadelphia University
2002
University of Miami
1995-2000
University of Iowa
2000
Providence College
1999
OBJECTIVE: Clinical and epidemiology studies have implicated depression as a risk factor in the morbidity mortality of many human diseases. This study sought to determine if was associated with alterations cellular immunity variables—specifically, natural killer (NK) cells CD8 T lymphocytes—in women HIV infection. METHOD: Ninety-three (63 HIV-seropositive, 30 HIV-seronegative) were studied part an ongoing longitudinal conducted at two sites. Subjects underwent extensive clinical,...
Objective This study examined the effects of a cognitive-behavioral stress management (CBSM) group intervention on serum cortisol levels in women being treated for stage I or II breast cancer. Methods Participants were randomly assigned to undergo 10-week ( N = 24) within 8 weeks after surgery placed waiting list (N 10). Cortisol was assessed by means radioimmunoassay blood samples collected at same time day just before start and immediately its completion. The also reported degree which...
The present study tested the effects of a multimodal cognitive-behavioral stress management (CBSM) intervention on anxious mood, perceived stress, 24-hr urinary catecholamine levels, and changes in T-lymphocyte subpopulations over time symptomatic HIV+ gay men. Seventy-three men were randomized to either group-based CBSM (n = 47) or wait-list control (WLC) condition 26). Men assigned showed significantly lower posttreatment levels self-reported anxiety, anger, total mood disturbance, less...
Abstract Background Warfarin is widely used to prevent stroke and venous thromboembolism despite its narrow therapeutic window. nonadherence a substantial problem, but risk factors have not been well elucidated. Methods A prospective cohort study of adults initiating warfarin at two anticoagulation clinics (University VA‐affiliated) was performed determine affecting warfarin. Nonadherence, defined by failure record correct pill bottle opening each day, measured daily via electronic...
Bereavement-specific written disclosure trials have generally demonstrated null effects, but these studies not directed the focus of writing. This randomized controlled trial compared writing that focused on either sense-making or benefit-finding, both associated with adjustment to loss, traditional, non-directed emotional and a control condition. Bereaved undergraduates (n = 68) completed three 20-min sessions over 1 week. Intervention effects were found prolonged grief disorder,...
Stress management interventions can reduce symptoms of distress as well modulate certain immune system components in persons infected with human immunodeficiency virus (HIV). These effects may occur parallel reductions hypothalamic-pituitary-adrenal (HPA) axis hormones such cortisol, which has been related other work to a down-regulation relevant HIV infection. The present study tested the multimodal cognitive-behavioral stress (CBSM) intervention on 24-hour urinary free cortisol levels and...
This study examined the effects of a 10-week cognitive-behavioral stress management (CBSM) intervention on dehydroepiandrosterone sulfate (DHEA-S) levels and ratio cortisol to DHEA-S (cortisol/DHEA-S), potential surrogate adrenal markers HIV disease progression, in relation alterations mood distress. HIV-seropositive men were randomized either group-based CBSM (n = 43) or wait-list control group 24), with both hormonal distress measures assessed just prior immediately following period....
Objective Coinfection with herpes simplex virus type 2 (HSV-2) is common in individuals infected human immunodeficiency (HIV) and may have health implications. This study examined the effect of a 10-week cognitive behavioral stress management (CBSM) intervention on immunoglobulin G (IgG) antibody titers to HSV-2 group mildly symptomatic HIV-infected gay men degree which these effects were mediated by psychosocial endocrine changes during period. Methods Sixty-two HIV+ randomly assigned...
OBJECTIVE: Changes in immunologic status were evaluated 25 HIV-infected men randomly assigned to a 10-week stress management intervention or wait-list control condition. METHOD: The authors monitored changes number of transitional naive T cells (CD4+CD45RA+CD29+) over 6–12 months after the completion intervention. RESULTS: Men receiving had higher CD4+ CD45RA+CD29+ cell counts at follow-up than did subjects. This difference was independent initial and HIV virus load. CONCLUSIONS: Stress is...
Limited health literacy is a known barrier to medication adherence among people living with HIV. Adherence improvement interventions are urgently needed for this vulnerable population.This study tested the efficacy of pictograph-guided skills-building counseling intervention limited adults HIV.Men and women HIV receiving antiretroviral therapy (N = 446) who scored <90% correct on test functional were partitioned into marginal lower groups randomly allocated 1 3 adherence-counseling...
Gay, bisexual, and other men who have sex with (MSM) remain the highest risk group for HIV infection. One reason is increased use of Internet to meet potential partners, which associated greater sexual behavior. To date, few studies investigated psychosocial predictors behavior among gay bisexual seeking partners online. The purpose current study was test a conceptual model relationships between trauma symptoms indexed on event diagnosis, internalized stigma, social support MSM seek A sample...
Objective: HIV stigma undermines health and well-being of people living with (PLWH). Conceptual work on mechanisms suggests that experiences or discrimination increase internalised stigma. However, not all PLWH may internalise the they experience. We aimed to investigate role stress associated events HIV-related stigma, as well downstream effects depressive symptoms alcohol use severity. Design: 199 participants were recruited from an clinic in southeastern United States. Main study...
OBJECTIVE: Depression is a potential risk factor for morbidity and mortality among patients with numerous medical conditions, including HIV disease, it also associated decrements in immune function, such as natural killer (NK) cell activity. This study examined whether improvements the diagnostic status of major depression are related to increases NK activity HIV-seropositive women. METHOD: women were recruited part longitudinal cohort underwent comprehensive psychiatric evaluations during...