Congcong Zeng

ORCID: 0000-0002-0066-2739
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About
Contact & Profiles
Research Areas
  • Sleep and related disorders
  • Sleep and Wakefulness Research
  • Medicinal Plants and Bioactive Compounds
  • Circadian rhythm and melatonin
  • Chronic Kidney Disease and Diabetes
  • Andrographolide Research and Applications
  • Pharmacological Effects of Natural Compounds
  • Epigenetics and DNA Methylation
  • Plant-based Medicinal Research
  • Phytochemistry and biological activity of medicinal plants
  • Obstructive Sleep Apnea Research
  • Biochemical Acid Research Studies
  • Kruppel-like factors research
  • 2D Materials and Applications
  • Cancer-related gene regulation
  • Connective Tissue Growth Factor Research
  • Ginkgo biloba and Cashew Applications
  • Renal cell carcinoma treatment
  • Genetic and Kidney Cyst Diseases
  • Perovskite Materials and Applications
  • MXene and MAX Phase Materials
  • Traditional Chinese Medicine Studies
  • Kidney Stones and Urolithiasis Treatments
  • Renal Diseases and Glomerulopathies
  • Systemic Sclerosis and Related Diseases

Wenzhou Medical University
2019-2024

First Affiliated Hospital of Wenzhou Medical University
2019-2024

Guilin Medical University
2022

Wenzhou Hospital of Traditional Chinese Medicine
2019-2020

Zhejiang Chinese Medical University
2014-2020

China Academy of Chinese Medical Sciences
2019-2020

Beijing University of Posts and Telecommunications
2020

Wenzhou City People's Hospital
2020

Xian Yang Central Hospital
2020

Wenzhou has achieved great progress in the prevention and control of growing coronavirus disease 2019 (COVID-19) pandemic, traditional Chinese medicine (TCM) played an indispensable role this fight. This study aimed to investigate efficacy Maxingshigan-Weijing decoction (MWD) treating infected patients.This was open-label randomized controlled trial. Inpatients with mild or moderate symptoms caused by severe acute respiratory syndrome 2 (SARS-CoV-2) infection were randomly treated routine...

10.1016/j.imr.2021.100782 article EN cc-by-nc-nd Integrative Medicine Research 2021-01-01

Jiao-Tai-Wan (JTW) is widely used for insomnia in traditional Chinese medicine. It has been found that berberine JTW a potential anti-insomnia effect, but the effect of volatile oil, which another major component JTW, remains unclear. To comprehensively analyze oil through chemical analysis, pharmacological research and network pharmacology methods. Gas chromatography-mass spectrometry (GC–MS) analysis platform were to elucidate material basis, mechanism treatment insomnia. A rat model...

10.1016/j.ccmp.2022.100023 article EN cc-by-nc-nd Clinical Complementary Medicine and Pharmacology 2022-02-26

Abstract Background Insomnia seriously affects people’s normal lives and work. However, effective treatment strategies are scarce. The purpose of this study is to explore the efficacy safety Jiao-tai-wan (JTW) for ameliorating insomnia symptoms caused by disharmony heart kidney. Design This a randomized, double-blind, placebo-controlled pilot clinical trial. A total 124 participants suffering from will be randomly assigned JTW or placebo group in an equal ratio. asked take granules twice day...

10.1186/s13063-020-04299-x article EN cc-by Trials 2020-05-15

[Formula: see text], a semiconductor with wide bandgap, has attracted attention due to its excellent workability in the short-wave region. Here, we reported mechanical, electronic and optical properties of bulk monolayer text] by using first-principles calculations. Our results show that both Young’s modulus Poisson’s ratio exhibit anisotropic behaviors. From structure, direct bandgap increases from 2.496 eV 3.030 eV. Compared exhibits small average effective mass significant anisotropy...

10.1142/s0217979220500344 article EN International Journal of Modern Physics B 2020-02-25

Abstract Background Insomnia seriously affects people’s normal lives and work. However, effective treatment strategies are scarce. The purpose of this study is to explore the efficacy safety Jiao-tai-wan (JTW) for ameliorating insomnia symptoms caused by disharmony heart kidney. Design This a randomized, double-blind, placebo-controlled pilot clinical trial. One hundred twenty-eight participants suffering from will randomly assigned JTW or placebo group in an equal ratio. be asked take...

10.21203/rs.2.510/v1 preprint EN cc-by Research Square (Research Square) 2019-03-28

Abstract Background: Renal fibrosis is the primary pathway in progression of chronic kidney disease (CKD) towards end-stage renal failure. The currently used drugs are ineffective, and their mechanisms action remain unclear. This study aims to investigate nephroprotective effect Improved-Nephropathy 1 Formula (N1F) a rat model unilateral ureteral obstruction (UUO) explore potential N1F-containing serum treating TGF-β1- induced human tubular epithelial cells (HK-2). Methods: chemical...

10.21203/rs.3.rs-3757443/v1 preprint EN cc-by Research Square (Research Square) 2023-12-18

Abstract Background: Insomnia seriously affects people’s normal lives and work. However, effective treatment strategies are scarce. The purpose of this study is to explore the efficacy safety Jiao-tai-wan (JTW) for ameliorating insomnia symptoms caused by disharmony heart kidney. Design: This a randomized, double-blind, placebo-controlled pilot clinical trial. One hundred twenty-eight participants suffering from will randomly assigned JTW or placebo group in an equal ratio. be asked take...

10.21203/rs.2.510/v2 preprint EN cc-by Research Square (Research Square) 2019-11-15

Abstract Introduction: The outbreak of a novel coronavirus (SARS-CoV-2) and associated COVID-19 disease in late December 2019 has led to global pandemic. It directly leads high morbidity mortality, but also results devastating effect on the economy. Unfortunately, there are no effective therapies or vaccines for it. Hence, we designed randomized trial evaluate efficacy safety Traditional Chinese Medicine treating patients with COVID-19. Methods analysis: This is an open-label, multicenter...

10.21203/rs.3.rs-25172/v1 preprint EN cc-by Research Square (Research Square) 2020-06-11

Abstract Background: Insomnia seriously affects people’s normal lives and work. However, effective treatment strategies are scarce. The purpose of this study is to explore the efficacy safety Jiao-tai-wan (JTW) for ameliorating insomnia symptoms caused by disharmony heart kidney. Design: This a randomized, double-blind, placebo-controlled pilot clinical trial. One hundred twenty- four participants suffering from will randomly assigned JTW or placebo group in an equal ratio. be asked take...

10.21203/rs.2.510/v4 preprint EN cc-by Research Square (Research Square) 2020-04-03

Abstract Background: Insomnia seriously affects people’s normal lives and work. However, effective treatment strategies are scarce. The purpose of this study is to explore the efficacy safety Jiao-tai-wan (JTW) for ameliorating insomnia symptoms caused by disharmony heart kidney. Design: This a randomized, double-blind, placebo-controlled pilot clinical trial. One hundred twenty-four participants suffering from will randomly assigned JTW or placebo group in an equal ratio. be asked take...

10.21203/rs.2.510/v3 preprint EN cc-by Research Square (Research Square) 2020-01-07
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