Changfeng Qu

ORCID: 0000-0002-0073-7577
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About
Contact & Profiles
Research Areas
  • Algal biology and biofuel production
  • Polar Research and Ecology
  • Seaweed-derived Bioactive Compounds
  • Biocrusts and Microbial Ecology
  • Microbial Community Ecology and Physiology
  • Genomics and Phylogenetic Studies
  • Marine and coastal plant biology
  • Photosynthetic Processes and Mechanisms
  • Light effects on plants
  • Echinoderm biology and ecology
  • Diet and metabolism studies
  • Marine and coastal ecosystems
  • Skin Protection and Aging
  • Fatty Acid Research and Health
  • Polysaccharides and Plant Cell Walls
  • Enzyme function and inhibition
  • Marine and environmental studies
  • Marine Invertebrate Physiology and Ecology
  • Gut microbiota and health
  • Helicobacter pylori-related gastroenterology studies
  • Infection Control and Ventilation
  • Ocean Acidification Effects and Responses
  • Marine Biology and Ecology Research
  • Diatoms and Algae Research
  • Protist diversity and phylogeny

Ministry of Natural Resources
2019-2025

First Institute of Oceanography
2017-2025

Qingdao National Laboratory for Marine Science and Technology
2018-2024

Ministry of Ecology and Environment
2023-2024

Guangxi Academy of Sciences
2022

University of Chinese Academy of Sciences
2015

Institute of Oceanology
2015

Tsinghua University
2012

An immunomodulatory polysaccharide (DAP4) was extracted, purified, and characterized from Durvillaea antarctica. The results of chemical spectroscopic analyses demonstrated that the a fucoidan, mainly composed (1→3)-α-l-Fucp (1→4)-α-l-Fucp residues with small degree branching at C-3 residues. Sulfate groups were C-4 (1→3)-α-l-Fucp, C-2 minor C-6 (1→4)-β-d-Galp. Small amounts xylose galactose exist in forms β-d-Xylp-(1→ β-d-Gal-(1→. activity DAP4 measured on RAW 264.7 cells, proved exhibited...

10.3390/md20040223 article EN cc-by Marine Drugs 2022-03-24

Background: Conjugated linoleic acid (CLA) is an effective supplement for reducing fat mass, but its effect on hepatic steatosis remains controversial. Objective: This study aims to evaluate the of CLA liver accumulation, inflammation, gut microbiome, and intestinal barrier integrity. Design: Wild-type (WT) mice ob/ob (OB) were randomly divided into four groups according treatment with/without 1% CLA: WT, WT treated with (WT-CLA), OB, OB (OB-CLA). Lipid metabolism accumulation evaluated by...

10.29219/fnr.v66.8226 article EN cc-by Food & Nutrition Research 2022-03-03

κ-Selenocarrageenan (KSC) is an organic selenium (Se) polysaccharide. There has been no report of enzyme that can degrade κ-selenocarrageenan to oligosaccharides (KSCOs). This study explored enzyme, κ-selenocarrageenase (SeCar), from deep-sea bacteria and produced heterologously in Escherichia coli, which degraded KSC KSCOs. Chemical spectroscopic analyses demonstrated purified KSCOs hydrolysates were composed mainly selenium-galactobiose. Organic foods through dietary supplementation could...

10.3390/ijms24054672 article EN International Journal of Molecular Sciences 2023-02-28

Laminaria japonica is a large marine brown alga that annually highly productive. However, due to its underutilization, potential value substantially wasted. For example, lot of cellulose remains unused during production algin. The soluble dietary fiber (SDF) was prepared from the byproducts japonica, and physicochemical properties were explored. SDF exhibits good water-holding, oil-holding, water-absorbing swelling, glucose cholesterol absorption capacity, inhibitory activity α-amylase...

10.3390/nu14020329 article EN Nutrients 2022-01-13

Although it is well recognized that mycosporine-like amino acids (MAAs) are ultraviolet (UV) protective agents can reduce UV damage, the specific biological mechanism of its role in skin remains unclear. In this study, we investigated effect MAAs extracted from Antarctic diatom Phaeodactylum tricornutum ICE-H on UVB-induced damage using a mice model. The components identified by liquid chromatography-tandem mass spectrometry included 4-deoxygadusol, shinorine, and porphyra-334, which were...

10.3390/ijms242015055 article EN International Journal of Molecular Sciences 2023-10-10

Psychrophilic green algae from independent phylogenetic lines thrive in the polar extreme environments, but hypothesis that their psychrophilic characteristics appeared through parallel routes of molecular evolution remains untested. The recent surge transcriptome data enables large-scale evolutionary analyses to investigate genetic basis for adaptations Antarctic environment, and identification selective forces drive is foundation understand strategies cold adaptation. Here, we conducted...

10.1093/gbe/evz104 article EN cc-by-nc Genome Biology and Evolution 2019-05-09

Though the relationship between dietary fiber and physical health has been investigated widely, use of from marine plants relatively rarely. The Saccharina japonica byproducts after production algin contain a large amount insoluble polysaccharide, which will cause waste resources if ignored. Soluble (SDF)prepared by alkaline hydrolysis method for first time had wrinkled microscopic surface low crystallinity, not only significantly reduced liver index, serum levels aspartate aminotransferase...

10.3390/md20020091 article EN cc-by Marine Drugs 2022-01-21

UVB radiation is known to trigger the block of DNA replication and transcription by forming cyclobutane pyrimidine dimer (CPD), which results in severe skin damage. CPD photolyase, a kind repair enzyme, can efficiently CPDs that are absent humans mice. Although exogenous photolyases have beneficial effects on diseases, mechanisms remain unknown. Here, this study prepared photolyase nanoliposomes (CPDNL) from Antarctic Chlamydomonas sp. ICE-L, thrives harsh, high-UVB conditions, evaluated...

10.3390/ijms232315148 article EN International Journal of Molecular Sciences 2022-12-02

Abstract The environment in Antarctica is characterized by low temperature, intense UVB and few vegetation types. Pohlia nutans M211 are bryophytes, which the primary plants can thrive well Antarctic harsh environment. transcriptional profiling of under temperature high conditions was analyzed to explore their polar adaptation mechanism extreme third-generation sequencing second-generation sequencing. In comparison earlier techniques, a total 43,101 non-redundant transcripts 10,532 lncRNA...

10.1186/s12870-023-04366-w article EN cc-by BMC Plant Biology 2023-08-22

The previous study successfully established an expression strain of ζ-carotene-like compounds (CLC) and demonstrated its remarkable antioxidant activity, which exhibited resistance to photodamage caused by UVB radiation on the skin following gavage administration. objective this was investigate impact mechanism CLC UVB-induced damage through topical application. Cell viability, anti-apoptotic ROS scavenging ability, inhibition melanin synthesis, regulation inflammatory factors collagen...

10.3390/ijms241813970 article EN International Journal of Molecular Sciences 2023-09-12
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