Abdus Saboor Shah

ORCID: 0000-0002-0089-9277
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About
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Research Areas
  • Nigella sativa pharmacological applications
  • Drug-Induced Hepatotoxicity and Protection
  • Liver Disease Diagnosis and Treatment
  • Epigenetics and DNA Methylation
  • Ubiquitin and proteasome pathways
  • Kruppel-like factors research
  • Genetic Syndromes and Imprinting
  • Wnt/β-catenin signaling in development and cancer
  • Essential Oils and Antimicrobial Activity
  • Complementary and Alternative Medicine Studies
  • Pancreatitis Pathology and Treatment
  • NF-κB Signaling Pathways
  • Phytochemistry and Biological Activities
  • Cancer-related Molecular Pathways
  • Pharmacological Effects of Natural Compounds
  • Liver physiology and pathology
  • Galectins and Cancer Biology
  • Phytochemicals and Antioxidant Activities
  • Peptidase Inhibition and Analysis
  • interferon and immune responses
  • Lipid metabolism and disorders
  • Ethnobotanical and Medicinal Plants Studies
  • Protease and Inhibitor Mechanisms
  • Cancer-related gene regulation

East China Normal University
2014-2019

University of Malakand
2018

University of Science and Technology
2014

University of Science and Technology Bannu
2013

Trifolium alexandrinum is traditionally used in various human ailments, including renal dysfunctions. The present experiment was designed to investigate antioxidant and nephroprotective effect of T. methanolic extract (TAME) against CCl4-induced oxidative stress albino rats. Results vitro study revealed significant (P < 0.05) effects. ameliorative role TAME also examined by investigating the level enzymes catalase (CAT), peroxidase (POD), glutathione (GSH-Px), glutathione-S-transferase...

10.1002/fsn3.152 article EN cc-by Food Science & Nutrition 2014-09-19

Abstract It has been reported that the proteasome activator REG γ is associated with multiple oncogenic pathways in human cancers. However, role of development melanoma and underlying mechanisms remain unclear. In this study, we attempted to investigate effects on cell proliferation vitro vivo. We demonstrated knockdown inhibited growth arrested at G1 phase. Furthermore, depletion also xenograft melanoma. Mechanistically, activates Wnt/β‐catenin signal pathway by degrading GSK ‐3β lines...

10.1111/exd.13394 article EN Experimental Dermatology 2017-06-12

Medicinal plants help in improving the human health that is primarily due to bioactive constituents such as flavonoids, alkaloids, saponins, cardiac glycosides and tannins. These compounds play important role minimizing oxidative stress, cancer, impotency, dysfunction microbial inhibition. Euphorbia prostrata (L) is a small prostrate, annual herb found all over the world including Pakistan. This study was designed investigate protective effects of E. prostrata against stress antibacterial...

10.5897/ajpp11.359 article EN African Journal of Pharmacy and Pharmacology 2011-08-31

Nicotiana plumbignifolia (Linn) is used as folk medicine in the treatment of liver dysfunction Pakistan. The present study was designed to investigate hepatoprotective role N. methanolice extract (NPME) against carbon tetrachloride (CCl 4 )-induced oxidative damage chicks. Methanolic obtained and further evaluated a agent CCl -induced For this study, 60-day-old 50 male chicks were divided into five groups. Chicks group 1 (control) had free access food water. Group II received mL/kg (30%...

10.1177/0748233713498448 article EN Toxicology and Industrial Health 2013-10-04
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