- Muscle activation and electromyography studies
- Cerebral Palsy and Movement Disorders
- Spinal Cord Injury Research
- Stroke Rehabilitation and Recovery
- Transcranial Magnetic Stimulation Studies
- Botulinum Toxin and Related Neurological Disorders
- Nerve Injury and Rehabilitation
- EEG and Brain-Computer Interfaces
- Musculoskeletal pain and rehabilitation
- Pain Management and Treatment
- Motor Control and Adaptation
- Shoulder Injury and Treatment
- Intraoperative Neuromonitoring and Anesthetic Effects
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurological disorders and treatments
- Spine and Intervertebral Disc Pathology
- Shoulder and Clavicle Injuries
- Vascular Malformations Diagnosis and Treatment
- Ergonomics and Musculoskeletal Disorders
- Cardiovascular Issues in Pregnancy
- Traumatic Brain Injury Research
- Prosthetics and Rehabilitation Robotics
- Balance, Gait, and Falls Prevention
- Cerebrospinal fluid and hydrocephalus
- Family and Disability Support Research
Baylor College of Medicine
1997-2012
United States Department of Education
2005-2012
United States Department of Health and Human Services
2009
Michael E. DeBakey VA Medical Center
2003-2005
Washington State University
2005
Baylor University
2002-2004
Dallas VA Medical Center
2002
Texas Woman's University
2001
Veterans Health Administration
1997-2001
Institute for Rehabilitation and Research Foundation
1980-2000
We investigated concerted evolution of rRNA genes in multiple populations Tragopogon mirus and T. miscellus, two allotetraploids that formed recurrently within the last 80 years following introduction three diploids (T. dubius, pratensis, porrifolius) from Europe to North America. Using earliest herbarium specimens (1949 1953) represent genomic condition near time polyploidization, we found parental rDNA repeats were inherited roughly equal numbers. In contrast, most present-day both...
Abstract In an attempt to demonstrate the presence of functional descending fibers in patients with clinically apparent spinal cord transection, we examined electromyographically recorded paralyzed leg muscle responses Jendrassik and other reinforcement maneuvers. Two patterns were observed: a low‐amplitude, short onset time maneuver response (RMR) restricted one three groups (RMR 1 ), larger‐amplitude longer that occurred bilaterally essentially all muscles 2 ). The imply preserved...
Intracranial compliance, as estimated from a computerized frequency analysis of the intracranial pressure (ICP) waveform, was continuously monitored during acute postinjury phase in 55 head-injured patients. In previous studies, high-frequency centroid (HFC), which defined power-weighted average within 4- to 15-Hz band ICP power density spectrum, found inversely correlate with pressure-volume index (PVI). An HFC 6.5 7.0 Hz normal, while an increase 9.0 coincided reduction PVI 13 ml and...
The averaged electrical potentials evoked by the stimulation of peripheral nerves were recorded with surface electrodes over lumbosacral, lower thoracic and cervical spine epidurally placed in area. waveforms lumbosacral spinal cord show similar complexity reflecting central generators. larger negative wave at least two components is followed a slower positive deflection. Evoked segments epidural are much higher amplitude more complex waveform than those electrodes.
The brain motor control assessment (BMCA) protocol is a comprehensive multichannel surface EMG recording used to characterize features in persons with upper neuron dysfunction. Key information contained the overall temporal pattern of unit activity, observed (RMS) envelope. In paralysis, rudimentary form suprasegmental tonic and phasic reflexes can be demonstrated. patterns evoked by voluntary passive maneuvers volitional modulation reflex responses reveal not apparent clinical examination....
Objective. This study was designed to characterize the rudimentary residual lower-limb motor control that can exist in clinically paralyzed spinal-cord-injured individuals. Methods. Sixty-seven subjects were studied using surface electromyography recorded from muscles of lower limbs and analyzed for responses a rigidly administered protocol reinforcement maneuvers, voluntary movement attempts, vibration, or ability volitionally suppress withdrawal evoked by plantar stimulation. Results....
Post-transplant lymphoproliferative disorder (PTLD) is a rare condition that occurs in patients who have undergone solid organ transplantation. Symptoms at presentation depend on the organs involved. PTLD most commonly first year after transplant (early onset) or around 5 years (late onset). Herein, we report of central nervous system an adult presented with seizures 17 renal After extensive infectious and transplant-related workup, brain biopsy confirmed diagnosis PTLD. The patient was...
The effectiveness of spinal cord stimulation for control spasticity was studied in 59 injury patients. SCS markedly or moderately effective reducing 63% the We found that by not correlated with severity spasticity, type (flexor extensor), ability to ambulate. However, more patients incomplete cervical lesions than complete lesions. Stimulation below lesion above. conclude when electrodes were properly positioned over posterior aspect some residual function. hypothesize controls modification...
Vertex transcranial magnetic stimulation (TMS) elicited tibialis anterior motor evoked potentials (MEPs) and silent periods (SPs) that were recorded during following isometric maximal volitional contraction (MVC). During MVC in 6 healthy subjects, MEP amplitudes the exercised muscle showed an increasing trend from initial value of 4539 ± 809 μV (mean SE) to 550 908 (P < 0.13) while force EMG decreased 0.01). Also, SP duration increased 165 37 ms 231 32 Thus, a fatiguing both excitatory...
We sought neurophysiologic evidence that spinal cord stimulation could modify the behavior of reflexes in 15 chronic SCI patients who showed beneficial effect SCS on spasticity. studied passive stretch, clonus, cutaneous touch, plantar reflex irradiation, and response to neck flexion reinforcement maneuver during by use surface PEMG recordings. Fifty-five percent responses were changed stimulation, but with widely varying patterns individual patients. Exceptional changes most or all...
Persons with spinal cord injury (SCI) may experience a range of symptoms typically labeled "spasticity." Previous efforts to develop assessment tools that measure spasticity have failed represent the experiences persons who live condition. The purpose this multicenter study was an instrument measures impact on quality life. Based 24 semistructured interviews, developmental form Patient Reported Impact Spasticity Measure (PRISM) constructed. PRISM administered 180 at five sites. Subscales...