A5024517576- Intracranial Aneurysms: Treatment and Complications
- Aortic aneurysm repair treatments
- Microbial metabolism and enzyme function
- Occupational and environmental lung diseases
- Pharmacogenetics and Drug Metabolism
- Neuroinflammation and Neurodegeneration Mechanisms
- Eicosanoids and Hypertension Pharmacology
- Inflammatory Bowel Disease
- Immunotoxicology and immune responses
- Biomarkers in Disease Mechanisms
- Carcinogens and Genotoxicity Assessment
- Drug Transport and Resistance Mechanisms
- Epigenetics and DNA Methylation
- Liver Disease Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Radiomics and Machine Learning in Medical Imaging
- Tuberculosis Research and Epidemiology
- Moyamoya disease diagnosis and treatment
- Glaucoma and retinal disorders
- Chemical Safety and Risk Management
- Pancreatic and Hepatic Oncology Research
- Therapeutic Uses of Natural Elements
- Lipid metabolism and disorders
- Traditional Chinese Medicine Studies
- Statistical Methods in Clinical Trials
Wenzhou Medical University
2012-2025
Ningbo Center for Disease Control and Prevention
2023
Central South University
2020-2022
Xiangya Hospital Central South University
2022
Beijing University of Chinese Medicine
2014-2022
Shenzhen Nanshan Center for Chronic Disease Control
2021
Weatherford College
2021
Bengbu Medical College
2016
Beijing Hospital
2012
Yunnan Center for Disease Control And Prevention
2012
This study aimed to investigate the potential influence of fish consumption on sleep disorders and their specific dimensions among adults in China. A cross-sectional was conducted involving 904 participants aged 28-95 from Wenling, Fish intake assessed using a Food Frequency Questionnaire containing 10 items. Sleep quality evaluated Insomnia Severity Index (ISI) Pittsburgh Quality (PSQI). Participants were categorized into three groups based weekly intake. Logistic regression analyses...
Aim: This study aims to systematically investigate the genetic polymorphisms of CYP2C19 gene and provide accurate data allele distribution pattern in Chinese Han population. Materials & Methods: We amplified all nine exons 2127 unrelated healthy subjects from two geographical locations (Zhejiang province, n = 1127; Hebei 1000), using direct sequencing. Results: In total, six previously reported alleles were found our study, which CYP2C19*6 CYP2C19*18 for first time subjects. addition, 35...
Intracranial aneurysm (IA) is a complex disease caused by genetic and environmental factors. Evidence indicates that inflammation plays an important role in IA occurrence. We aimed to explore the associations between inflammatory cytokine gene polymorphisms Chinese population. This study enrolled 768 participants of Han ethnicity, including 384 patients with healthy individuals. Sixteen single nucleotide (SNPs) IL1, IL6, IL12, TNF-α genes were genotyped using Sequenom MassARRAY platform....
Conventional approaches for patients with nonerosive gastroesophageal reflux disease (NERD) were not satisfactory. This study aimed to evaluate the effectiveness and mechanisms of Chinese herbal medicine Hewei Jiangni Decoction (HWJND) as a novel promising regimen NERD.A total 128 NERD randomly assigned Treatment group Control group. The from administered HWJND (81 g) plus dummy omeprazole (20 mg) daily 8 weeks, others given granules mg). clinical efficacy was assessed using questionnaire...
Purpose Intracranial aneurysms (IA) comprise a multifactorial disease with unclear physiological mechanisms. The lysyl oxidase ( LOX ) family genes , LOX–like 1–4 plays important roles in extracellular matrix (ECM) reconstruction and has been investigated terms of susceptibility to IA few populations. We aimed determine whether polymorphisms are associated Chinese population. Methods This case-control study included 384 patients healthy individuals without (controls). genotyped 27 single...
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease caused by intracranial aneurysm (IA) rupture. Lysyl oxidase (LOX) family genes (LOX-like [LOXL] 1-4) have roles in collagen cross-linking the extracellular matrix (ECM) and may be associated with IA We aimed to explore association between LOX polymorphisms risk of aSAH.This case-control study included 2 cohorts: 133 single ruptured 115 unruptured patients, 65 multiple 71 patients. Genotyping 27 nucleotide (SNPs) was...
Major accidents not only endanger the health and safety of population, but also bring bad influence to environment around. In order mitigate adverse effects, emergency response policy (ERP) corresponding protection action should be established. To maximize its effectiveness, ERP evaluated optimized, while most important criteria is minimizing consequence accident. A discrete state stochastic Markov process was used simulate movement evacuees in this paper. Solution provided expected...
目的 探讨慢性职业性苯中毒病因及早期诊断指标.方法从208例苯作业工人中选取20例外周血淋巴细胞微核和淋巴细胞百分比偏高者,分为高浓度(34～582mg/m3)接触组和低浓度(8～32 mg/m3)接触组,每组各10例;另设10例对照组,用流式细胞仪法检测各组骨髓单个核细胞早期凋亡指标Annexin V及调控凋亡的细胞因子白细胞介素(IL)-2、IL-4、IL-6和干扰素(IFN)-r的水平.结果(1)低浓度、高浓度苯接触工人淋巴细胞微核率分别为0.149%、0.308%,均高于对照组(0.060%),差异均有显著性(P＜0.05,P＜0.01).(2)低浓度组骨髓单个核细胞Annexin V阳性表达水平(0.70%±0.16%)与对照组(0.68%±0.22%)相比,差异无显著性(P＞0.05),而高浓度组骨髓单个核细胞Annexin...
Abstract Introduction: aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease caused by intracranial aneurysm (IA) rupture. Lysyl oxidase (LOX) family genes ( LOX-like [LOXL] 1–4 ) have roles in collagen cross-linking the extracellular matrix and may be associated with IA We aimed to explore association between LOX polymorphisms risk of aSAH. Methods This case-control study included two cohorts: 133 115 single ruptured unruptured patients, 65 71 multiple IAs respectively....