Asthma is a chronic respiratory disease characterized by variable airflow obstruction, bronchial hyperresponsiveness, and airway inflammation. Evidence suggests that air pollution has negative impact on asthma outcomes in the population. Extrinsic usually begins childhood, most patients have prior history of allergic diseases such as rhinitis, conjunctivitis, urticaria. This type closely related to hypersensitivity allergens house dust, pollen, molds, animal hair, organic chemical dust. Air...

Emerging zoonotic viral diseases pose significant public health challenges due to their high fatality rates, potential for widespread outbreaks, and profound socioeconomic impact. Human, animal, environmental interconnectedness highlights the need a collaborative One Health (OH) approach control prevent these diseases. With its diverse ecosystems rapid urbanization, India has witnessed several major outbreaks over past two decades, including Nipah virus, Kyasanur Forest Disease (KFD), H1N1...

The gut microbiota, consisting of trillions microorganisms residing in the gastrointestinal tract, has a profound influence on various aspects human health, including genetics and metabolism. Far from being passive passengers, these engage complex, bidirectional relationship with host, modulating gene expression metabolic processes. Emerging evidence reveals that microbiota can affect host genetic pathways, such as those involved immune responses inflammation. Moreover, plays pivotal role...

Every organism is constantly adapting to changes happening in the environment. This adaptation helps maintaining homeostasis. All organisms must adapt at molecular, cellular, physiological, and behavioral levels. Amongst many factors which act as a threat homeostasis, one of them stress. The has bring about both physiological changes. various researches recent years have shown that adverse life events, along with chronic stress, depression leads increased likelihood relapse patients...

Melanoma of the oral cavity is a rare malignant tumor that develops from melanocytic or de novo melanocytes within normal mucosa skin and appears blue, black, reddish-brown. Oral mucosal melanoma has higher proclivity for metastasis attacks tissue more aggressively than any other in mouth. Intestinal head neck an uncommon type cancer should be counted among deadliest. Malignant accounts only 0.2%-8.0% all reported melanoma, although accounting 1.3% malignancies. Because most melanotic...

The human gut microbiome, a complex community of microorganisms, profoundly influences health and disease. Bacteroidetes Firmicutes make up the majority normal microbiota. These microorganisms wield considerable influence over our physiological functions, impacting both well-being susceptibility to surge interest in microbiome past decade has been remarkable. Once overlooked, gastrointestinal tract's microbiota gained recognition for its significance maintaining optimal health. food industry...

Abstract Neuropharmacology explores how drugs influence the nervous system and their potential in treating neurological psychiatric disorders. This review provides a comprehensive overview of mechanisms through which various impact neural processes therapeutic applications. It covers major drug classes, including antipsychotics, antidepressants, anxiolytics neuroprotective agents, highlighting modes action, efficacy limitations. Advances development, such as targeted therapies novel...

Cavitary lung lesions have a specific array of differential diagnosis. Among rare causes is mucormycosis that should not be overlooked. A high index suspicion necessary for correct diagnosis and aggressive management. It usually occurs in immunosupressed patients. life-threatening, rapidly progressive, angioinvasive fungal infection. We present case pulmonary presenting as cavity an immunocompetent middle aged male.

In this case report, a 32-year-old female patient from Central India was reported. Her primary complaint pain and swelling in the lower left back region of her jaw, which had been present for one month. On extraoral examination, asymmetrical facial symmetry observed, 3 cm on side face. An intraoral examination showed reddish-pink ulceroproliferative growth buccal mucosa. Under local anesthesia, an incisional biopsy performed. A conclusive diagnosis well-differentiated squamous cell carcinoma...

Background: Diabetes mellitus leads in chronic metabolic syndromes worldwide. The physiochemicalchanges the blood bought about by persistent hyperglycemia are reflected hematological parameterson complete count.Introduction: Mellitus is a smouldering global pandemic destroying mankind slowly and silently.The associated detainable microvascular macrovascular complications responsible for much ofmorbidity mortality. With ever increasing incidence prevalence, it important to device...

The most prevalent brain condition that impairs function is migraine. A chronic migraine a very incapacitating disorder defined by having lasts for at least 10 days every month. Chronic patients commonly visit primary care, are advised to seek treatment in secondary and account large portion of the patient population specialized headache clinics. Using triptan, opioid, compound analgesic, or ergot derivative. significant, curable cause neurological impairment Making diagnosis essential, as...

Dear Editor, The advent of telemedicine has revolutionised the delivery global health care, especially during epidemic COVID-19. potential to address long-standing differences in rural care not yet been explored. In areas, medical access is often limited due geographical isolation, lack professionals and infrastructure challenges, so can be a transformational solution. these areas where services are scarce, there still significant obstacles maximising all its potential.[1] Telemedicine...

Abstract The animal flesh has been consumed for millions of years by humans. Although the attention increased in recent on its effect human genetics, exploring complex interplay between consumption and genetics sheds light both potential benefits risks associated with dietary choices.