A5025288054- Evolution and Genetic Dynamics
- Parasite Biology and Host Interactions
- Genetics, Aging, and Longevity in Model Organisms
- COVID-19 epidemiological studies
- Mathematical and Theoretical Epidemiology and Ecology Models
- Mosquito-borne diseases and control
- Aquatic Ecosystems and Phytoplankton Dynamics
- Genetic diversity and population structure
- Fish Ecology and Management Studies
- Genomics and Phylogenetic Studies
- COVID-19 Pandemic Impacts
- COVID-19 Impact on Reproduction
- Ecology and Vegetation Dynamics Studies
- Migration and Labor Dynamics
- Freshwater macroinvertebrate diversity and ecology
- Vibrio bacteria research studies
- Intergenerational Family Dynamics and Caregiving
- Zoonotic diseases and public health
- Bird parasitology and diseases
- Avian ecology and behavior
- Plant and animal studies
- Evolutionary Game Theory and Cooperation
- Species Distribution and Climate Change
- Viral Infections and Vectors
- Animal Ecology and Behavior Studies
University of Michigan
2015-2024
University of Minnesota, Duluth
2024
Pennsylvania State University
2020-2023
Center for Disease Dynamics, Economics & Policy
2021
Oberlin College
2011
Generalist parasites can strongly influence interactions between native and invasive species. Host competence be used to predict how an species will affect community disease dynamics; the addition of a highly competent, host is predicted increase disease. However, densities also impacts on dynamics. We examined whether information alone could accurately effects in hosts. first characterized relative parasite. Next, we manipulated composition mesocosms found that results did not While was...
Parasite fitness depends on a successful journey from one host to another. For parasites that are transmitted environmentally, abiotic conditions might modulate the success of this journey. Here we evaluate how light, key factor, influences spatiotemporal patterns zooplankton disease where light varies seasonally, across lakes, and with depth in lake. In an situ experiment using those three sources variation, tested sensitivity spores two ambient light. Infectivity both was lower when...
Abstract
A lack of tractable experimental systems in which to test hypotheses about the ecological and evolutionary drivers disease spillover emergence has limited our understanding these processes. Here we introduce a promising system: Caenorhabditis hosts Orsay virus, positive-sense single-stranded RNA virus that naturally infects C. elegans . We assayed species across tree found susceptibility 21 84 wild strains belonging 14 44 species. Confirming patterns documented other systems, detected...
Virulence, the degree to which a pathogen harms its host, is an important but poorly understood aspect of host-pathogen interactions. Virulence not static, instead depending on ecological context and potentially evolving rapidly. For instance, at start epidemic, when susceptible hosts are plentiful, pathogens may evolve increased virulence if this maximizes their intrinsic growth rate. However, host density declines during theory predicts evolution reduced virulence. Although well-studied...
Abstract Many organisms can reproduce both asexually and sexually. For cyclical parthenogens, periods of asexual reproduction are punctuated by bouts sexual reproduction, the shift from to has large impacts on fitness population dynamics. We studied populations Daphnia dentifera determine amount investment in as well factors associated with variation sex. To do so, we tracked host density, infections nine different parasites, 15 lake D. for 3 years. Sexual was seasonal, male ephippial female...
Abstract Myriad ecological and evolutionary factors can influence whether a particular parasite successfully transmits to new host during disease outbreak, with consequences for the structure diversity of populations. However, even though evolution populations are clear fundamental applied importance, we have surprisingly few studies that track how genetic parasites changes naturally occurring outbreaks in non‐human Here, used population approaches reveal genotypes bacterial parasite,...
Although individual parasite species commonly infect many populations across physical space as well multiple host species, the extent to which parasites traverse and phylogenetic distances is unclear. Population genetic analyses of can reveal how move or between including helping assess whether a more likely different in same location location. Identifying these transmission barriers could be exploited for effective disease control. Here, we analysed population structuring
The reproductive number R_0 (and its value after initial disease emergence R) has long been used to predict the likelihood of pathogen invasion, gauge potential severity an epidemic, and set policy around interventions. However, often ignored complexities have generated confusion use metric. This is particularly apparent with emergent pandemic virus SARS-CoV-2, causative agent COVID-19. We address some these misconceptions, namely, how R changes over time, varies space, relates epidemic size...
Many organisms can reproduce both asexually and sexually. For cyclical parthenogens, periods of asexual reproduction are punctuated by bouts sexual reproduction, the shift from to has large impacts on fitness population dynamics. We studied populations Daphnia dentifera determine amount investment in as well factors associated with variation sex. To do so, we tracked host density, infections nine different parasites, 15 lake D. for three years. Sexual was seasonal, male ephippial female...
ABSTRACT A lack of tractable experimental systems in which to test hypotheses about the ecological and evolutionary drivers disease spillover emergence has limited our understanding these processes. Here we introduce a promising system: Caenorhabditis hosts Orsay virus, positive-sense single-stranded RNA virus that naturally infects C. elegans . We assayed susceptibility species across tree found 21 84 wild strains belonging 14 44 be susceptible virus. Confirming patterns documented other...
Most parasite species infect multiple host species, and reciprocally, most hosts are infected by parasites. This leads to complex webs of interactions that influence disease within the community, making it challenging understand predict spread community epidemics. Here, we used network approaches analyze a multi-year time series dataset includes eight zooplankton (in Daphnia Ceriodaphnia genera) seven microparasite examine patterns cross-species transmission. These analyses suggest varied in...
Myriad ecological and evolutionary factors can influence whether a particular parasite successfully transmits to new host during disease outbreak, with consequences for the structure diversity of populations. However, even though evolution populations is clear fundamental applied importance, we have surprisingly few studies that track how genetic parasites changes naturally occurring outbreaks in non-human Here, used population approaches reveal genotypes bacterial parasite, Pasteuria...
Many organisms can reproduce both asexually and sexually. For cyclical parthenogens, periods of asexual reproduction are punctuated by bouts sexual reproduction, the timing shift from to has large impacts on fitness population dynamics. We studied populations Daphnia dentifera determine amount investment in as well factors associated with variation sex. To do so, we tracked host density, parasite infections, temperature, light attenuation 15 lake D. for three years. monitored infections nine...