A5029175813- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV Research and Treatment
- Sex work and related issues
- Liver Disease Diagnosis and Treatment
- HIV/AIDS drug development and treatment
- HIV/AIDS Impact and Responses
- Viral-associated cancers and disorders
- HIV-related health complications and treatments
- COVID-19 Clinical Research Studies
- Peripheral Nerve Disorders
- Cytomegalovirus and herpesvirus research
- Botulinum Toxin and Related Neurological Disorders
- COVID-19 and healthcare impacts
- Biosimilars and Bioanalytical Methods
- Hepatitis Viruses Studies and Epidemiology
- HIV/AIDS oral health manifestations
- HIV, TB, and STIs Epidemiology
- Migration, Health and Trauma
- Pregnancy and Medication Impact
- Sexual function and dysfunction studies
- Syphilis Diagnosis and Treatment
Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine
2022-2025
Erasmus MC
2023-2024
University of Copenhagen
2022-2023
Rigshospitalet
2022-2023
Erasmus University Rotterdam
2022-2023
Hvidovre Hospital
2023
London International Development Centre
2022
University College London
2022
Luhansk State Medical University
2017
Lviv National Musical Academy named after Mykola Lysenko
2013
IntroductionThe SARS-CoV-2 pandemic has hit the European region disproportionately. Many HIV clinics share staff and logistics with infectious disease facilities, which are now on frontline in tackling COVID-19. Therefore, this study investigated impact of current situation care continuity antiretroviral treatment (ART) supplies CEE countries.MethodsThe Euroguidelines Central Eastern Europe (ECEE) Network Group was established February 2016 to review standards for region. The group consists...
Older People Living with HIV (OPWH) combine both aging and HIV-infection features, resulting in ageism, stigma, social isolation, low quality of life. This context brings up new challenges for healthcare professionals, who now must aid patients a significant comorbidity burden polypharmacy treatments. OPWH opinion on their health management is hardly ever considered as variable to study, though it would help understand needs dissimilar settings.We performed cross-sectional, comparative study...
Undiagnosed HIV infection is a prominent clinical issue throughout Europe that requires the continuous attention of all healthcare professionals and policymakers to prevent missed testing opportunities late diagnosis. This systematic review aimed evaluate interventions increase rates case detection in European hospitals. Out 4598 articles identified, 29 studies fulfilled selection criteria. Most were conducted single Western capital cities, only one study was from Eastern Europe. The main...
With no expected vaccine for HIV in the near future, we aimed to define current situation and challenges pre- post-exposure prophylaxis (PrEP PEP) Central Eastern Europe (CEE). The Euroguidelines CEE Network Group members were invited respond a 27-item survey including questions on PrEP (response rate 91.6%). was licensed 68.2%; 95 centers offered estimated number around 9000. It available daily (40.1%), on-demand (13.3%), or both forms (33.3%). access <1−80%. Three major barriers lack of...
Chronic hepatitis C (HCV) in women of childbearing age is a major public health concern with ∼15 million aged 15-49 years living HCV globally 2019. Evidence suggests pregnancy associated adverse and infant outcomes. This includes ∼6% risk infants acquiring vertically, this the leading cause children globally. However, few countries offer routine universal antenatal screening, direct-acting antivirals (DAAs) are not approved for pregnant or breastfeeding although small clinical trials...
Although antiretroviral treatments have improved survival of persons living with HIV, their long-term use may limit available drug options. We estimated the prevalence heavily treatment-experienced (HTE) status and potential clinical consequences becoming HTE.EuroSIDA, a European multicenter prospective cohort study.A composite definition for HTE was developed, based on estimates resistance prior exposure to specific regimens. Risks progressing outcomes were assessed by Poisson regression,...
BackgroundAdequate identification and testing of people at risk for HIV is fundamental the care continuum. A key strategy to improve timely indicator condition (IC) guided testing.AimTo evaluate uptake recommendations in IC-specific guidelines European countries.MethodsBetween 2019 2021, experts reviewed guideline databases identify all national 62 ICs. The proportion IC recommending was reported, stratified by subgroup (HIV IC, country, eastern/western Europe, achievement 90-90-90 goals...
The aim of the study was to assess regression liver stiffness after successful direct-acting antiviral (DAA) treatment in patients with hepatitis C virus (HCV) monoinfection and HCV/-HIV coinfection. In addition, we aimed identify factors associated regression.We studied treated interferon-free DAA regimens a sustained virological response at week 12 (SVR12 ) or 24 (SVR24 post-treatment. Liver assessed by transient elastography (TE) before initiation end (median weeks).Of 214 enrolled...
(1) Background: Viral hepatitis C (HCV) and viral B (HBV) are common co-infections in people living with HIV (PLWH). All PLWH should be vaccinated against HBV A (HAV) treated for HCV. We aimed to compare testing, prophylaxis treatment of Central Eastern Europe (CEE) 2019 2022. (2) Methods: Data was collected through two on-line surveys conducted 2022 among 18 countries the Euroguidelines CEE (ECEE) Network Group. (3) Results: In all standard care screen HCV both years; screening HAV routine...
The use of pre-exposure prophylaxis (PrEP) is a safe and effective prevention option to all people at substantial risk HIV acquisition, irrespective gender. However, in most European countries PrEP services focus on key populations, particular men who have sex with (MSM). This study aims explore availability implementation for women across the region.An online survey was sent members Women Against Viruses Europe (WAVE) from 50 September 2019. It consisted 19 questions, including both...
Objectives Pre‐exposure prophylaxis (Pr EP ) for HIV infection has been introduced in only a few European countries. We investigated the potential to provide PrEP Central and Eastern region, neighbouring Methods The Euroguidelines Europe ( ECEE Network Group was formed February 2016 review standards of care region. Information related Pr collected through on‐line surveys. Respondents were recruited by members based on their involvement care. Results Seventy‐six respondents from 23 countries...
Objectives Pre‐exposure prophylaxis (PrEP) for HIV infection is an important intervention control of the epidemic. The incidence increasing in countries Central and Eastern Europe (CEE). Therefore, we investigated change PrEP use CEE over time. Methods Euroguidelines (ECEE) Network Group was initiated February 2016 to compare standards care viral hepatitis infections CEE. Data on access were collected from 23 through online surveys May–June 2017 (76 respondents) November 2018–May 2019 (28...
The extent to which controlled and uncontrolled HIV interact with ageing, European region of care calendar year follow-up is largely unknown.EuroSIDA participants were followed after 1 January 2001 grouped according current progression risk; high risk (CD4 cell count ≤350/μl, viral load ≥10 000 copies/ml), low ≥500 cells/μl, <50 copies/ml) intermediate (other combinations). Poisson regression investigated interactions between risk, age, incidence AIDS or non-AIDS events.A total 16 839...
HIV-positive patients may present lungs with multiple infections, which hinder differential diagnoses and the choice of treatment in course COVID-19, especially countries limited access to high-standard healthcare. Here, we aim investigate association between radiological changes poor COVID-19 outcomes among from Central Eastern Europe. Between November 2020 May 2021, Euroguidelines Europe Network Group started collecting observational data on HIV co-infections. In total, 16 European...
Objective: To evaluate time trends in pregnancies and pregnancy outcomes among women with HIV Europe. Design: European multicentre prospective cohort study. Methods: EuroSIDA has collected annual cross-sectional audits of between 1996 2015. Pregnancy data were extracted described. Odds modelled, adjusting for potential confounders using logistic regression generalized estimating equations. Results: Of 5535 aged 16 to <50 years, 4217 (76.2%) had information available, 912 (21.6%) reported...
Introduction: The COVID-19 pandemic has been challenging time for medical care, especially in the field of infectious diseases (ID), but it also provided an opportunity to introduce new solutions HIV management. Here, we investigated changes service provision across Central and Eastern European (CEE) countries before after outbreak. Methods: Euroguidelines Europe Network Group consists experts ID from 24 within CEE region. Between 11 September 29 2021, group produced on-line survey,...
Dried blood spots (DBS) have potential to improve access screening for antibodies hepatitis C virus (HCV). However, although several studies on off-label use of DBS been performed, date no HCV antibody serology test is formally approved with DBS. This study evaluated the performance INNOTEST® Ab IV enzyme immunoassay in paired and plasma samples, determine whether may be added intended use.Adults history treatment were prospectively enrolled from two sites Ukraine. prepared fingerstick whole...
The two main objectives were to evaluate the COVID-19 point prevalence and test performance of WHO case definition diagnose clinically in people with HIV West Ukraine.
Armed conflicts exacerbate the spread of infectious diseases. We assessed impact 2022 armed conflict in Ukraine on common sexually, bloodborne, and respiratory-transmitted diseases internally displaced people (IDP) Ukraine. A cross-sectional study (#aware.id) was conducted Lviv, Ukraine, from 3 May 2023 to 24 June 2024, including IDP seeking care for HIV, hepatitis B C, COVID-19, tuberculosis, sexually transmitted infections. After medical screening evaluate disease risk, we used rapid...
Abstract Background Confirming the efficacy of dolutegravir/lamivudine in clinical practice solidifies recommendations on its use. Methods Prospective cohort study (DUALING) 24 human immunodeficiency virus (HIV) treatment centers Netherlands. HIV RNA–suppressed cases were triple-drug antiretroviral regimens without prior virological failure or resistance and started dolutegravir/lamivudine. Cases 1:2 matched to controls by use dolutegravir-based regimens, age, sex, transmission route, CD4+...
Of an estimated 170,000 individuals in Ukraine living with HIV, approximately 60% are injecting drug users (IDUs). Despite demonstrated need for increased access to both antiretroviral therapy (ART) and opioid substitution (OST) Ukraine, integrated, comprehensive care HIV-infected IDUs remains limited. For this study, semi-structured interviews 15 healthcare staff were conducted at the Lviv Regional AIDS Center. These explored perspectives of Center’s integrated ART OST program on patient...
Abstract The risk of vertical transmission hepatitis C virus (HCV) is ≈6%, and there growing evidence that maternal HCV adversely affects pregnancy infant outcomes. However, antenatal screening not routinely provided in most settings, direct acting antivirals (DAA) are approved for pregnant/ breastfeeding women. We conducted a cross-sectional survey pregnant/post-partum women Egypt, Pakistan Ukraine to assess the acceptability universal DAA treatment scenario DAAs being use pregnancy. Among...