A5091718753- HIV-related health complications and treatments
- Cardiovascular Health and Disease Prevention
- Antibiotic Resistance in Bacteria
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- MicroRNA in disease regulation
- Antibiotic Use and Resistance
- Bone and Joint Diseases
- Reproductive tract infections research
- Orthopedic Infections and Treatments
- Bone health and treatments
- Infectious Diseases and Tuberculosis
- Pneumonia and Respiratory Infections
- Nutritional Studies and Diet
- HIV Research and Treatment
- Heart Rate Variability and Autonomic Control
- Hidradenitis Suppurativa and Treatments
- Biomarkers in Disease Mechanisms
- Hepatitis C virus research
- Head and Neck Surgical Oncology
- Autoimmune and Inflammatory Disorders
- Hepatitis B Virus Studies
- Oral Health Pathology and Treatment
- HIV, Drug Use, Sexual Risk
- Bacterial Identification and Susceptibility Testing
AHEPA University Hospital
2017-2025
Aristotle University of Thessaloniki
2017-2025
Post-surgical central nervous system infections (PCNSIs) are a major cause of morbidity, poor functional outcomes and mortality in neurosurgical patients. These complicate operations the CNS or related to use devices drainage catheters. Gram-negative bacteria, with multiple resistance patterns, often isolated these difficult treat, due suboptimal antibiotic therapeutic levels cerebrospinal fluid (CSF). This is retrospective study PCNSIs between 2014 2024 single center tertiary hospital...
The incidence of multidrug-resistant (MDR) bloodstream infections (BSIs) is associated with high morbidity and mortality. Little evidence exists regarding the epidemiology BSIs use appropriate empirical antimicrobial therapy in endemic regions. Novel diagnostic tests (RDTs) may facilitate improve patient management. Data were assessed from patients MDR Gram-negative bacteremia at a university tertiary hospital over 12-month period. In total, 157 episodes BSI included study. overall mortality...
In this study, we aimed to assess the prevalence of syphilis among people with human immunodeficiency virus (HIV; PWH) engaging in high-risk sexual behavior, determine stage syphilis, and evaluate treatment efficacy. A retrospective single-center cohort study was conducted at AHEPA University General Hospital Thessaloniki, focusing on PWH high risk for sexually transmitted infections (STIs) attending outpatient care from January 2019 December 2022. Sociodemographic clinical data were...
The incidence of multidrug-resistant (MDR) bloodstream infections (BSI) is associated with high morbidity and mortality. Little evidence exists regarding the epidemiology BSIs use appropriate empirical antimicrobial therapy in endemic regions. Novel diagnostic tests (RDTs) may facilitate improve patient management. Data from patients MDR GNB bacteremia at a university tertiary hospital were assessed over 12-month period. 157 episodes BSI included study. Overall mortality rate was 50,3...
The incidence of infectious spondylodiscitis has been increasing over the last few years. This reflects expanding elderly and immunocompromised populations rising implementation invasive spinal procedures. Infection may be inoculated into disc space directly during Osteomyelitis caused by Acinetobacter species is rare mainly multidrug-resistant strains. We present case a 72-year-old Greek woman with postoperative baumannii strain that was successfully treated, after she declined surgical...
Rationale: The simultaneous occurrence of pyoderma gangrenosum (PG) and chronic granulomatous disease (CGD) is uncommon few cases have been reported worldwide. Patient concerns: PG a rare, chronic, ulcerative, neutrophilic skin unknown etiology that requires immunosuppressive treatment. CGD belongs to Primary Immune Deficiencies in which the main defect lies an inability phagocytic cells generate superoxide making patients susceptible serious, potentially life-threatening bacterial fungal...
Background: Aortic-to-brachial pulse pressure (PP) amplification is a novel biomarker that prognosticates the cardiovascular risk above and beyond central aortic brachial blood pressure. This phenomenon modulated by left ventricular contractility chronotrophy, large-artery stiffness reflecting properties of microcirculation. However, relative importance these parameters as hemodynamic determinant PP remains elusive.Methods: A total 88 consecutive drug-naïve hypertensives underwent...
People with HIV (PWH) have an elevated risk of cardiovascular disease compared to those without HIV. This study aimed investigate the relative serum expression microRNAs (miRNAs) associated arterial stiffness, a significant marker disease. A total 36 male PWH and people HIV, matched for age, body mass index, pack years, dyslipidemia, were included in study. Participants history hypertension, diabetes mellitus, disease, cancer, or intravenous drug use excluded. Markers including...
The pathophysiology of human immunodeficiency virus (HIV)-associated bone loss is complex and to date largely unknown. In this study, we investigated serum expression microRNAS (miRNAs) linked metabolism in HIV-associated loss. This was a case-control study. Thirty male individuals with HIV infection (HIV+) osteoporosis/osteopenia (HIV+/OP+) (cases) 30 age-matched HIV+ normal mass (HIV+/OP−) (controls) were included the analysis. matched for age without (HIV−), also as second controls....
Objective: Carotid-femoral PWV (cfPWV) is considered as the ‘gold-standard’ measurement of arterial stiffness. According to 2013 ESH/ESC Guidelines for management hypertension, cfPWV > 10m/s indicative asymptomatic organ damage. The aim this study determine possible correlation between and HIV infection by extension effect in Design method: We studied 69 male HIV-infected individuals over 50 years old (mean: 54.44 ± 3.5 years) without diabetes mellitus no known history cardiovascular...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Objective: Measurement of blood pressure and diagnosis hypertension in children adolescents can be challenging. This is due to several factors such as conditions by which measurement takes place, the white coat effect but also increased physical activity during day. study assessed correlation clinic measurements daytime ambulatory BP that were examined a tertiary hospital. Design method: We 43 consecutive children. At baseline we measured office according international guidelines. Within 15...
Objective: HIV infection is associated with increased cardiovascular risk. Also, premature atherosclerosis more frequent in HIV-infected individuals when compared age-matched noninfected general population. According to 2013 ESH/ESC Guidelines for the management of arterial hypertension, carotid-femoral pulse wave velocity (cfPWV) > 10m/s, carotid wall thickening (intima-media thickness, IMT 0.9 mm) and plaque are subclinical markers stiffness representing asymptomatic organ damage. The...
Objective: Studies in children have shown a progressive increase arterial stiffness by measuring pulse wave velocity (PWV) during childhood, indicating structural alteration to the wall starting already early life. These changes are accelerated several conditions, obesity is one of most prevalent ones. Clinic blood pressure (BP) this context has been widely investigated and fewer data exist with ambulatory measurement (ABPM) central BP. The aim present study was investigate interrelation...
Objective: The initiation of highly active antiretroviral therapy (HAART) in 1996 dramatically changed the outcome HIV infection from a fatal disease to manageable chronic illness. However, and/or HAART are associated with accelerated atherosclerosis and increased risk cardiovascular events. According 2018 ESH/ESC Guidelines for management arterial hypertension, stiffness estimated as carotid-femoral pulse wave velocity (cfPWV) >10m/s is indicative hypertension-mediated organ damage...