- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Protist diversity and phylogeny
- Probiotics and Fermented Foods
- Plant Pathogenic Bacteria Studies
- Escherichia coli research studies
- Bacteriophages and microbial interactions
- RNA and protein synthesis mechanisms
- Parasitic Infections and Diagnostics
- Adaptive optics and wavefront sensing
- Astronomy and Astrophysical Research
- Stellar, planetary, and galactic studies
- Methane Hydrates and Related Phenomena
St Petersburg University
1994-2022
University of Wuppertal
2022
Bioinformatics Institute
2020-2021
Shigella are pathogens originating within the Escherichia lineage but frequently classified as a separate genus. genomes contain numerous insertion sequences (ISs) that lead to pseudogenisation of affected genes and an increase non-homologous recombination. Here, we study 414 E. coli strains assess contribution genomic rearrangements evolution. We found experienced exceptionally high rates intragenomic had decreased rate homologous recombination compared pathogenic non-pathogenic . The...
Paramecium (Ciliophora) systematics is well studied, and about twenty morphological species have been described. The may include several genetic species. However, molecular phylogenetic analyses revealed that the diversity within could be even higher has raised a problem of cryptic whose statuses remain uncertain. In present study, we provide characterization two novel While lynni n. sp., although morphologically similar to P. multimicronucleatum, phylogenetically separated from all other...
Abstract A new microsporidian species, Globosporidium paramecii gen. nov., sp. from Paramecium primaurelia is described on the basis of morphology, fine structure, and SSU rRNA gene sequence. This first case microsporidiosis in reported so far. All observed stages life cycle are monokaryotic. The parasites develop cytoplasm, at least some part population endoplasmic reticulum its derivates. Meronts divide by binary fission. Sporogonial plasmodium divides rosette-like budding. Early...
High plasticity of bacterial genomes is provided by numerous mechanisms including horizontal gene transfer and recombination via flanking repeats. Genome rearrangements such as inversions, deletions, insertions duplications may independently occur in different strains, providing parallel adaptation or phenotypic diversity. Specifically, might be responsible for virulence, antibiotic resistance antigenic variation. However, identification events requires laborious manual inspection...
Abstract Shigella are pathogens originating within the Escherichia lineage but frequently classified as a separate genus. genomes contain numerous insertion sequences (ISs) that lead to pseudogenization of affected genes and an increase non-homologous recombination. Here, we study 414 E. coli strains assess contribution genomic rearrangements evolution. We found experienced exceptionally high rates intragenomic had decreased rate homologous recombination compared pathogenic non-pathogenic ....
Paramecium is a free-living ciliate that undergoes antigenic variation and still the functions of these variable surface antigen coats in this non-pathogenic remain elusive. Only few genes have been described, mainly two model species P. tetraurelia strain 51 primaurelia 156. Given lack suitable sequence data to allow for phylogenetics deeper comparisons, we screened genomes six different serotype isolated 548 candidates. Our approach identified subfamilies isogenes individual serotypes were...
Abstract Motivation High plasticity of bacterial genomes is provided by numerous mechanisms including horizontal gene transfer and recombination via flanking repeats. Genome rearrangements such as inversions, deletions, insertions, duplications may independently occur in different strains, providing parallel adaptation. Specifically, might be responsible for multi-virulence, antibiotic resistance, antigenic variation. However, identification events requires laborious manual inspection...