A5061815907- Innovative Microfluidic and Catalytic Techniques Innovation
- Plasmonic and Surface Plasmon Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Photonic and Optical Devices
- Electrowetting and Microfluidic Technologies
- Photonic Crystals and Applications
- Advanced Biosensing Techniques and Applications
- 3D Printing in Biomedical Research
- Photoacoustic and Ultrasonic Imaging
- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Viral Infections and Immunology Research
- Listeria monocytogenes in Food Safety
- Microfluidic and Capillary Electrophoresis Applications
- RNA Interference and Gene Delivery
- Analytical Chemistry and Sensors
- Quantum Dots Synthesis And Properties
- Cell Image Analysis Techniques
- Liquid Crystal Research Advancements
- Animal Virus Infections Studies
- Advanced Fiber Optic Sensors
- Nonlinear Optical Materials Studies
- Additive Manufacturing and 3D Printing Technologies
- Semiconductor Lasers and Optical Devices
- Monoclonal and Polyclonal Antibodies Research
Osaka Metropolitan University
2022-2024
Tokyo Metropolitan University
2023-2024
Osaka Prefecture University
2021-2022
Osaka City University
2022
Abstract The efficient detection of protein biomarkers is critical for public health. However, the sensitivity conventional antigen test kits relatively low early diagnosis, and laboratory immunoassays require complex pretreatment processes overnight. If target nanomaterials could be remotely guided to site, simpler faster methods would developed. Here, we reveal mechanism light-induced immunoassay that anti-spike-protein antibodies SARS-CoV-2 were coated on our developed...
The unique characteristics of biological structures depend on the behavior DNA sequences confined in a microscale cell under environmental fluctuations and dissipation. Here, we report prominent difference fluorescence from dye-modified single-stranded light-induced assembly DNA-functionalized heterogeneous probe particles microwell several microliters volume. Strong optical forces Mie scattering microparticles accelerated hybridization, photothermal effect localized surface plasmons gold...
Abstract Rapid evaluation of functions in densely assembled bacteria is a crucial issue the efficient study symbiotic mechanisms. If interaction between many living microbes can be controlled and accelerated via remote assembly, cultivation process requiring few days ommitted, thus leading to reduction time needed analyze bacterial functions. Here, we show rapid, damage-free, extremely dense light-induced assembly over submillimeter area with “bubble-mimetic substrate (BMS)”. In particular,...
Plasmonic substrates have been extensively investigated due to their potential applications in fluorescence microscopy, chemical sensing, and photochemical reactions. The optical properties of the substrate depend on spatial temporal features plasmon excited. Hence, ability directly visualize dynamics is crucial. In this study, we excitation a plasmonic nanobowl consisting periodic hexagonal array nanoscale bowl-like structures developed with self-assembly. Near-field transmission imaging...
The light-induced force and convection can be enhanced by the collective effect of electrons (superradiance red shift) in high-density metallic nanoparticles, leading to macroscopic assembly target molecules. We here demonstrate application for drug delivery system with enhancement cell membrane accumulation penetration biofunctional molecules including cell-penetrating peptides (CPPs) superradiance-mediated photothermal convection. For induction around targeted living cells culture medium,...
Abstract The efficient detection of harmful viruses and protein biomarkers is critical for public health. However, the sensitivity conventional antigen test kits relatively low early diagnosis, laboratory immunoassays require complex pretreatment processes overnight. If target nanomaterials could be remotely guided to site, simpler faster methods would developed. Here, we reveal that nanoparticles modified with spike proteins SARS-CoV-2 can selectively detected 1/100 virus concentration in...
<title>Abstract</title> Detecting trace amounts of harmful bacteria and nanoscale biomarkers is essential for early diagnosis preventing food poisoning various diseases. Hindered by limited sensitivity speed due to dilute samples, conventional detection methods, such as cultivation techniques immunoassays, are expensive time-consuming. In contrast, optical condensation using photothermal convection bubbles facilitates rapid transport dense assembly dispersoids toward the observation area;...
Microbial interactions are closely related to human health, and secreted signal molecules from bacteria determine the gene expression of following bacterial cell density molecule density. However, conventional quantitative analysis number requires several days using standard cultivation methods, detection via microbial is difficult since they in extremely small amounts. In this study, we performed local fluorescence spectroscopy quantitatively evaluate assembly dispersoids (fluorescent...
We developed photothermal fiber-based module coated with metallic nanofilm to demonstrate optical condensation at Three-dimensionally arbitrary positions. By using this module, the assembly efficiency was improved about twenty times in comparison conventional method.
Optical condensation is a method for the rapidly and densely assembling dispersoids on substrate. Recently, we developed metallic nanofilm-coated optical fiber (MNOF) module to perform three-dimensionally arbitrary position in dispersion liquid although convection profile was limited case of two-dimensional photothermal source. In this work, investigate effect interface using MNOF by changing from Remarkably, assembly efficiency with can be 1 2 orders magnitude higher than that conventional...
We developed a portable optical condensation system with multiple compact laser modules, and demonstrated highly efficient light-induced assembly. Remarkably, we succeeded in assembly of bacteria beyond 10 5 cells within few minutes.
We developed photothermal fiber-based module coated with metallic nanofilm to demonstrate optical condensation at Three-dimensionally arbitrary positions. By using this module, the assembly efficiency was improved about twenty times in comparison conventional method.
We developed a plasmonic nano-bowl substrate exhibiting sensitive optical properties due to localized surface plasmons, and demonstrated the condensation detection of nanoparticles. Quantitative analysis nanoparticles was performed by fluorescence imaging reflectance spectroscopy.
We developed a plasmonic nano-bowl substrate exhibiting sensitive optical properties due to localized surface plasmons, and demonstrated the condensation detection of nanoparticles. Quantitative analysis nanoparticles was performed by fluorescence imaging reflectance spectroscopy.
We developed a portable optical condensation system with multiple compact laser modules, and demonstrated highly efficient light-induced assembly. Remarkably, we succeeded in assembly of bacteria beyond 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sup> cells within few minutes.