A5100681612- Photonic and Optical Devices
- Advancements in Battery Materials
- Semiconductor Lasers and Optical Devices
- Optical Network Technologies
- Organic Electronics and Photovoltaics
- Advanced Battery Materials and Technologies
- Advanced Photonic Communication Systems
- Organic Light-Emitting Diodes Research
- Manufacturing Process and Optimization
- Engineering Applied Research
- Advanced Battery Technologies Research
- Electrical and Thermal Properties of Materials
- Plant Virus Research Studies
- Conducting polymers and applications
- Ergonomics and Musculoskeletal Disorders
- Protein Structure and Dynamics
- Protein Degradation and Inhibitors
- Semiconductor materials and devices
- Extraction and Separation Processes
- Advanced Fiber Laser Technologies
- Technology and Data Analysis
- Advanced Cellulose Research Studies
- Perovskite Materials and Applications
- biodegradable polymer synthesis and properties
- Ubiquitin and proteasome pathways
University of Michigan–Ann Arbor
2021-2025
Samsung (South Korea)
2008-2024
Pusan National University
2016-2024
Merck & Co., Inc., Rahway, NJ, USA (United States)
2024
Electronics and Telecommunications Research Institute
2009-2023
University of California, San Diego
2010-2023
Korea Electric Power Corporation (South Korea)
2009-2023
Central Connecticut State University
2023
Scripps Research Institute
2012-2022
Quantitative BioSciences
2022
Abstract This study reviews the problems in use and disposal of poly (ethylene terephthalate) (PET) includes concise background virgin recycled PET as well their possible applications. The current state knowledge with respect to recycling method is presented. Recycling most desirable for waste management, providing an opportunity reductions oil usage, carbon dioxide emissions requiring because its non-degradability. Advanced technologies systems reducing contamination, mechanical chemical...
Finding narrow-band, ultrapure blue thermally activated delayed fluorescence (TADF) materials is extremely important for developing highly efficient organic light-emitting diodes (OLEDs). Here, spin-vibronic coupling (SVC)-assisted emitters obtained by joining two carbazole-derived moieties at a para position of phenyl unit and performing substitutions using several blocking groups are presented. Despite relatively large singlet-triplet gap (∆EST ) >0.2 eV, triplet-to-singlet crossover can...
Achieving narrow-bandwidth emission and high external quantum efficiency (EQE) simultaneously is a challenge for next-generation blue-emitting organic light-emitting diodes (OLEDs). In this study, novel multiple-resonance thermally activated delayed fluorescence (MR-TADF) emitters are developed by fusing an indolocarbazole unit with two carbazole skeletons using para-oriented nitrogen atoms. The resulting rigid planar π-system without electron-accepting atoms exhibits pure blue...
State-of-the-art methods in photoproximity labeling center on the targeted generation and capture of short-lived reactive intermediates to provide a snapshot local protein environments. Diazirines are current gold standard for high-resolution proximity labeling, generating aryl(trifluoromethyl) carbenes. Here, we present method access carbenes from stable diazo source via tissue-penetrable, deep red near-infrared light (600–800 nm). The operative mechanism this activation involves Dexter...
Aromatic residues are frequently found in helical and β-barrel integral membrane proteins enriched at the membrane−water interface. Although importance of these protein folding has been rationalized by thermodynamic partition measurements using peptide model systems, their contribution to stability bona fide never demonstrated. Here, we have investigated interfacial aromatic outer OmpA from Escherichia coli lipid bilayers performing extensive mutagenesis equilibrium experiments. Isolated...
Abstract Degradation of organic materials is responsible for the short operation lifetimes light-emitting devices, but mechanism by which such degradation initiated has yet to be fully established. Here we report a new emitting layers in blue-phosphorescent devices. We investigate binary mixtures wide bandgap host and series novel Ir(III) complex dopants having N -heterocyclocarbenic ligands. Our mechanistic study reveals charge-neutral generation polaron pairs (radical ion pairs) electron...
Abstract Much effort has been dedicated to increase the operational lifetime of blue phosphorescent materials in organic light‐emitting diodes (OLEDs), but reported device lifetimes are still too short for industrial applications. An attractive method increasing a given emitter without making any chemical change is exploiting kinetic isotope effect, where key CH bonds deuterated. A computer model identifies that most vulnerable molecular site an Ir‐phenylimidazole dopant benzylic bond and...
In this paper, we investigate the temperature dependence of a silicon-on-insulator-based silicon nanophotonic ring resonator covered with polymeric overlayer. Temperature-dependent wavelength shift is measured to be as low 5 pm/degC for TM mode in composed 500 times 220 nm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> channel waveguide. We also show through simulations and experiments that can reduced TE or both modes by adjusting volume
Significance CREB-binding protein (CBP) and its paralog p300 play a vital role in regulating gene transcription. Through the enzymatic activity of their histone acetyltransferase (HAT) domain, CBP control accessibility genes chromatin activate They also function as transcriptional repressors following SUMOylation cell cycle regulatory domain 1 (CRD1) located N-terminal to catalytic core. We present structural biochemical results showing that bromodomain, CH2, ZZ domains, which flank regulate...
Artificial intelligence based real-time microcirculation analysis system for laparoscopic colorectal surgery
Effective surface alkylation of cellulose nanocrystals (CNCs) was developed using a nucleophilic substitution reaction with an alkyl bromide to convert hydrophilic groups on the CNCs into and degree quantitatively determined. The resultant alkylated exhibited improved dispersion in nonpolar environment increased hydrophobicity, compared unmodified acetylated CNCs. Polylactide (PLA) nanocomposites reinforced modified were prepared by solution casting method effects reinforcement thermal...
Layered was prepared by ultrasonic spray pyrolysis. The discharge capacity increases linearly with of the upper cutoff voltage limit. attained a high over between 2.8 and 4.6 V an excellent cyclability. An in situ transition metal (TM) K-edge X-ray absorption spectroscopic (XAS) study carried out to investigate electronic local structures delithiated-relithiated system compared surface-sensitive soft XAS oxygen TM L-edges. bulk-sensitive analysis shows that charge compensation is made...
The mixed lineage leukemia (MLL) gene plays a critical role in epigenetic regulation of expression and is frequent target chromosomal translocations leading to leukemia. MLL plant homeodomain 3 (PHD3) lost all translocation products, reinsertion PHD3 into fusion proteins abrogates their transforming activity. has been shown interact with the RNA-recognition motif (RRM) domain human nuclear Cyclophilin33 (CYP33). Here, we show that CYP33 mediates downregulation genes HOXC8, HOXA9, CDKN1B,...
Interactions between proteins and carbohydrates are ubiquitous in biology. Therefore, understanding the factors that determine their affinity selectivity correspondingly important. Herein, we have determined relative strengths of intramolecular interactions a series monosaccharides an aromatic ring close to glycosylation site N-glycoprotein host. We employed enhanced sequon, structural motif found reverse turns some N-glycoproteins, facilitate face-to-face monosaccharide-aromatic...
To utilize thermally activated delayed fluorescence (TADF) technology for future displays, it is necessary to develop host materials which harness the full potential of blue TADF emitters. However, no publication has reported such hosts yet. Although most popular TADF, bis[2-(diphenylphosphino)phenyl]ether oxide (DPEPO) guarantees high-maximum external quantum efficiency (EQEmax ) devices, they exhibit very short operational lifetimes. In contrast, long-lifespan devices employing stable as...
Abstract Recent cryo-EM structures show the highly dynamic nature of MLL1-NCP (nucleosome core particle) interaction. Functional implication and regulation such dynamics remain unclear. Here we that DPY30 intrinsically disordered regions (IDRs) ASH2L work together in restricting rotational MLL1 complex on NCP. We binding to leads stabilization integration IDRs into establishes new ASH2L-NCP contacts. The significance ASH2L-DPY30 interactions is demonstrated by requirement both for dramatic...