A5002422775- Distributed and Parallel Computing Systems
- Advanced Data Storage Technologies
- Astronomy and Astrophysical Research
- Scientific Computing and Data Management
- Stellar, planetary, and galactic studies
- Parallel Computing and Optimization Techniques
- Neural dynamics and brain function
- Galaxies: Formation, Evolution, Phenomena
- Computer Graphics and Visualization Techniques
- Astronomical Observations and Instrumentation
- Advanced Fluorescence Microscopy Techniques
- Astrophysics and Star Formation Studies
- Neuroscience and Neural Engineering
- Digital Holography and Microscopy
- Interactive and Immersive Displays
- Geophysics and Sensor Technology
- Adaptive optics and wavefront sensing
- Advanced Optical Imaging Technologies
- Advanced Memory and Neural Computing
- Neuroscience and Neuropharmacology Research
- 3D Shape Modeling and Analysis
- Photoreceptor and optogenetics research
- Calibration and Measurement Techniques
- Near-Field Optical Microscopy
- Image Processing Techniques and Applications
Argonne National Laboratory
2011-2023
University of Chicago
2005-2023
University of Tennessee at Knoxville
2011
University of Memphis
2010
Office of Science
2010
California Institute of Technology
1981-1984
University of California, Berkeley
1977
Over the last 20 years, open-source community has provided more and software on which world’s high-performance computing systems depend for performance productivity. The invested millions of dollars years effort to build key components. However, although investments in these separate elements have been tremendously valuable, a great deal productivity also lost because lack planning, coordination, integration technologies necessary make them work together smoothly efficiently, both within...
Self-driving labs (SDLs) leverage combinations of artificial intelligence, automation, and advanced computing to accelerate scientific discovery.
The performance mismatch between computing and I/O components of current-generation HPC systems has made the critical bottleneck for scientific applications. It is therefore to make data movement as efficient possible, and, facilitate simulation-time analysis visualization reduce written storage. These will be paramount importance enabling us glean novel insights from simulations. We present our work in GLEAN, a flexible framework data-analysis acceleration at extreme scale. GLEAN leverages...
Constructing integrative visualizations that simultaneously cater to a variety of data types is challenging. Hybrid-reality environments blur the line between virtual and tiled display walls. They incorporate high-resolution, stereoscopic displays, which can be used juxtapose large, heterogeneous datasets while providing range naturalistic interaction schemes. thus empower designers construct more effectively mash up 2D, 3D, temporal, multivariate datasets.
This tutorial introduces the concepts and technologies needed to build projector-based display systems. Tiled displays offer scalability, high resolution, large formats for various applications. are an emerging technology constructing semi-immersive visualization environments capable of presenting high-resolution images from scientific simulation. The largest impact may well arise using large-format tiled as one possibly multiple in building information or active spaces that surround user...
There is growing concern that I/O systems will be hard pressed to satisfy the requirements of future leadership-class machines. Even current machines are found bound for some applications. In this paper, we identify existing performance bottlenecks in data movement on IBM Blue Gene/P (BG/P) supercomputer currently deployed at several leadership computing facilities. We improve by exploiting network topology BG/P collective I/O, leveraging semantics applications and incorporating asynchronous...
Brain electrical activity recorded during an epileptic seizure is frequently associated with rhythmic discharges in cortical networks. Current opinion clinical neurophysiology that strongly coupled networks and cellular bursting are prerequisites for the generation of epileptiform activity. Contrary to expectations, we found weakly can create synchronized seizure-like bursting. Evaluation a range synaptic parameters detailed computational model revealed occurs when excitatory synapses...
Most types of electrographic epileptiform activity can be characterized by isolated or repetitive bursts in brain electrical activity. This observation is our motivation to determine mechanisms that underlie bursting behavior neuronal networks. Here we show the persistent sodium (Na P ) current mouse neocortical slices associated with cellular and data suggest these cells are capable driving networks into a state. conclusion supported following observations. 1) Both low concentrations...
view Abstract Citations (98) References (50) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Near-Infrared Images of NGC 1068: Bar-driven Star Formation and the Circumnuclear Composition Thronson, Harley A., Jr. ; Hereld, Mark Majewski, Steven Greenhouse, Matthew Johnson, Paul Spillar, Earl Woodward, C. E. Harper, D. A. Rauscher, Bernard J. inner 1.5' (7.9 kpc) Seyfert galaxy 1068 at H (1.6 microns) K (2.2 both show an impressive stellar bar not found by...
This paper proposes the study of a new computation model that attempts to address underlying sources performance degradation (e.g. latency, overhead, and starvation) difficulties programmer productivity explicit locality management scheduling, tuning, fragmented memory, synchronous global barriers) dramatically enhance broad effectiveness parallel processing for high end computing. In this paper, we present progress our research on programming execution - mainly, ParalleX. We describe...
One of the most pressing issues with petascale analysis is transport simulation results data to a meaningful analysis. Traditional workflow prescribes storing disk and later retrieving them for visualization. However, at this storage full prohibitive. A solution problem run visualization concurrently bypass results. mechanism doing so in transit which on I/O nodes that receive but write information from or provide run-time This paper describes work progress three solutions, each using...
Current leadership-class machines suffer from a significant imbalance between their computational power and I/O bandwidth. forwarding is paradigm that attempts to bridge the increasing performance scalability gap compute components of meet requirements data-intensive applications by shipping calls nodes dedicated nodes. critical component subsystem IBM Blue Gene/P supercomputer currently deployed at several leadership computing facilities. In this paper, we evaluate existing mechanisms for...
Today's leadership computing facilities have enabled the execution of transformative simulations at unprecedented scales. However, analyzing huge amount output from these remains a challenge. Most analyses this is performed in post-processing mode end simulation. The time to read for analysis can be significantly high due poor I/O bandwidth, which increases end-to-end simulation-analysis time. Simulation-time reduce In work, we present scheduling in-situ as numerical optimization problem...
We have performed deep imaging of a diverse sample 26 low surface brightness galaxies (LSBGs) in the optical and near-infrared. Using stellar population synthesis models, we find that it is possible to place constraints on ratio young old stars (which parametrize terms average age galaxy), as well metallicity galaxy, using near-infrared colours. LSBGs wide range morphologies populations, ranging from older, high-metallicity earlier types much younger lower-metallicity late-type galaxies....
The authors present a graph‐based computational framework that facilitates the construction, instantiation, and analysis of large‐scale optimisation simulation applications coupled infrastructure networks. integrates modelling package PLASMO DMNetwork (built around PETSc ). These tools use common abstraction enables them to achieve compatibility between interfaces data structures modular creation exchange component models. also describe how embed these within complex workflows using SWIFT ,...
Advances in robotic automation, high-performance computing, and artificial intelligence encourage us to propose large, general-purpose science factories with the scale needed tackle large discovery problems support thousands of scientists.
Seizures in pediatric epilepsy are often associated with spreading, repetitive bursting activity neocortex. The authors examined onset and propagation of seizure-like using a computational model cortical circuitry. includes two pyramidal cell types four inhibitory interneurons. Each neuron is represented by multicompartmental biophysically realistic ion channels. determined the role neurons found that their capability driving network oscillations most prominent networks either weak or...
view Abstract Citations (64) References (44) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Subarcsecond Near-Infrared Imaging of Ultraluminous IRAS Galaxies Majewski, S. R. ; Hereld, M. Koo, D. C. Illingworth, G. Heckman, T. Near-infrared (NIR) K-band images with subarcsecond resolution are presented for the ultraluminous far-infrared (FIR) galaxies Mrk 273, Arp 220, and 15250+3609. Both 273 220 found to contain double nuclei arcsecond-scale separations...
Since Hartree–Fock theory often predicts stable negative ions to lie above the analogous neutral +e−, there have been legitimate concerns that structural predictions at this level of may be dubious value. To investigate question, ab initio electronic structure has applied methyl anion using large and flexible basis Duke. Electron correlation was taken into account explicitly recently developed self-consistent electron pairs (SCEP). The geometrical CH3− is found essentially unchanged by...
Accurate, precise, and rapid particle tracking in three dimensions remains a challenge; yet, its achievement will significantly enhance our understanding of living systems. We developed multifocal microscopy (MFM) that allows snapshot acquisition the imaging data, an associated image processing approach, together allow simultaneous 3D many fluorescent particles with nanoscale resolution. The was validated by measuring known trajectory bead axial accuracy 19 nm through depth (axial range) 3...
We report our finding that the South Pole is darkest known Earth-based site for near infrared astronomical observations. For this reason it has great potentail most sensitive surveys of distant or faint objects. find south polar sky background substantially darker in standard J, H, and K filters, an optimized KDARK filter centered at 2.36 microns. In particular, only 162 ± 67 mu-Jy arcsec-2 zenith. This consistent with results described accompanying paper by Ashley et al. 1996, comparable to...
Tiled displays systems built by combining the images from arrays of projectors can provide huge numbers pixel elements to applications needing visually represent lots information. Such are already coming into wide usage and include large scientific visualizations, collaborative virtual environments, rich multimedia spaces. It is, however, difficult create illusion a unified seamless display for variety reasons including optical distortion individual projector due imperfections in lenses...
Recent large-scale particle-based simulations are generating vast amounts of data posing a challenge to visualization algorithms. One possibility for addressing this is map particles into regular grid volume rendering, which carries the disadvantages inefficient use memory and undesired losses dynamic range. As an alternative, we propose method efficiently visualize these massive particle datasets using point rendering techniques with neither loss range nor overheads. In addition,...
Despite recent advances, high performance single-shot 3D microscopy remains an elusive task. By introducing designed diffractive optical elements (DOEs), one is capable of converting a microscope into "kaleidoscope," in which case the snapshot image consists array tiles and each tile focuses on different depths. However, acquired multifocal microscopic (MFM) suffers from multiple sources degradation, prevents MFM further applications. We propose unifying computational framework simplifies...