A5042164154- Marine Bivalve and Aquaculture Studies
- Invertebrate Immune Response Mechanisms
- Glycosylation and Glycoproteins Research
- Environmental Toxicology and Ecotoxicology
- Aquatic Invertebrate Ecology and Behavior
- Marine Biology and Environmental Chemistry
- Aquaculture disease management and microbiota
- Avian ecology and behavior
- Metabolism, Diabetes, and Cancer
- Antimicrobial Peptides and Activities
- Biological Research and Disease Studies
- Mitochondrial Function and Pathology
- Adipose Tissue and Metabolism
- Animal Ecology and Behavior Studies
- Species Distribution and Climate Change
- Botany and Plant Ecology Studies
- Ocean Acidification Effects and Responses
- Insect symbiosis and bacterial influences
- Marine Sponges and Natural Products
- Parasite Biology and Host Interactions
- Calcium Carbonate Crystallization and Inhibition
- Carbohydrate Chemistry and Synthesis
- Forest Insect Ecology and Management
- Ecology and biodiversity studies
- Parasites and Host Interactions
Far Eastern Federal University
2015-2024
A.V. Zhirmunsky National Scientific Center of Marine Biology Far Eastern Branch of the Russian Academy of Sciences
2021-2024
Bivalves play a key role in aquatic ecosystems and are valuable commercial resource. The prosperity of these organisms depends mainly on the effectiveness their immune defense, which hemolymph plays central role. Hemolymph may be used as an effective non-lethal criterion health. However, predictive value analysis comparison between obtained results reference data from healthy individuals living natural environments. We collected 15 commercially important species wild populations at stations...
Small peptides compose a large share of the mitochondrial proteome. Mitoregulin (Mtln) is peptide known to contribute respiratory complex I functioning and other processes in mitochondria. In our previous studies, we demonstrated that Mtln knockout mice develop obesity accumulate triglycerides oxidation substrates serum, concomitant with an exhaustion tricarboxylic acids cycle intermediates. Here examined functional role skeletal muscles, one major energy consuming tissues. We observed...
A small protein, Mitoregulin (Mtln), localizes in mitochondria and contributes to oxidative phosphorylation fatty acid metabolism. Mtln knockout mice develop obesity on a high-fat diet, demonstrating elevated cardiolipin damage suboptimal creatine kinase oligomerization muscle tissue. Kidneys heavily depend the mitochondria. Here we report kidney-related phenotypes aged mice. Similar mitochondria, those of kidney demonstrate decreased respiratory complex I activity excessive damage. Aged...
C1q domain-containing (C1qDC) proteins are a group of biopolymers involved in immune response as pattern recognition receptors (PRRs) lectin-like manner. A new protein MkC1qDC from the hemolymph plasma
Alterations of the cell-mediated and humoral immune parameters were revealed in bivalves Modiolus kurilensis from Sea Japan after injection with heat-inactivated Staphylococcus aureus. Preliminary screening vitro phagocytic activity (PA) hemagglutination (HA) enabled to obtain homogeneous groups individuals for all be measured. Changes hemolymph studied over a 14-day period. High values hemolytic (HL) protein concentration (PC) persisted until 36 h, high levels HA persisting 168 h. The PA...
Bivalves, such as Modiolus are used indicator organisms to monitor the state of marine environment. Even though hemocytes known play a key role in adaptive and protective mechanisms bivalves, these cells poorly studied horse-mussel kurilensis. In this paper, we present classification based on their immune functions, including production specific immune-related molecules, well morphological composition after isolation by density gradient centrifugation. An effective fractionation protocol was...
The rearing of saproxylic insects in laboratory conditions is an important task for studying the biology insects. Through understanding nutritional needs, it possible to optimize beetle conditions. In this study, artificial fungi-based diet (FD) was developed cultivation darkling Zophobas atratus (Fabricius, 1775) (Coleoptera: Tenebrionidae) as a model object saproxylophagous beetles. To assess influence diet, number physiological parameters were measured, including development time, body...
Over the past decade, Sivash Bay has undergone significant transformations due to blocking of North Crimean Canal. It resulted in a considerable increase salinity, which facilitated establishment feeding base for Greater Flamingo (Phoenicopterus roseus Pallas, 1811), characterized by substantial development brine shrimp (Artemia sp.) and chironomid larvae (Chironomidae). The warm winters recent years rest zone near Arabat Spit led formation nesting colony Flamingos. commenced mid-April 2024,...
Abstract The phenol oxidase system is ancient and ubiquitously distributed in all living organisms. In various groups it serves for the biosynthesis of pigments neurotransmitters (dopamine), defence reactions tissue hardening. Ascidians belong to subphylum Tunicata, which considered closest relative Vertebrates. Two oxidases previously described ascidians are vertebrate-like arthropod-like oxidases. our present study, we a new ascidian protein, Tuphoxin, with putative function, bears no...
A novel C1qDC bivalve protein from the Modiolus kurilensis (MkC1qDC-1) was identified, isolated and characterized. MkC1qDC-1 demonstrated inhibition of HeLa cell proliferation recognition some cancer phenotypes in comparative analysis on several lines, suggesting biomedical potential this protein.