SummaryBackgroundMultimorbidity, the presence of two or more mental physical chronic non-communicable diseases, is a major challenge for health system in China, which faces unprecedented ageing its population. Here we examined distribution multimorbidity relation to socioeconomic status; association between multimorbidity, health-care service use, and catastrophic expenditures; whether these associations varied by group social insurance schemes.MethodsIn this population-based, panel data...

The authors studies the correlation of methylphenidate medication in childhood with later drug abuse and growth height. Thirty adolescents histories minimal brain dysfunction who had been treated for at least six months chemotherapy were compared 30 not so treated. findings do indicate that prescribed contributed to or seriously interfered

Implications of multimorbidity patterns on health care utilisation and quality life in middleincome countries: cross-sectional analysis Background Past studies have demonstrated how single non-communicable diseases (NCDs) affect (QoL), but not different NCD combinations interact to these.Our study aims investigate the prevalence dyad triad combinations, implications QoL.Methods Our utilised data from WHO SAGE examine most prevalent six large middle-income countries (MICs).Subjects were...

Healthcare systems need to address the high healthcare use of frail older adults. The Geriatric Services Hub (GSH) is a novel program in Singapore that delivers frailty screening, comprehensive geriatric assessment and coordinated care for community-dwelling persons with bio-psycho-social needs. We aimed evaluate effects GSH on use.

Introduction: Many evidence-based healthcare innovations do not produce anticipated outcomes due to failure in accounting for contextual factors. We engaged potential implementers of a community-based integrated frailty and intrinsic capacity management older adults Singapore (the Innovation) elicit implementation barriers enablers. Theory/Methods: The updated Consolidated Framework Implementation Research (CFIR) its Outcomes Addendum (OA) was adopted as the conceptual framework assess...

Background The Ca2+-activated K+ channel KCa3.1 is expressed in several structural and inflammatory airway cell types proposed to play an important role the pathophysiology of asthma. aim current study was determine whether inhibition modifies experimental asthma sheep. Methodology Principal Findings Atopic sheep were administered either 30 mg/kg Senicapoc (ICA-17073), a selective inhibitor KCa3.1-channel, or vehicle alone (0.5% methylcellulose) twice daily (orally). Both groups received...

Multimorbidity, the presence of 2 or more non-communicable diseases (NCDs), is a major contributor to inequalities health in Australia and Japan. We use nationally representative data examine (i) relationships between multimorbidity with healthcare utilisation productivity loss (ii) whether these differed by socioeconomic groups.Cross-sectional analyses using Household, Income, Labour Dynamics (HILDA) Japanese Study Aging Retirement (JSTAR) surveys. examined 6,382 3,503 adults aged ≥50...

Abstract Background The burden of non-communicable diseases (NCDs) is rising rapidly in middle-income countries (MICs), where NCDs are often undiagnosed, untreated and uncontrolled. How comorbidity impacts diagnosis, treatment, control an emerging area research inquiry have important clinical implications as highlighted the recent National Institute for Health Care Excellence guidelines treating patients suffering from multiple NCDs. This first study to examine association between increasing...

This study aimed to examine the differences in multimorbidity between Aboriginal and Torres Strait Islander people non-Indigenous Australians, effect of on health service use work productivity.Cross-sectional sample Household, Income Labour Dynamics Australia wave 17.A nationally representative 16 749 respondents aged 18 years above.Multimorbidity prevalence pattern, self-reported health, employment productivity by Indigenous status.Aboriginal reported a higher (24.2%) compared with...

Abstract Background The first Patient-Centered Medical Home (PCMH) demonstration in Singapore was launched November 2016, which aimed to deliver integrated and patient-centered care for patients with bio-psycho-social needs. Implementation guided by principles of comprehensiveness, coordinated care, shared decision-making, accessible services, quality safety. We investigate the impact implementing PCMH primary on life (QoL) patient activation. Methods study design a prospective single-arm...

Physical non-communicable diseases (NCDs) and mental health disorders are a rapidly increasing burden in low-and middle-income countries. This study aims to examine the relationships between cascade of care managing four common physical NCDs (hypertension, diabetes, dyslipidemia, chronic kidney disease) China. We utilized two waves nationally-representative China Health Retirement Longitudinal Study (CHARLS 2011, 2015) older adult population aged 45 above. A series unadjusted adjusted...

Patient-Centred Medical Home (PCMH) is a strategy to enhance patient-centredness improve care experience. We aimed understand patient experience of an integrated PCMH model for complex community-dwelling older adults in Singapore. used mixed-method design with prospective single-group pre-post quantitative component and concurrent qualitative component. Participants were administered the validated Consumer Assessment Health Providers Systems Clinician & Group Survey (CG-CAHPS) at...

Background Chronic disease multimorbidity has become a major challenge for health systems. While lot of research evaluated the direct economic burden on care utilization and cost, little attention been given to impacts work productivity functional limitations, as indirect indicators burden.Objectives This study aims examine prevalence among Chinese adults its impact disability productivity. It also investigates urban-rural differences in these relationships.Method utilized data from China...

The global ageing population is associated with increased health service use. PCMH care model integrates primary and home-based management to deliver comprehensive personalised healthcare community-dwelling older adults bio-psycho-social needs. We examined if an integrated reduced utilisation burden of persons in Singapore. compared the between intervention group coarsened exact matched controls for a follow-up 15 months. Baseline matching covariates included socio-demographics, status, past...

Stroke is a major cause of mortality and long-term physical cognitive impairment. This study aims to: (1) examine the prevalence depressive symptoms, disability pain among Chinese adults with stroke; (2) test associations functional limitations body occurrence symptoms; (3) investigate gender urban-rural disparities in these associations. utilized data from China Health Retirement Longitudinal Study 2018, involving 969 patients stroke 17,970 participants aged ≥ 45 years. Depressive symptoms...

Background: There is a rapidly ageing population globally, leading to rise in subsidised public housing many countries for older adults. According the World Health Organisation, depression most prevalent mental disorder gap literature on factors associated with those residing studio apartments adults, characterised by small living spaces and isolated community settings. Objective: The aim of this study was examine associations between socio-demographic variables, social support,...

The Patient-Centred Medical Home (PCMH) demonstration in Singapore, launched November 2016, aimed to deliver integrated and patient-centred care for patients with biopsychosocial needs. Implementation was based on principles of comprehensiveness, coordinated shared decision-making.We conducted a prospective single-arm pre-post study design, which perform cost analysis PCMH from the perspectives patients, healthcare providers society. We assessed short-to-intermediate-term health-related...

Background: Multimorbidity, which is the presence of two or more chronic non-communicable diseases (NCDs), a growing challenge for health system in China, faces unprecedented ageing its population. This study examined: (1) distribution multimorbidity relation to economic status; (2) relationships between multimorbidity, healthcare service use, and catastrophic expenditures (CHE); (3), whether these varied by groups social insurance schemes China.Methods: We used data from three waves...

Abstract Background: Multimorbidity, the presence of ≥2 chronic conditions, is a major contributor to health inequalities, with significant impact on care costs. This study aims examine differences in physical and mental multimorbidity between Aboriginal Torres Strait Islander people non-Indigenous Australians, effect service use work productivity amongst Australians. Methods: conducted cross-sectional analyses Household, Income, Labour Dynamics Australia Wave 17, examining nationally...