- RNA regulation and disease
- Diet, Metabolism, and Disease
- Metabolism, Diabetes, and Cancer
- Pancreatic function and diabetes
- Prion Diseases and Protein Misfolding
- Viral gastroenteritis research and epidemiology
- RNA Research and Splicing
- Plant pathogens and resistance mechanisms
- SARS-CoV-2 and COVID-19 Research
- Identification and Quantification in Food
- Disaster Response and Management
- Muscle Physiology and Disorders
- Animal Virus Infections Studies
- Genetic Neurodegenerative Diseases
- Nuclear Receptors and Signaling
- Cancer Research and Treatments
- Plant-Microbe Interactions and Immunity
- Legionella and Acanthamoeba research
- Plant Pathogens and Fungal Diseases
- Essential Oils and Antimicrobial Activity
- Advanced Chemical Sensor Technologies
- Neurological diseases and metabolism
- Antifungal resistance and susceptibility
- Dental Research and COVID-19
Public Health Ontario
2022
Jiangnan University
2017-2021
Washington University in St. Louis
2007-2018
Nagasaki University
2000
University of Toronto
1990
Huntingtin N-terminal fragments (Htt-NTFs) with expanded polyglutamine tracts form a range of neurotoxic aggregates that are associated Huntington's disease. Here, we show aggregation Htt-NTFs, irrespective length, yields at least three phases (designated M, S, and F) delineated by sharp concentration thresholds distinct aggregate sizes morphologies. We found monomers oligomers make up the soluble M phase, ∼25-nm spheres dominate in S long, linear fibrils insoluble F phase. Previous studies...
Maca (Lepidium meyenii Walp.), originated in the high Andes of Peru, is rich nutrients and phytochemicals. As a new resource food China, suffers marketing disorders due to limitation basic research. Due close relationship quality origin place, it's scientific, economic social importance set up rapid, reliable efficient method identify origin. In present study, 303 samples were collected from 101 villages main producing area China. Using electronic nose BP neutral network algorithm, odor...
Abstract This work focused on the separation of active ingredients maca ( Lepidium meyenii Walpers) and evaluated antioxidative capability these components with effects improving glucose lipid metabolism in insulin‐resistant HepG2 cells. DPPH free radical scavenging reducing power assays were used to evaluate antioxidant activity extracts. An cell model induced by glucose, fructose, oleic acid, palmitic acid was adopted investigate extracts regulating this study. LC‐MS/MS then for...
On September 10, 2021, the Haliburton, Kawartha, Pine Ridge District Health Unit in Ontario, Canada, received a case report of Legionella pneumophila serogroup 1 patient (case 1) hospitalized for pneumonia. A second 2) within same household was also identified. Case laboratory diagnosed by urine antigen testing, whereas 2 PCR and culture from respiratory specimen collected 2, both at Public Ontario Laboratory, Canada. Cases were linked cases exposed via newly purchased but previously used...