A5015499091- Epigenetics and DNA Methylation
- Cancer-related gene regulation
- RNA modifications and cancer
- Acute Myeloid Leukemia Research
- Fire Detection and Safety Systems
- Tactile and Sensory Interactions
- Single-cell and spatial transcriptomics
- Advanced Sensor and Energy Harvesting Materials
- Immune cells in cancer
- Video Surveillance and Tracking Methods
- Muscle activation and electromyography studies
- Advanced Neural Network Applications
- Cancer Genomics and Diagnostics
Chinese Academy of Sciences
2021-2024
Beijing Institute of Genomics
2021-2024
Yantai University
2023
University of Chinese Academy of Sciences
2021-2023
Sino-Danish Centre for Education and Research
2021
Zhejiang University
2014
Forest fires are a vulnerable and devastating disaster that pose major threat to human property life. Smoke is easier detect than flames due the vastness of wildland scene obscuring vegetation. However, shape wind-blown smoke constantly changing, color varies greatly from one combustion chamber another. Therefore, widely used sensor-based fire detection systems have disadvantages untimely high false rate in middle an open environment. Deep learning-based object can recognize objects form...
This paper develops a novel flexible capacitive tactile sensor array for prosthetic hand gripping force measurement. The has 8 × (= 64) sensing units, each unit four-layered structure: two thick PET layers with embedded copper electrodes generates capacitor, PDMS film line-structure used as an insulation layer, and top bump layer to concentrate external force. structural design, working principle, fabrication process of this are presented. fabricated features high flexibility spatial...
Abstract The current challenge in analyzing sequencing-based spatial transcriptomics (ST) is to precisely resolve the distribution of cell subpopulations with low abundance and detect context-dependent variation states within complex tissue microenvironments. Here, we introduce an ultra-resolution ST deconvolution algorithm (UCASpatial) that improves resolution mapping locations by leveraging contribution genes indicative identity through entropy-based weighting. Using both silico real...
Azacitidine (AZA) is a DNA methyltransferase inhibitor and epigenetic modulator that can be an effective agent in combination with chemotherapy for patients high-risk acute myeloid leukemia (AML). However, biological factors driving the therapeutic response of such hypomethylating (HMA)-based therapies remain unknown. Herein, transcriptome and/or genome-wide 5-hydroxymethylcytosine (5hmC) characterized 41 AML from phase 1 clinical trial treated AZA priming followed by high-dose cytarabine...