- Advanced biosensing and bioanalysis techniques
- Molecular Sensors and Ion Detection
- Advanced Chemical Sensor Technologies
- Metal-Catalyzed Oxygenation Mechanisms
- Biosensors and Analytical Detection
- Luminescence and Fluorescent Materials
- Metal complexes synthesis and properties
- Analytical chemistry methods development
- Chemical Synthesis and Analysis
- Photosynthetic Processes and Mechanisms
- Antibiotics Pharmacokinetics and Efficacy
- Advanced Fluorescence Microscopy Techniques
- Lanthanide and Transition Metal Complexes
- Analytical Chemistry and Chromatography
- Analytical Chemistry and Sensors
- Radical Photochemical Reactions
- Photodynamic Therapy Research Studies
- Water Quality Monitoring and Analysis
- Biochemical Analysis and Sensing Techniques
- Nanoplatforms for cancer theranostics
University of Alabama
2020-2021
University of Jinan
2021
Tuscaloosa City Schools
2020
University of Leicester
2018
Ruthenium complexes bearing protic diimine ligands are cytotoxic to certain cancer cells upon irradiation with blue light. Previously reported of the type [(N,N)2Ru(6,6'-dhbp)]Cl2 6,6'-dhbp = 6,6'-dihydroxybipyridine and N,N 2,2'-bipyridine (bipy) (1A), 1,10-phenanthroline (phen) (2A), 2,3-dihydro-[1,4]dioxino[2,3-f][1,10]phenanthroline (dop) (3A) show EC50 values as low 4 μM (for 3A) vs breast light ( Inorg. Chem. 2017, 56, 7519). Herein, subscript A denotes acidic form complex OH groups, B...
A fluorescent macromolecular chemosensor, built from readily available components, performs chemical fingerprinting of carboxylate anions on low-cost, disposable paper supports.
Carboxylate anions are analytical targets with environmental and biological relevance, whose detection is often challenging in aqueous solutions. We describe a method for discrimination quantitation of carboxylates water buffered to pH 7.4 based on their differential interaction supramolecular fluorescent sensor, self-assembled from readily available building blocks. A fifth-generation poly(amidoamine) dendrimer (PAMAM G5), bound organic fluorophores (calcein or pyranine) through noncovalent...
We report new ruthenium complexes bearing the lipophilic bathophenanthroline (BPhen) ligand and dihydroxybipyridine (dhbp) ligands which differ in placement of OH groups ([(BPhen)
Penicillins and cephalosporins belong to the β-lactam antibiotic family, which accounts for more than half of world market antibiotics. Misuse antibiotics harms human health environment. Here, we describe an easy, fast, sensitive optical method sensing discrimination two penicillin five cephalosporin in buffered water at pH 7.4, using fifth-generation poly (amidoamine) (PAMAM) dendrimers calcein, a commercially available macromolecular polyelectrolyte fluorescent dye, respectively. In...
Fluorogens with aggregation-induced emission (AIE) characteristics have recently been widely applied for studying biological events, and fluorogens “smart” properties are especially desirable. Herein, we rationally designed synthesized a biotinylated reduction-activatable probe (Cys(StBu)-Lys(biotin)-Lys(TPE)-CBT (1)) AIE cancer-targeted imaging. The 1 can be actively uptaken by the biotin receptor-overexpressing cancer cells, then “smartly” self-assemble into nanoparticles inside cells turn...