A5000874899- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- Healthcare Systems and Practices
- HIV-related health complications and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Hepatitis C virus research
- Health, Medicine and Society
- Hepatitis B Virus Studies
- Cervical Cancer and HPV Research
- Plant Disease Resistance and Genetics
- Advanced Radiotherapy Techniques
- SARS-CoV-2 and COVID-19 Research
- Prostate Cancer Treatment and Research
- COVID-19 epidemiological studies
- Neonatal Health and Biochemistry
- Polyomavirus and related diseases
- Acute Kidney Injury Research
- Prostate Cancer Diagnosis and Treatment
- Fungal Infections and Studies
- Virology and Viral Diseases
- Chronic Lymphocytic Leukemia Research
- Vaccine Coverage and Hesitancy
- Drug-Induced Adverse Reactions
Centre Hospitalier Universitaire de Nantes
2018-2023
Centre d'Immunologie et des Maladies Infectieuses
2022
Institut Pasteur
2021
Inserm
2010-2020
Université de Montpellier
2019
Institut de Recherche pour le Développement
2019
Agropolis International
2019
Recherches Translationnelles sur le VIH et les Maladies Infectieuses
2019
Bordeaux Population Health
2010
Since 2016, French guidelines have recommended the single-tablet regimen of tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC)/rilpivirine (RPV) as HIV post-exposure prophylaxis (PEP), but few data support this usage. We evaluated tolerability, treatment completion and occurrence seroconversion associated with combination in occupational non-occupational PEP.We conducted an observational, prospective, multicentre, open-label, non-randomized study five centres. Adults requiring PEP...
Abstract Beyond virological suppression and immunologic recovery, the objective of long‐term antiretroviral therapy is to suppress maximally viremia control for persistent immune activation. Non‐nucleoside reverse transcriptase inhibitor (NNRTI)‐containing regimens are associated with lower residual viremia. The study was evaluate impact long term NNRTI‐containing treatment on monocyte activation in a cohort patients infected HIV‐1. To identify factors viremia, adult HIV nevirapine or...
Tenofovir may be associated with nephrotoxicity. Several studies have shown that an early increase in urinary neutrophil gelatinase-associated lipocalin (NGAL) predict the occurrence of acute kidney injury. We investigated urine and plasma NGAL patients on long-term treatment nevirapine either tenofovir/emtricitabine or abacavir/lamivudine. studied 40 virologically controlled Caucasian stable (median >4 years) + (n = 20) abacavir/lamivudine 20), no history disease, high blood pressure...
Aims Polypharmacy increase the risk of drug–drug interactions (DDIs) in elderly population living with human immunodeficiency virus (HIV). Several expert databases can be used to evaluate DDIs. The aim study was describe actual DDIs between antiretroviral drugs and comedications an compare grading 3 databases. Methods All treatments HIV‐infected subjects aged 65 years older were collected 6 French HIV centres. Summary Product Characteristic (SPC), DDI Thesaurus (THES), Liverpool website...
Abstract In France, antiretroviral (ARV) treatment can be dispensed by hospital and/or community pharmacies. Since January 2016, an online patient medication file used to optimize dispensing, but interviews have not yet been incorporated into this system. To understand both people living with HIV (PLHIV) and their pharmacists’ habits expectations of interviews, two consecutive national surveys were organized. The first one, carried out in October 2016 care centers, was anonymous...
Objective: Widespread use of the measles vaccine should lead to elimination this disease. Here, we study seroprevalence in a cohort adults living with HIV born after introduction France and attempt identify risk factors for absence serum antibody. Design: In multi-centre cross-sectional study, adult outpatients 1980 were screened presence IgG Demographic clinical data obtained from standardized electronic medical record system. Univariate multivariate logistic regressions performed...
Abstract Background In the general population, sport activity is associated with better health and self-esteem. Among people living HIV (PLHIV), could also be The main objective of our study was to assess association between self-esteem among HIV. secondary objectives were evaluate associations fatigue as well pain. Methods We performed a cross-sectional observational PLHIV in region (Pays de la Loire France). Each adult seen routine care invited participate study. Participants fill out...
ObjectivesTo know the habits and expectations of people living with HIV (PLWH) face to their pharmacist.
Among 34,351 patients living with human immunodeficiency virus available HLA-B*57:01 included in the Dat'AIDS cohort, 194 (0.56%) had a history of progressive multifocal leukoencephalopathy (PML) and 1,746 (5.08%) were carriers HLA-B*57:01. The frequency was similar among PML compared without (6.19% [95% confidence interval, CI 2.8%-9.6%] vs. 5.08% 4.8%-5.3%];