A5021336607- Radioactivity and Radon Measurements
- Radioactive contamination and transfer
- Risk Perception and Management
- Nuclear and radioactivity studies
- Carcinogens and Genotoxicity Assessment
- Radiation Dose and Imaging
- Drug-Induced Hepatotoxicity and Protection
- HIV/AIDS drug development and treatment
- Radiation Detection and Scintillator Technologies
- Retinal Diseases and Treatments
- Building Energy and Comfort Optimization
- Geochemistry and Elemental Analysis
- Ubiquitin and proteasome pathways
- Geoscience and Mining Technology
- Hepatitis B Virus Studies
- DNA Repair Mechanisms
- Risk and Safety Analysis
- Effects and risks of endocrine disrupting chemicals
- Marine and Coastal Research
- Air Quality Monitoring and Forecasting
- Iterative Learning Control Systems
- Radiomics and Machine Learning in Medical Imaging
- Ferroptosis and cancer prognosis
- Climate Change and Health Impacts
- Retinal Imaging and Analysis
Zhejiang Center for Disease Control and Prevention
2010-2025
Dalian Municipal Central Hospital
2022
Zhejiang University
2009-2011
Objective Assess the level of radiation-related knowledge (RRK) and nuclear energy-related (NERK) among residents near Sanmen Nuclear Power Plant, first project adopted Advanced Passive Pressurized Water Reactor (AP1000) technology. Methods In this study, respondents were selected using stratified multi-stage random sampling for aged 18 years above living within 30 kilometers Station. Respondents surveyed face-to-face by investigators who received standardized training. The results survey...
Abstract Recent studies showed that hydrogen can be used as an effective radioprotective agent through scavenging free radicals. This study was undertaken to evaluate the effects of on immune system in mice. H 2 dissolved physiological saline using apparatus produced by our department. Spleen index and histological analysis were splenic structural damage. superoxide dismutase, GSH , MDA measured appraise antioxidant capacity a DCF assay for measurement radical oxygen species. Cell apoptosis...
Abstract To evaluate the impact of Qinshan Nuclear Power Plant (Qinshan NPP) in normal operation on surrounding environment and population, radioactivity levels drinking water ambient environment, as well residents’ cancer incidence, were continuously monitored for a period 9 years (2012–2020). All gross α β concentrations less than WHO recommended values (0.5 Bq/L 1 ). The results accumulated dose by thermoluminescent dosimeters (TLDs) indicated that radioactive level around NPP is...
The autoregressive integrated moving average with exogenous regressors (ARIMAX) modeling studies of pulmonary tuberculosis (PTB) are still rare. This study aims to explore whether incorporating air pollution and meteorological factors can improve the performance a time series model in predicting PTB. We collected monthly incidence PTB, records six pollutants Ningbo China from January 2015 December 2019. Then, we constructed ARIMA, univariate ARIMAX, multivariate ARIMAX models. incorporated...
Background Artificial intelligence (AI), which has been used to diagnose diabetic retinopathy (DR), may impact future medical and ophthalmic practices. Therefore, this study explored AI’s general applications research frontiers in the detection gradation of DR. Methods Citation data were obtained from Web Science Core Collection database (WoSCC) assess application AI diagnosing DR literature published January 1, 2012, June 30, 2022. These processed by CiteSpace 6.1.R3 software. Results...
Abstract Environmental radioactivity monitoring in the surroundings of nuclear facilities is important to provide baseline data for effective detection case any radioactive release region. In this work, we report first time long-term 137 Cs and 90 Sr environmental food samples around Qinshan power plant 2012–2019. The distribution levels, temporal variations source terms investigated were discussed. annual dose ( AED ) local population from ingestion foods was also evaluated. Peak values...
Introduction Sanmen nuclear power plant (SNPP) operates the first advanced passive (AP1000) unit in China. Methods To assess radiological impacts of SNPP operation on surrounding environment and public health, annual effective dose ( AED ) excess risk ER were estimated based continuous radioactivity monitoring drinking water ambient before after its during 2014–2021. In addition, residents' cancer incidence was further analyzed through authorized health data collection. Results The results...
Objectives Radioactivity monitoring around nuclear facilities is crucial to provide important baseline data for effective detection of radioactive leakage the environment. We aim establish a study levels 90 Sr and 137 Cs Sammen Nuclear Power Plant (SNPP) assess their associated health impact on surrounding residents. Methods In this study, we collected water food samples SNPP from 2011 2020 determined activity concentrations. statistically analyzed temporal trends evaluated radiation...
There were few studies reported the temporal trend of radioactivity in water and food. Here, using Hangzhou (Zhejiang, China) as a case study, we determined (90Sr, 137Cs, gross alpha, beta) levels variations food samples during 2012–2019, meanwhile 137Cs/90Sr activity ratios calculated dose assessment was performed. Results showed that 90Sr 137Cs concentrations varied from (1.6–17.2) × 10−3 (0.66–15.1) Bq/L, respectively. The alpha beta small, except those for Qiantang River. Radioactivity...
Objective To investigate the apoptosis-inducing effect of DMF on human liver cells (HL-7702) in vitro.Methods Liver were exposed to different concentrations (0,50,100,150,200 mmol/L)for 12 hours.Apoptotic rate,the expression Bax,Bcl-2 and Caspase-3 measured by FCM western blotting respectively.Resuits The increase apoptotic rate hepatocytes concentration-manner was shown after treatment for h.After Bcl-2 decreased steadily lower than control group(P＜0.01),the Bax showed no significant...
Objective To investigate the contents of radionuclide 137Cs in seafood from coastal areas Zhejiang province, and to estimate annual committed effective dose population different regions ingestion seafood. Methods Three representative monitoring were set on coastaline locally popular seafoods selected as objectives. The detected using HPGe γ spectrometry. doses estimated based results consumption data Zhejiang. Results The detection ratio produced province was be 35.3% (36/102)....
Objective To establish a rapid, high-efficiency and clean way to monitor pretreat the radioactivity in foods. Methods Food samples, 20 kg each of cabbage, crucian, shrimp, pork L milk, were collected around Qinshan nuclear power plant, totaling 10 samples for food. Each type foods was arranged two groups with samples. Samples pretreated using traditional ashing method (TAM) microwave (WAM) separately. HDEHP used 90Sr separation measurement. Calculations made time spent on food...
Objective: Follow-up observation of radiation accident in which a worker developed acute disease and eventually died leukemia. The case provided key practical information for the study on clinical effects health workers. Case Presentation: We observed followed-up progression effect exposure at various stages 28-year-old male patient. examined chromosomal morphology, white blood cell count, sperm count. Laboratory tests leukemia diagnosis other parameters were performed. Results: After...
Objectives Model prediction of radioactivity levels around nuclear facilities is a useful tool for assessing human health risks and environmental impacts. We aim to develop model forecasting in the environment food world’s first AP 1000 power unit. Methods In this work, we report pilot study using time-series monitoring data establish Autoregressive Integrated Moving Average (ARIMA) models predicting levels. The were screened by Bayesian Information Criterion (BIC), accuracy was evaluated...
Baseline study on environmental radioactivity levels and public health conditions are crucial before the operation of nuclear facilities. Our goal is to establish a baseline database San'ao Nuclear Power Plant (SNPP). To achieve this, water food samples collection was carried out around SNPP from 2021 2022 for laboratory analysis determine levels. Thereafter, annual effective dose (AED) local residents were evaluated by results cancer incidence rates analyzed data residents. showed that...
Objective To study DNA damage of workers occupationally exposed to lead with flow cytometer assay. Methods The lymphocytes were obtained from 41 (comparable group) and another 50 control group. Flow (FCM) assay was used detect damage. Results rate geometric mean fluorescence intensity in the comparable group significantly higher than those (P 0.05). differences correlation analysis between blood lead, urine lead,8-ALA not significant (P>0.05). showed no statistical significance concentration...
Objective To investigate the concentrations of indoor radon (222Rn) and its daughter products as well thoron (220Rn) in selected houses Yuhang district Sanmen county,Zhejiang province,and estimate their annual effective doses to population.Methods Solid state nuclear track detectors were used dwellings county,and placed bedrooms or living rooms.Without changing ventilation habits residents,These continuously from March September 2009.Results Indoor 222 Rn 220Rn low-rise buildings highest...
目的 探讨不同染毒剂量二甲基甲酰胺(DMF)在不同染毒时间下对人正常离体肝细胞DNA损伤的影响.方法 肝细胞染毒分别以PBS阴性对照组、1.56、6.25、25.00、100.00 mmol/L的DMF和100μmol/L的H2O2,染毒时间为0.5、3.0、6.0、12.0和24.0 h,用γH2AX免疫荧光法观察肝细胞DNA的损伤情况.结果 不同剂量的DMF和H2O2诱导形成γH2AX焦点的细胞数量多于PBS阴性组,差异有统计学意义(P＜0.01),并且随着DMF染毒剂量的增加,形成γH2AX焦点细胞数有增多趋势;在不同染毒时间处理后,γH2AX焦点细胞数的形成除3.0 h组和0.5 h组比较,差异无统计学意义(P＞0.05),余处理时间组与0.5 h比较,差异均有统计学意义(P＜0.01),并且形成γH2AX焦点细胞数有减少趋势.结论 不同剂量DMF可引起DNA的损伤,并且损伤程度与剂量呈正相关,与染毒时间呈负相关,γH2AX可作为检测细胞DNA损伤程度的良好指标。
目的调查分析三门核电站运行前后，三门核电站周围生活饮用水中总放射性及食品中90Sr的放射性水平。 方法在2012-2019年，选取三门核电站周围7个生活饮用水监测点，分别采集丰水期和枯水期的水源水、出厂水、末梢水，测定分析水中总α、总β放射性水平；结合当地居民饮食习惯，采集三门当地出产的谷类、青菜、淡水鱼、海鱼等4种食品，测定分析其中的90Sr放射性水平。 结果三门核电站运行前，核电站周围生活饮用水中总α、总β放射性活度浓度范围为0.001~0.063 Bq/L和0.019~0.210 Bq/L；运行后，总α、总β放射性活度浓度范围为0.001~0.084 Bq/L、0.025~0.079 Bq/L，均低于《生活饮用水卫生标准》（GB 5749-2006）国家标准指导值。丰水期和枯水期的水源水、出厂水、末梢水中总α、总β放射性水平未见明显变化。运行前，4类食品90Sr放射性活度浓度范围为0.037~1.216 Bq/kg，运行后为0.049~0.692 Bq/kg，均低于《食品中放射性物质限制浓度标准》（GB 14882-94）指导值。...
目的调查分析2015—2019年三门核电站周围近海海域海水与海产品中90Sr放射性水平，估算食入海产品所致年待积有效剂量。 方法2015—2019年，在近海海域采集海水样品，并结合当地居民饮食习惯，采集三门当地3类常见海产品，测定分析90Sr放射性水平，结合浙江省沿海地区居民海产品消费量估算人群年待积有效剂量。 结果2015—2019年，三门核电站近海海域海水中90Sr放射性活度浓度范围为2.4~4.1 mBq/L，处于本底水平；3种海产品90Sr放射性活度浓度范围为6.7×10-2~1.3 Bq/kg（鲜重），均低于《食品中放射性物质限制浓度标准》（GB 14882-94）指导值。三门县居民食用海产品摄入90Sr所致年待积有效剂量为2.2×10-4~4.2×10-4 mSv，远低于全球内照射所致年待积有效剂量。 结论2015—2019年期间三门核电站周围海水及海产品中90Sr放射性水平平稳，人群剂量负担轻微。