Revascularization therapy is the mainstay of treatment in management myocardial infarction normal and diabetic patients. We attempted to evaluate cardioprotective actions quercetin rutin ischaemia-reperfusion-induced both rats.Myocardial infarct size was measured using staining agent 2,3,5-triphenyltetrazoliumchloride. Serum tissue malondialdehyde levels superoxide dismutase catalase heart were estimated spectrophotometrically. A lead II electrocardiogram monitored at various intervals...

Abstract Objectives Revascularization therapy is the mainstay of treatment in management myocardial infarction normal and diabetic patients. We attempted to evaluate cardioprotective actions quercetin rutin ischaemia-reperfusion-induced both rats. Methods Myocardial infarct size was measured using staining agent 2,3,5-triphenyltetrazoliumchloride. Serum tissue malondialdehyde levels superoxide dismutase catalase heart were estimated spectrophotometrically. A lead II electrocardiogram...

The objective of this study was to examine the neuroprotective effect resveratrol on cognitive impairment induced by scopolamine, a muscarinic antagonist, in rats. Memory administration scopolamine (1 mg/kg) intraperitoneally. Cognitive functions were assessed using radial arm maze, an active avoidance paradigm. Oxidative stress parameters like malondialdehyde, catalase and superoxide dismutase acetylcholinesterase activity estimated. More working reference memory errors maze test fewer...

Purpose: To evaluate the antidiabetic, antihyperlipidemic and antioxidant activities of Buchanania lanzan.Methods: Wistar rats were divided into nine groups six animals each, 40 mg/kg streptozotocin or + nicotinamide was administered intraperitonially to induce types I II diabetes. Those with blood glucose levels > 190 ± 8 mg/dl methanol leaf extract lanzan (MEBL, 100 200 mg/kg, p.o.) positive control for 21 days. Blood glucose, lipid profile, enzymes oxidative stress markers...

Herbal products from Ayurveda were always in the forefront providing leads to new drug discovery. Triphala, an ancient Ayurvedic herbal formulation comprises of equal portions Amalaki, Bibhitaki and Haritaki is used extensively for constipation, as anti-inflammatory, analgesic, anti-arthritic, hypoglycemic anti-aging agent.To evaluate effect Triphala on dextran sulphate sodium induced colitis rats.Present study carried out total five groups (n = 6 each group); first group served normal,...

Aim: The aim of this study was to investigate the protective effects bioflavonoid compounds i.e. rutin and naringin on gentamycin induced testicular oxidative stress in rats. Method: A total 42 male wistar albino rats were divided 7 groups, each contains 6 Gentamycin, 5 mg/kg, I.P administered from day 1 10. Rutin given different doses (5mg/kg, 10/kg) for a period 35 days treated animals. sham control group animals with water, vehicle 0.1% sod CMC also maintained until completion days. On...

Background and Aim: The drug Fucus vesiculosus is used in alternative system of medicine homoeopathy, for the treatment obesity. But homoeopathic literature survey, we found no substantial pharmacological evidence to prove its safety efficacy. So, study was taken up on this evaluated it different animal models (diet-induced chemical-induced models) Material Methods: Obesity induced adult female Wistar albino rats (100-120 g) by feeding with cafeteria diet 42 days diet-induced model...

A BSTRACT The pharmaceutical sector is experiencing rapid advancements in drug discovery, strict regulations, and a commitment to patient safety. This has led an increased demand for skilled pharmacovigilance experts who can ensure the safety effectiveness of medicinal products. Several factors contribute this demand. expanding landscape leads need thorough investigation profile new medications treatments. increasing volume products also requires close monitoring efficacy. Strict regulatory...

ObjectivesRevascularization therapy is the mainstay of treatment in management myocardial infarction normal and diabetic patients. We attempted to evaluate cardioprotective actions quercetin rutin ischaemia-reperfusion-induced both rats.

Aim: The aim of the study is to evaluate oxidant and antioxidant balance in experimentally induced testicular injury by ischemia reperfusion rats with different time intervals torsion/detorsion spermatic cord. Method: Male were divided into thirteen groups each group containing six rats. All subjected right cord torsion followed detorsion for except sham control group. Result: Malondialdehyde, super oxide dismutase, catalase levels estimated tissue rat. Spermatic torsion/ a significant...

Gossypium herbaceum commonly known as cotton plant cultivated world over and the main produce is used by textile industries. Other parts of this including leaves can also be explored for their best utilization, hence in direction we have evaluated efficacy leaf extract against an inflammatory condition i.e rheumatoid arthritis. Freund’s complete adjuvant (FCA) induced arthritis model was selected study and. All rats received treatments from 10th day induction continued up to 28 days study....