A5085183433- Ovarian function and disorders
- Reproductive Biology and Fertility
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Stress Responses and Cortisol
- Endometrial and Cervical Cancer Treatments
- Estrogen and related hormone effects
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and preeclampsia studies
- Ovarian cancer diagnosis and treatment
- Maternal and fetal healthcare
- Cervical Cancer and HPV Research
- Hemoglobinopathies and Related Disorders
- Reproductive System and Pregnancy
- Maternal and Perinatal Health Interventions
- Hormonal Regulation and Hypertension
- Hormonal and reproductive studies
- Pelvic floor disorders treatments
- Ectopic Pregnancy Diagnosis and Management
- Neuroendocrine regulation and behavior
- Maternal Mental Health During Pregnancy and Postpartum
- Menopause: Health Impacts and Treatments
- Gestational Diabetes Research and Management
- Birth, Development, and Health
University of Catania
2016-2025
Policlinico Universitario di Catania
2013
Brown University
1995-2004
University of Pisa
1995-2003
University of L'Aquila
1997-2003
University of Siena
2002
University of Modena and Reggio Emilia
1994-1995
Massachusetts General Hospital
1993
Allopregnanolone is a neuroactive steroid involved in modulating behavioral functions, stress, and neuroendocrine axes rats. Changes plasma allopregnanolone levels throughout the menstrual cycle have been reported healthy women, but there exists no information on possible gender or age-related changes source(s) of circulating allopregnanolone. The aim present study was to assess serum concentrations according gender, cycle, age, menopause normal men women; progesterone (P)...
Problem Chronic endometritis ( CE ) is a poorly investigated and probably underestimated pathology, which may cause abnormal uterine bleeding AUB ), pain, reproductive failures. Due to undefined symptoms the normal presence of leukocytes in endometrial mucosa, diagnosis be missed. Fluid hysteroscopy reliable technique for diagnosing this pathology. Few data exist on biochemical paracrine alterations that occur endometrium women diagnosed with . The aim study was find molecular modification...
The neurosteroid allopregnanolone has been shown to be a potent ligand of gamma-aminobutyric acid (GABA)-A receptors and enhances its receptor-mediated inhibitory events. Since central GABA plays major role, via GABA-A receptors, in hypothalamic–pituitary–adrenal (HPA) function rats, the present study evaluated effect passive immunoneutralization on diurnal changes corticosterone secretion acute stress-induced rats.In first protocol, four groups male rats (prepubertal, fertile, castrated...
The present study investigated the effect of allopregnanolone (5 alpha-pregnan-3 alpha-ol-20-one) or passive immunoneutralization brain allopregnanolone, most potent steroid produced by neurons, on ovulation rate and sexual behavior in female rats. Allopregnanolone was injected intracerebroventricularly rats diestrus proestrus tests were done estrus. intracerebroventricular injection significantly decreased number oocytes collected estrus (p < 0.01). To support a physiological involvement,...
Myo-inositol (MI) is a precursor for the synthesis of phosphatidylinositol polyphosphates (PIPs). The aim study to evaluate effect its administration on semen parameters male patients undergoing an in vitro fertilization cycles.In vivo study. Samples were 62 divided into three different groups: healthy fertile (Group A); with oligoasthenospermia (OA) B); control group (CTR). collected samples analyzed by optic microscopy order semen's volume, spermatozoa's number and motility before after...
Polycystic ovary syndrome is a complex disease characterized by various endocrine disorders that are the potential cause of anovulation and hyperandrogenism. Anti-Müllerian hormone expression suspected to be overexpressed in PCOS granulosa cells. AMH acts as regulator folliculogenesis: it produced cells follicles from stage primary follicle initial formation antrum. Serum intrafollicular levels elevated patients with due increased number small an secretion within each these follicles. This...
The oral transmission of HPV and, consequently, the risk cancer has increased in last years. Oral sex often been implicated among factors for infections, however, there is still no consensus on these topics, nor relationship between genital and infections. present study aimed to evaluate coexistence papilloma virus, at levels mucosa, women with a histologically confirmed lesions (and positive test) level negative control group. We also evaluated how some factors, such as smoking, number...
Hysteroscopy is considered not only a diagnostic instrument but also therapeutic tool for many uterine pathologies. In the early 1990s, advances in technology and techniques made hysteroscopy less painful invasive, allowing to increase number of gynecological procedures performed an ambulatory setting without significant patient discomfort with potentially cost savings. This so-called "office hysteroscopy" or "see-and-treat hysteroscopy", whose spread has permitted decrease operating room...
Hysteroscopy is the gold standard tool for endoscopic visualization of uterine cavity and it assesses a simultaneous detection treatment intracavitary anomalies with greater accuracy than other methods. The most common abnormalities, including endometrial polyps, submucosal myomas, septum intrauterine adhesions, are in infertile women. It object debate whether diagnostic and/or operative hysteroscopy should be considered basic work-up couples.
The uterine tourniquet is often not used to reduce intraoperative blood loss due controversial opinions in the literature. objective was evaluate effectiveness of this procedure laparotomic myomectomy. This a retrospective, monocentric case-control study, including patients who underwent myomectomy and were categorized into Tourniquet Group (A) No (B). outcomes compared. Intra-operative A 275 ± 200 mL, while B 410 390 mL (p = 0.11). Notably, five lost more than 1000 required transfusion, no...