Pasquale Klepp

ORCID: 0000-0002-0477-691X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Inflammatory Bowel Disease
  • Microscopic Colitis
  • Colorectal Cancer Screening and Detection
  • Genetic factors in colorectal cancer
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Helicobacter pylori-related gastroenterology studies
  • Colorectal Cancer Treatments and Studies
  • Gastric Cancer Management and Outcomes
  • Digestive system and related health
  • Liver Diseases and Immunity
  • Oral Health Pathology and Treatment
  • Oral microbiology and periodontitis research
  • Rheumatoid Arthritis Research and Therapies

Lovisenberg Diakonale Høgskole
2018-2023

University of Oslo
2014-2022

Lovisenberg Diakonale Sykehus
2013-2022

Oslo University Hospital
2018-2020

As mucosal healing is the goal of treatment in inflammatory bowel disease, defining a fecal [f-] calprotectin cut-off level for crucial. Previous studies have presented different levels. The aim this study was to investigate ability two f-calprotectin assays differentiate from inflammation ulcerative colitis.Sixty-two patients with colitis underwent colonoscopy classification [Mayo endoscopic subscore]. also submitted sample analysis using assays, Calpro ELISA and Buhlmann ELISA.The...

10.1093/ecco-jcc/jju015 article EN Journal of Crohn s and Colitis 2014-12-05

Objective The association between ulcerative colitis (UC) and colorectal cancer (CRC) is widely accepted, although attenuated risk has been reported in recent years. Colonoscopic surveillance recommended with intervals based on established clinical factors. Nevertheless, a significant number of patients develop interval cancers, indicating the need improved individualised assessment. In present study, we evaluated factors associated CRC during prescheduled follow-up 20 years after diagnosis,...

10.1136/bmjgast-2019-000361 article EN cc-by-nc BMJ Open Gastroenterology 2020-03-01

Background and aim: Colonoscopic surveillance is recommended in patients with longstanding inflammatory bowel disease (IBD) as they are at increased risk of colorectal cancer (CRC). Non-invasive may improve compliance access. Multi-target stool DNA (MT-sDNA) has been validated for screening sporadic CRC but not assessed IBD. Our aim was to assess the performance a MT-sDNA test real-life setting IBD.Material methods: A total 192 IBD enrolled from two prospective cohorts submitted an EDTA...

10.1080/00365521.2018.1424935 article EN Scandinavian Journal of Gastroenterology 2018-01-09

Background Inflammatory bowel disease, which includes ulcerative colitis (UC), is an inflammatory disorder with potential impact on periodontal but evidence to date for this association limited. The primary aim of study was investigate the prevalence periodontitis according 2017-classification in a cohort subjects UC. secondary assess correlation status previous UC disease parameters and oral health-related quality-of-life.Method A from community hospital Norway confirmed extensive...

10.1080/00016357.2023.2210660 article EN cc-by-nc-nd Acta Odontologica Scandinavica 2023-05-12

AIMTo evaluate the use of chromoendoscopy for surveillance ulcerative colitis in a real-life community hospital setting.

10.3748/wjg.v24.i35.4069 article EN cc-by-nc World Journal of Gastroenterology 2018-09-19

3607 Background: Surveillance for colorectal cancer (CRC) in inflammatory bowel disease (IBD) has so far not been effective. Mucosal or fecal biomarkers may be useful the selection of high risk patients. The yield depend on underlying carcinogenic pathway. In IBD associated CRC (IBD-CRC) distribution chromosomal instability (CIN) and microsatellite (MSI) is well documented. Our objective was to determine CIN MSI association clinico-histological factors a cohort patients with IBD-CRC....

10.1200/jco.2013.31.15_suppl.3607 article EN Journal of Clinical Oncology 2013-05-20

Abstract Background: Inflammatory bowel disease (IBD) includes the major diseases Crohn’s (CD) and ulcerative colitis (UC). IBD is understood to be an inflammatory systemic disorder that may have impact on periodontal through shared mechanisms. The two subtypes of are often described together although they differ with regards affected sites in gastrointestinal tract, histology oral manifestations. primary aim this study was investigate prevalence periodontitis a cohort UC according...

10.21203/rs.3.rs-1439796/v1 preprint EN cc-by Research Square (Research Square) 2022-03-16
Coming Soon ...