European and American investigators have reported response rates of 38% to 83% for ifosfamide alone in pretreated sarcomas. In a phase II trial 2.0g/m2 days 1 4 with mesna uroprotection 124 patients previously failed sarcomas, four (3%) responded completely (95% exact confidence interval, 1% 8%) 26 (21%) had complete or partial 14% 29%). The median time progression was 5 9 months responders, respectively. the subset soft tissue rate receiving bolus administration 26%, compared 9% continuous...

As an existential crisis, death anxiety may create suffering and impact quality of life. Based on a sample 101 patients (63 with AIDS 38 advanced cancer) 79 family caregivers (43 patients' 36 cancer caregivers), this study examined the that their relationship The results indicated expressed greater than patients, but was not different among caregivers. Both experienced Greater associated lower life, particularly in psychological domain for patients. There were significant correlations...

Background Obsessive-compulsive disorder (OCD) is a prevalent and impairing psychiatric that frequently misdiagnosed. Further, despite breadth of evidence in support Exposure Response Prevention (ERP) the treatment OCD, it often underutilized or used incorrectly.

These authors and the pages of this text...create blueprint that will build kind care system we all wish for our loved ones. - From Foreword by Betty Rolling Ferrell, RN, PhD, FAAN. The second edition award-winning text provides essential guide to achieving best practices in palliative nursing. It offers a blend holistic, spiritual, cultural, humanistic caring coupled with aggressive management pain symptoms associated advanced disease. With over 20 per cent book covering pharmacologic...

In Brief With symptoms as varied anger, short attention span, physical exhaustion, and a poor self-concept, burnout in nurses, especially those caring for dying patients, can result compromised patient care. The solution is simple but perhaps not easy: self-care. 13th series on palliative nursing

Background: Although various forms of psychoeducation and counseling interventions have been examined among patients with a variety diagnoses, the unique contribution phase-specific telephone (TC) to ongoing process adjustment has not explored breast cancer their partners. Objective: To conduct randomized controlled clinical trial evidence-based TC enhance emotional, physical, social adjustments in Methods: A purposive sample 249 patient-partner dyads were assigned randomly one four groups:...

There is growing recognition of the reciprocity suffering by patients and families experiencing terminal illness need to improve quality their lives as patient's progresses. Research presented that addresses importance a dyadic perspective in recognizing patients' families' stress adjustment related physical, emotional, social, spiritual financial needs at end-of-life. These aspects life are specifically addressed palliative care. The philosophy goals care described, its role promoting best...

Setting: A LISTSERV announcement posted on the SHARE Web site and purposeful recruitment of women known to be diagnosed treated for breast cancer.

Teaching loss, grief, and bereavement to nursing students should be an interactive process stimulate critical thinking address the affective domain of learning. Lecture as a teaching methodology may easiest prepare deliver; however, used alone, it is ineffective in identifying perceptions, fears, issues related dying death. Personal professional experiences are central student's learning effective compassionate care patient their family. Strategies that explore such allow move forward focus...

The End-of-Life Nursing Education Consortium (ELNEC) is a train-the-trainer educational program to help nursing faculty integrate care of the dying patient and patient's family in curriculum. authors describe ELNEC experience, which prepares nurse educators competently teach end-of-life care, provides them with necessary knowledge, skills, resources effectively content into existing curricula.

Abstract The effect of marital support and from other adults on the emotional physical adjustment 121 husbands women with breast cancer was examined. Role function satisfaction health care also were evaluated as predictors adjustment. Intact data series obtained at 7-10 days 1,2, 3,6, 12 months after surgery. Emotional could be predicted by patient's response to interactional needs adults. relationships significant concurrent times, across contiguous predictive day postsurgical period both...

Objective: Use Rogers'(1992) framework of the science unitary human beings to examine relationships among spirituality, perceived social support, death anxiety, and nurses'willingness care for AIDS patients. Design: Descriptive, correlational. Population, Sample, Setting: female RNs in New York City Metropolitan area who patients with AIDS. Convenience sample 220 worked eight hospitals either on AIDS‐dedicated units (n = 88), or medical‐surgical scatterbed 132) a daily patient census between...

Based on a longitudinal, quality-of-life study, this article presents pilot data regarding the spiritual well-being of patients with advanced cancer or AIDS and their family caregivers. Data include similarities differences between patient caregiver populations patient/family dyads as well trends regard to changes in during illness dying process. The reliability Spiritual Well-Being Scale was examined for groups, relationship selected demographic variables well-being. Implications practice...

Background: A basic tenet of palliative care is interprofessional collaboration. Palliative educators and practitioners lead the way in responding to Institute Medicine's (2003) challenge transform educational health systems through Through exemplary commitment collaboration, a college's academic leader, collaboration with Department Chairs Directors nursing allied professions, can illustrate analyze processes development simulated case study combat veteran traumatic brain injury. Methods:...

Background: Although definitions of palliative care include quality life as a central concern, little research has been published about both the patients with advanced illness and their family members, particularly changes in over time. Objectives: The aims this prospective longitudinal pilot study were to: (1) establish reliability multidimensional instruments based on acquired immune deficiency syndrome (AIDS) cancer caregivers; (2) identify differences between AIDS cancer, caregivers...

Despite the increasing public demand for enhanced care of older patients and those with life-threatening illness, health professionals have had limited formal education in geriatrics palliative care. Furthermore, interdisciplinary team training is limited. In order to remedy this situation, proactive interventions are being undertaken so that embedded within physicians, nurses, social workers, as well other associated members. This article discusses various educational approaches team-based...