A5090580011- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Nitric Oxide and Endothelin Effects
- Cardiac Arrest and Resuscitation
- Cardiovascular Disease and Adiposity
- Heart Failure Treatment and Management
- Intensive Care Unit Cognitive Disorders
- Neurological disorders and treatments
- Respiratory Support and Mechanisms
- Cardiovascular and exercise physiology
- Cardiac Structural Anomalies and Repair
- Cardiovascular Health and Disease Prevention
- Global Public Health Policies and Epidemiology
- Family and Patient Care in Intensive Care Units
- Heart Rate Variability and Autonomic Control
- Cardiac Valve Diseases and Treatments
- Sleep and Wakefulness Research
- Angiogenesis and VEGF in Cancer
- Sepsis Diagnosis and Treatment
- Eicosanoids and Hypertension Pharmacology
- Blood Pressure and Hypertension Studies
University of Tsukuba Hospital
2016-2022
University of Tsukuba
2011-2022
Ibaraki Prefectural University of Health Sciences
2014-2021
Satou Hospital
2018
National Center for Global Health and Medicine
2015
National Cerebral and Cardiovascular Center
2015
Institute of Clinical Research
2008
Yokosuka Kyosai Hospital
2005
This study examined the impact of cardiac resynchronization therapy (CRT) by triangle ventricular pacing (Tri-V) on left (LV) function and dyssynchrony. Twenty-one patients with NYHA class III or IV heart failure were studied. For Tri-V, two right (RV) leads connected to CRT device via a Y-connector one lead anchored at RV apex other outflow tract. The LV was positioned in posterolateral lateral vein. standard bi-ventricular (Bi-V) performed apical leads. assessed measurement positive dp/dt...
Previous studies have shown a relationship between delirium and depressive symptoms after cardiac surgery with distress personalities linking to negative surgical outcomes. The aim of the present study is further investigate association patients Type D (distressed) personality regards surgery. We conducted consecutive-sample observational cohort pilot an estimated 142 needed. Enrollment criteria included aged ≥18 years who were undergoing planned cardiovascular, thoracic abdominal artery...
Endothelin (ET)-1 is the best known potent vasoconstrictor and has been implicated in pathogenesis of sepsis-associated acute kidney injury (AKI) human or lipopolysaccharide (LPS)-induced AKI animal models. We have previously shown that ET-1 highly up-regulated renal tissues plasma after LPS administration. Here, we investigated whether landiolol hydrochloride, an ultra-short-acting beta-blocker, can play important role ameliorating levels LPS-induced up-regulation HIF-1α-ET-1 system...
Although an intraventricular filling delay has been observed in patients with a psuedonormalized transmitral flow pattern, little is known about the underlying hydrodynamic nature of this phenomenon. Methods: To examine those hydrodynamics, we studied every echocardiographic frame showing ventricular inflow (80 Hz) apical long‐axis view and M‐mode image using contrast echocardiography 29 pattern 26 normal controls. The velocity front (Vp), ratio Vp to E, mean radius vortices associated were...
Hyperinflation (HI) is performed following open endotracheal suctioning (OES), whose goals include: to stimulate a cough, recover oxygenation and improve compliance. However, it may also induce unintended consequences, including: lung stress strain, failure maintain high distending pressure, subsequently cycling recruitment derecruitment. Here, our aim was investigate the effects of hyperinflation after repeated OES on sequential alteration arterial injury profile using saline lavage-induced...
The World Health Organization included burnout syndrome criteria that reduce both professional quality of life and work satisfaction in its 11th Revision the International Classification Diseases 2019 while nursing bodies have issued action calls to prevent syndrome. Despite this, effect social factors, personality traits cross-interaction on is still unclear.To reveal association between ethical climate, personal trait life.An online survey registered nurses working adult, pediatric or...
Abstract Background Although endotracheal suctioning induces alveolar derecruitment during mechanical ventilation, it is not clear whether repeated exacerbates lung injuries. The present study aimed to determine open (OS) injury compared closed (CS) ventilation in an animal model of acute respiratory distress syndrome (ARDS). Methods Briefly, thirty six Japanese white rabbits were initially ventilated pressure-controlled mode with a constant tidal volume (6 mL/kg). Then, was induced by...
A growing body of evidence shows the cardiovascular benefits fish oil ingredients, including eicosapentaenoic acid (EPA), in humans and experimental animals. However, effects EPA on endothelin (ET)-1-induced cardiomyocyte hypertrophy involved signaling cascade are largely unknown. previous study has demonstrated that peroxisomal proliferator-activated receptor (PPAR)-α ligand (fenofibrate) prevents ET-1-induced hypertrophy. Although is a PPAR-α, to date, no examined relationship between...
A 27-year-old female nurse intravenously injected 5 mL of cigarette soakage solution that contained approximately 5.7 mg nicotine, in a suicidal attempt. Clinical manifestations consisted nausea, palpitation, abdominal pain, repeated vomiting, and diarrhea. She remained fully conscious during this episode. About 7 hours later, she visited emergency department on foot received fluid infusion for dehydration. recovered at night the day. This is first documented report acute nicotine poisoning...
Endothelin-1 (ET-1) is a mediator of various physiological and pathological processes, including vascular inflammation, cell proliferation vasoconstriction. Attenuation ET action using ET-1 antagonists reduces pulmonary leakage inflammation in several models lung injuries experimental acute respiratory distress syndrome (ARDS). Based on these earlier reports, the current study investigates patterns levels circulation tissues an model lavage-induced surfactant-depleted injury. Additionally,...
To examine validity and reliability of the Japanese version Cornell Assessment Pediatric Delirium.Prospective double-blinded observational cohort study.Eight-bed mixed PICU (post-surgical internal medicine) from May 2017 to June 2018.All children between ages 0-13 years who were admitted for at least 24 hours eligible inclusion, as long child was arousable verbal stimulation.Two nurses simultaneously independently assessed each patient pediatric delirium with Delirium; this compared gold...