A5033338032- Forensic Toxicology and Drug Analysis
- Poisoning and overdose treatments
- Restraint-Related Deaths
- Alcohol Consumption and Health Effects
- Soil and Water Nutrient Dynamics
- Cannabis and Cannabinoid Research
- Burn Injury Management and Outcomes
- Soil Carbon and Nitrogen Dynamics
- Heme Oxygenase-1 and Carbon Monoxide
- Anesthesia and Sedative Agents
- Forensic Entomology and Diptera Studies
- Antibiotics Pharmacokinetics and Efficacy
- Allelopathy and phytotoxic interactions
- Injury Epidemiology and Prevention
- Veterinary Pharmacology and Anesthesia
- Historical and Religious Studies of Rome
- Opioid Use Disorder Treatment
- Marine Toxins and Detection Methods
- Pesticide Exposure and Toxicity
- Bacterial Identification and Susceptibility Testing
- Tracheal and airway disorders
- Viral Infections and Vectors
- Groundwater and Isotope Geochemistry
- Transplantation: Methods and Outcomes
- Neurosurgical Procedures and Complications
University of Campania "Luigi Vanvitelli"
2008-2024
University of Naples Federico II
2007
Abstract An unusual case of poisoning by the ingestion oleander leaves is reported. A 71 year old male laboratory technician committed suicide at home in this manner. At death scene a steel pan and other paraphernalia, used for extraction oleandrin cardiac glycosides from Nerium plant were found. Toxicological investigations oleandrin, oleandrigenin, neritaloside, odoroside performed LC–MS/MS on all biological samples (peripheral blood, vitreous humor, urine, liver, gastric contents) yellow...
Plasma concentrations of dexmedetomidine (D = 0.1 mg/kg), midazolam (M 2 and butorphanol (B 0.4 mg/kg) were analyzed by liquid chromatography-mass spectrometry (LC-MS/MS) after their simultaneous (DMB) transnasal (TN) administration to healthy rabbits. Time-dependent changes in sedation antinociception evaluated measuring a score based on rabbit's posture, loss the righting, palpebral pedal withdrawal reflexes instrumental monitoring rectal temperature, heart rate, arterial blood pressure,...
It has been estimated that approximately one in seven of all global suicides is due to pesticide self-poisoning, mostly rural areas developing countries. Organophosphorus (OP) compounds are a group pesticides exerting their toxicological effects through non-reversible inhibition the enzyme acetylcholinesterase (AChE). Among these compounds, phorate (thimet) most dangerous use which restricted many A case intentional suicide after ingestion 24-year-old Bengali male described. This second...
Suicide by helium inhalation has become increasingly common in the last few decades Europe and US because it produces a quick painless death. Inhaled-gas suicides can easily be assessed through death scene investigation autopsy. However, is colorless odorless inert gas that unfortunately cannot detected using standard toxicological analysis. A successful analysis was performed following suicide of 17-year-old female. For detection helium, central/peripheral blood samples gaseous from...
Drug-facilitated sexual assault (DFSA) cases are pretty common in forensic toxicology. In this case report, a 56-year-old female tourist claimed to have been sexually assaulted by five men after having had drug-spiked alcoholic drink. Urine samples were collected at 38, 44 and 45 h the alleged rape. After 7 months, hair strands (28 cm length) also sampled perform segmental testing. The urine decontaminated segments tested for different groups of basic, acidic neutral substances...
Fire-related deaths are usually a consequence of carbon monoxide (CO) poisoning or shock from thermal injuries. In humans, high levels carboxyhemoglobin (COHb) concentrations in the blood can support diagnosis CO poisoning. veterinary medicine, few studies investigated pathological changes and COHb% fire victims, no data available on post-mortem gas composition due to fire. This study aims investigate COHb both animal victims cadavers experimentally exposed For this purpose, dogs were...
In complex suicides, more than one suicide method is applied at the same time or after other. The most common includes ingestion of drugs combined with drowning. A case acute intoxication by Bisoprolol and drowning reported. dead body a 40-year-old woman was discovered on river side, soon her husband found note home. woman’s vehicle four empty boxes Bisoprolol, widely used beta blocker, were also found. Main autopsy findings consistent represented plume froth mouth nostrils frothy fluid in...
The study regards n. 267 drug related deaths submitted to toxicological analyses for forensic purpose, since 2008 2012, at the Laboratory of Forensic Toxicology Second University Napoli (SUN), Italy. Among cases studied (94% males and 6% females) 13.1% foreign citizens.For each case autopsy findings all drugs detected were recorded. In addition other epidemiological data such as age, race, gender, place circumstance death also supplied. A systematic analysis (STA) illicit drug,...
Introduction: The human post-mortem microbiome (HPM) plays a major role in the decomposition process. Successional changes bacterial communities have been recently demonstrated using high throughput metagenomic sequencing techniques, showing great potential as interval (PMI) predictor. aim of this study is to verify application mass spectrometry technique, better known MALDI-TOF MS (matrix-assisted laser desorption/ionization time-of-flight spectrometry), cheap and quick method for microbe...
Chronic encapsulated intracerebral hematoma (CEIH) is a rare solid mass characterized by the presence of fibrotic capsule that can present variety signs and symptoms due to effect hydrocephalus. It may be caused post-traumatic or spontaneous bleeding as related an adjacent aneurysm, angiomas neoplasms. Differential diagnosis must applied in order for it mimic neoplasm vascular malformation. Several cases CEIH have been reported but only few them intraventricular localization. A forensic...
Choking is a type of asphyxia due to the internal obstruction airways by foreign material, quite always food. Most choking deaths are accidental and occur so quickly that may mimic heart attack. This scenario also known as "Cafè coronary syndrome" or "bolus death". At autopsy, pieces under-chewed food commonly lodged at, above, in tracheal space adjacent laryngeal inlet. In these fatal events mechanisms other than can be involved, such vasovagal episode (by stimulation autonomic nerve plexus...
The COVID-19 pandemic has consistently raised the number of drug seizures, in United States as Europe. also changed typology seizures from “more traditional” drugs to New Psychoactive Substances (NPSs), depending on geographical area. In Europe, most frequent NPSs are synthetic cannabinoids (SCs) and cathinones, nonetheless opioids phenethylamines widely used. aim study is detection NPS other substances abuse available black market, by quali/quantitative methods LC-MS/MS GC-MS. From 2018...
Alprazolam is a psychoactive triazolo-benzodiazepine, commonly prescribed for the treatment of anxiety disorders and considered safe due to its high therapeutic index. It frequently detected in polydrug-related deaths but there are very few cases fatal intoxication by alprazolam not combination with alcohol or other drugs. A poisoning 60-years old male physician has been reported. At autopsy, no evidence traumatic injuries diseases was observed except signs bronchopneumonia slight...