A5037799106- Muscle Physiology and Disorders
- Blood Coagulation and Thrombosis Mechanisms
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Cancer-related gene regulation
- Congenital heart defects research
- Cardiomyopathy and Myosin Studies
- Hemophilia Treatment and Research
- Liver Disease Diagnosis and Treatment
- Neurogenetic and Muscular Disorders Research
- Tissue Engineering and Regenerative Medicine
- Genetic factors in colorectal cancer
University Medical Center HCMC
2023
Ho Chi Minh City Medicine and Pharmacy University
2019-2021
Hanoi Medical University
2013
The accurate evaluation of liver fibrosis is crucial for the treatment and follow up chronic hepatitis B (CHB) patients. We examined efficiency serum Mac-2 Binding Protein Glycosylation isomer (M2BPGi) in diagnosing stages CHB A cross-sectional study was conducted on 177 adult patients visiting University Medical Center Ho Chi Minh City, Vietnam between October 2019 December 2021. M2BPGi, ARFI, APRI, FIB-4 were tested against FibroScan® sensitivity, specificity, positive predictive value...
Duchenne and Becker muscular dystrophies (DMD/BMD) are the most common inherited muscle diseases caused by mutations in dystrophin gene. The reading frame rule explains genotype-phenotype relationship DMD/BMD. In Vietnam, extensive mutation analysis has never been conducted Here, 152 Vietnamese dystrophy patients were examined for exon deletion amplifying 19 deletion-prone exons ends confirmed cDNA if necessary. result was that 82 (54%) found to have deletions, thus confirming exact ends. A...
Duchenne Muscular Dystrophy is an X-linked recessive disorder characterized by progressive muscular degeneration, patients often develop cardiac failure in the later stage and death occurs before 20 years of age. For a disease with poor postnatal prognosis such as (DMD), providing carrier mother option prenatal diagnosis subsequent pregnancy accepted practice many places where termination allowed. Though methods direct sequencing Sanger's has been widely used, Next-Generation Sequencing...
The aim of this study was to determine common variants in F8, including intron 22 inversion (Inv22), 1 (Inv1) and point mutations, the transmission these between patients with haemophilia A (HA) their family members.Genetic analysis conducted 71 who were clinically diagnosed HA 152 related female members South Vietnam by a combination PCR (I-PCR), multiplex direct sequencing.Variants Inv22, mutations (with 37 genotypes) two novel variants, occupied 60 HA. Among severe patients, rate Inv22...
Background Gardner’s syndrome is an autosomal dominant disorder with complete penetrance, caused by mutations in the adenomatous polyposis coli gene(APC gene). Gardner’s characterized intestinal polyposis, osteomas and dental abnormalities. APC are mostly point mutations, causing a truncated dysfunctional protein. Detection of gene from patient syndrome.