- Plant Molecular Biology Research
- Light effects on plants
- Photosynthetic Processes and Mechanisms
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Plant Reproductive Biology
- Gut microbiota and health
- Cerebrovascular and Carotid Artery Diseases
- Plant Gene Expression Analysis
- Probiotics and Fermented Foods
- Physics of Superconductivity and Magnetism
- Superconductivity in MgB2 and Alloys
- Moyamoya disease diagnosis and treatment
- Nitric Oxide and Endothelin Effects
- Plant Stress Responses and Tolerance
- Boron and Carbon Nanomaterials Research
- Cerebrospinal fluid and hydrocephalus
- Diamond and Carbon-based Materials Research
- Plant tissue culture and regeneration
- Vascular Malformations Diagnosis and Treatment
- Aortic Disease and Treatment Approaches
- Iron-based superconductors research
- Plant Virus Research Studies
- Metal and Thin Film Mechanics
- Meningioma and schwannoma management
National Institute of Advanced Industrial Science and Technology
2003-2024
University of Tsukuba
2003-2024
Asahi Breweries (Japan)
2016-2017
Kyushu University
1989-2013
Kyushu Dental University
2013
The Ohio State University
2008-2011
RIKEN Center for Sustainable Resource Science
2009
Japan Science and Technology Agency
2003
Tokyo University of Science
2001-2002
Megmilk Snow Brand (Japan)
2001
The circadian clock acts as the timekeeping mechanism in photoperiodism. In Arabidopsis thaliana, a clock-controlled flowering pathway comprising genes GIGANTEA (GI), CONSTANS (CO), and FLOWERING LOCUS T (FT) promotes specifically under long days. Within this pathway, GI regulates rhythms earlier hierarchy than CO FT, suggesting that might regulate indirectly by affecting control of rhythms. We studied relationship between roles using late elongated hypocotyl associated1 double mutants,...
Constituting approximately 10% of flowering plant species, orchids (Orchidaceae) display unique flower morphologies, possess an extraordinary diversity in lifestyle, and have successfully colonized almost every habitat on Earth. Here we report the draft genome sequence Apostasia shenzhenica, a representative one two genera that form sister lineage to rest Orchidaceae, providing reference for inferring content structure most recent common ancestor all extant improving our understanding their...
The circadian clock controls the period, phasing, and amplitude of processes that oscillate with a near 24-h rhythm. One core group components in Arabidopsis pace central oscillator is comprised five PRR (pseudo-response regulator) proteins whose biochemical function remains unclear. Peak expression TOC1 (timing cab 1)/PRR1, PRR3, PRR5, PRR7, PRR9 are each phased differently over course day loss any protein alters period. Here we show that, together TOC1, PRR5 only other likely proteolytic...
Abstract Endoreduplication involves a doubling of chromosomal DNA without corresponding cell division. In plants, many types transit from the mitotic cycle to endoreduplication or endocycle, and this transition is often coupled with initiation expansion differentiation. Although number regulators implicated in endocycle onset have been identified, it still largely unknown how developmentally regulated at whole organ level. Here, we report that nuclear-localized SUMO E3 ligase, HIGH PLOIDY2...
Abstract The floral regulators GIGANTEA (GI), CONSTANS (CO), and FLOWERING LOCUS T (FT) play key roles in the photoperiodic flowering responses of long-day plant Arabidopsis thaliana. GI-CO-FT pathway is highly conserved plants. Here, we demonstrate that circadian clock proteins LATE ELONGATED HYPOCOTYL (LHY) CIRCADIAN CLOCK–ASSOCIATED1 (CCA1) not only repressed transition under short-day conditions but also accelerated when plants were grown continuous light (LL). LHY CCA1 LL by promoting...
In plants, basic helix-loop-helix (bHLH) transcription factors play important roles in the control of cell elongation. Two bHLH proteins, PACLOBTRAZOL RESISTANCE1 (PRE1) and Arabidopsis ILI1 binding bHLH1 (IBH1), antagonistically regulate elongation response to brassinosteroid gibberellin signaling, but detailed molecular mechanisms by which these remain unclear. Here, we identify transcriptional activators for (ACEs) demonstrate that PRE1, IBH1, ACEs constitute a triantagonistic system...
To confirm the stress‐relieving effects of heat‐inactivated, enteric‐colonizing Lactobacillus gasseri CP2305 (paraprobiotic CP2305) in medical students taking a cadaver dissection course. Healthy (21 males and 11 females) took paraprobiotic daily for 5 weeks during The General Health Questionnaire Pittsburgh Sleep Quality Index were employed to assess stress‐related somatic symptoms sleep quality respectively. aggravation stress‐associated was observed female (P = 0·029). improved group...
The effect of subarachnoid hemorrhage (SAH) on endothelium-dependent vasodilation isolated rabbit basilar artery was examined using an isometric tension recording method. Thirty-five rabbits that had 2 successive blood injections were divided into 3 groups: normal animals (control), 4 days, and weeks after the first SAH. Acetylcholine (ACh) (10(-6)-10(-4) M) adenosine triphosphate (ATP) used to evoke dose-dependent arterial rings previously contracted by 10(-6) M serotonin. In killed days...
The autoregulatory loops of the circadian clock consist feedback regulation transcription/translation circuits but also require finely coordinated cytoplasmic and nuclear proteostasis. Although protein degradation is important to establish steady-state levels, maturation into their active conformation factors homeostasis. HSP90 facilitates a wide range client proteins, studies in metazoan clocks implicate as an integrator input or output. Here we show that Arabidopsis clock-associated F-box...
Plants adapt to abiotic and biotic stresses by activating abscisic acid-mediated (ABA) stress-responsive salicylic acid-(SA) or jasmonic (JA) pathways, respectively. Although the pathway interacts antagonistically with mechanisms that regulate these pathways remain largely unknown. In this study, we provide insight into function of vascular plant one-zinc-finger proteins (VOZs) modulate various stress responses in Arabidopsis. The expression many genes was changed voz1voz2 double mutant...
Chemical priming has emerged as a promising area in agricultural research. Our previous studies have demonstrated that pretreatment with low concentration of ethanol enhances abiotic stress tolerance Arabidopsis and cassava. Here, we show treatment induces heat tomato ( Solanum lycopersicon L.) plants. Seedlings the cultivar ‘Micro-Tom’ were pretreated solution then subjected to stress. The survival rates ethanol-pretreated plants significantly higher than those water-treated control...
A straightforward and cheap method for creating extended defects, strong pinning centers, in superconducting thin films is proposed. Clearly, by very short time (3–5 s) rf sputtering at suitable substrate temperatures, we deposited Ag nanodots on SrTiO3 substrates prior to the growth of films. The were studied atomic force microscopy. Due lattice mismatch and/or chemical poisoning, top phase does not form, this way effective centers which increase critical current density film. was applied...
We have examined the competitive binding of several species Bifidobacterium and Escherichia coli Pb176, an enterotoxigenic E. (ETEC) strain, to gangliotetraosylceramide (asialo GM1 or GA1), a common bacterium-binding structure, identified factor(s) in culture supernatant fluid that inhibits Pb176 GA1. The ETEC strain we used expresses colonization factor antigen (CFA) II, which consists surface-associated antigens CS1 CS3. Competitive exclusion from GA1 molecules by cells was found vitro...
To investigate the fate of a streptomycin-rifampicin-resistant variant Lactobacillus gasseri SBT2055 (LG2055SR) and influence its oral administration on composition metabolism intestinal microflora.Intestinal passage LG2055SR was monitored by combination selection with antibiotics identification randomly amplified polymorphic DNA (RAPD)-PCR METHOD: Composition microflora analysed method developed Mitsuoka et al. (1965, 1974). Establishment orally-administered in human intestine confirmed...
The NAM, ATAF1/2, and CUC2 (NAC) domain transcription factor VND-INTERACTING2 (VNI2) negatively regulates xylem vessel formation by interacting with another NAC factor, VASCULAR-RELATED NAC-DOMAIN7 (VND7), a master regulator of formation. Here, we screened proteins VNI2 using yeast two-hybrid assay isolated two factors,
• Circadian clock proteins play key roles in adaptations of plants to diurnal environmental conditions. The photoperiodic flowering response is one the mechanisms adaptation seasonal changes lengths day and night. Double mutations two genes, LATE ELONGATED HYPOCOTYL (LHY) CIRCADIAN CLOCK ASSOCIATED 1 (CCA1), accelerated under short days (SDs) but delayed continuous light (LL) Arabidopsis thaliana. mechanism underlying late lhy;cca1 mutants LL was investigated here. Late with overexpression...
To clarify the effects of Lactobacillus gasseri CP2305 (CP2305) on quality life and clinical symptoms its functional mechanisms in patients with irritable bowel syndrome (IBS). After were administered daily for 4 weeks, IBS‐severity index score was significantly improved compared that placebo group, this improvement accompanied by a reduction health‐related worry changes intestinal microbiota. The gene expression profiling peripheral blood leucocytes showed treatment up‐regulated genes...
Journal Article Intestinal transit of an orally administered streptomycin–rifampicin‐resistant variant Bifidobacterium longum SBT2928: its long‐term survival and effect on the intestinal microflora metabolism Get access S. Fujiwara, Fujiwara Technology Research Institute, Snow Band Milk Products Co. Ltd, Kawagoe, Saitama, Japan Search for other works by this author on: Oxford Academic Google Scholar Y. Seto, Seto A. Kimura, Kimura H. Hashiba Applied Microbiology, Volume 90, Issue 1, 1...
Photoperiodic control of flowering is regulated by light and a circadian clock. Feedback regulation the transcription clock components one most common important mechanisms that functions in animals, fungi, plants. The Arabidopsis believed to involve two myb‐related proteins, LHY (late elongated hypocotyl) CCA1 (circadian associated 1), which negatively regulate TOC1 ( timing cab expression 1 ) gene through direct binding promoter. PIF3 (phytochrome‐interacting factor 3), bHLH binds promoter...