A5051585731- Radiology practices and education
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Healthcare cost, quality, practices
- Cancer Mechanisms and Therapy
- Health Systems, Economic Evaluations, Quality of Life
- Synthesis and biological activity
- Health Literacy and Information Accessibility
- Social Media in Health Education
- Patient-Provider Communication in Healthcare
- Healthcare Policy and Management
- Healthcare Quality and Management
- Synthesis and Characterization of Heterocyclic Compounds
- Global Health Workforce Issues
- MicroRNA in disease regulation
- Patient Satisfaction in Healthcare
- Innovations in Medical Education
- Diversity and Career in Medicine
- Meta-analysis and systematic reviews
- Healthcare Systems and Technology
- COVID-19 and healthcare impacts
- Medical Imaging Techniques and Applications
- Medical Malpractice and Liability Issues
- Protein Degradation and Inhibitors
- Patient Safety and Medication Errors
Beth Israel Deaconess Medical Center
2018-2025
Harvard University
2019-2025
Harvard University Press
2024
Hamilton General Hospital
2023
McMaster University
2023
Brookline Public Schools
2020
Augusta University
2007-2018
Augusta University Health
2011-2016
Queensland Rail
2013
Westchester Medical Center
1996
This study identifies macroautophagy as a key mechanism of cell survival in estrogen receptor-positive (ER+) breast cancer cells undergoing treatment with 4-hydroxytamoxifen (4-OHT). selective ER modifier is an active metabolite tamoxifen commonly used for the cancer. Our provides following findings: (a) only 20% to 25% treated 4-OHT vitro die via caspase-dependent death; more typically, antiestrogen-treated ER+ express increased levels and are viable; (b) 4-OHT-induced death, but not...