A5008544250- Traditional Chinese Medicine Studies
- Traditional Chinese Medicine Analysis
- Healthcare and Venom Research
- Tryptophan and brain disorders
- Cardiac Imaging and Diagnostics
- Olfactory and Sensory Function Studies
- Acute Myocardial Infarction Research
- Plant-based Medicinal Research
- Stress Responses and Cortisol
- Circadian rhythm and melatonin
- Metabolomics and Mass Spectrometry Studies
- Lipid metabolism and disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Acupuncture Treatment Research Studies
- Asthma and respiratory diseases
- Polyomavirus and related diseases
- Sleep and Wakefulness Research
- Coronary Interventions and Diagnostics
- Cardiac Ischemia and Reperfusion
- Heart Rate Variability and Autonomic Control
- Hormonal Regulation and Hypertension
- Sepsis Diagnosis and Treatment
- Plant Virus Research Studies
- Regulation of Appetite and Obesity
- Chronic Kidney Disease and Diabetes
Guangdong Provincial Hospital of Traditional Chinese Medicine
2019-2025
Center for High Pressure Science & Technology Advanced Research
2022-2025
Guangzhou University of Chinese Medicine
2013-2025
Yunnan University of Traditional Chinese Medicine
2025
The Ohio State University Wexner Medical Center
2025
Taipei Medical University
2024
Yunnan University
2019-2024
Innovation Team (China)
2024
UConn Health
2017
Purdue University West Lafayette
2013
Ethnopharmacological relevance: Nasal administration was called nasal therapy in Chinese traditional medicine, which can be traced back to the Han dynasty (about 2000 years ago). Aromatherapy, predominantly employs essential oils (EOs), has emerged as a promising therapeutic modality field of drug delivery recent years. However, specific mechanisms by EOs access brain through route and impact mood regulation remain underexplored, greatly hinders promotion application aromatherapy. Cang-ai...
Background The efficacy and mechanism of Fufang Danshen dripping pills (FFDS) in the secondary prevention stable coronary heart disease (SCHD) is currently undetermined. This study aims to investigate preliminary by which FFDS may impact progression SCHD. Methods Based on randomization, we administered oral 30 patients with SCHD addition conventional treatment for days. After treatment, three-months major adverse cardiovascular events (MACE) were assessed as primary outcome. Additionally,...
Abstract Background We continue our exploration of the large polysaccharide polymer Chitosan as an acute therapy for severe damage to nervous system. tested action subcutaneously injected nanoparticles (~ 100 – 200 nanometers in diameter; 1 mg per ml) against control injections (silica particle same size and concentration) a standardized vivo spinal cord injury model. These functional tests used physiological measurements evoked potentials arriving at sensorimotor cortex subsequent...
This double-blind and randomized placebo-controlled trial evaluated the safety efficacy of Danhong injection combined with Naoxintong capsule in patients acute coronary syndrome (ACS) after percutaneous intervention (PCI).ACS scheduled to undergo PCI (n = 130) were equally randomly apportioned either a treatment or control group. After PCI, group received for 12 weeks, while was given placebo. Both groups otherwise treated conventional secondary prevention artery disease. The primarily...
We previously revealed that Cang-ai volatile oil (CAVO) regulates T-cell activity, enhancing the immune response in people with chronic respiratory diseases. However, effects of CAVO on allergic rhinitis (AR) have not been investigated. Herein, we established an ovalbumin (OVA)-induced AR rat model to determine these effects. Sprague–Dawley (SD) rats were exposed OVA for 3 weeks. or loratadine (positive control) was given orally once daily 2 weeks OVA-exposed rats. Behavior modeling nasal...
Pituitary tumors are frequently associated with mutations in the AIP gene and sometimes hypersecretion of growth hormone. It is unclear whether other factors besides an enlarged pituitary contribute to hypersecretion. In a genetic screen for suppressors reduced neurotransmitter release, we identified mutation Caenorhabditis elegans AIPR-1 (AIP-related-1), which causes profound increases evoked spontaneous high frequency calcium transients motor neurons readily releasable pool vesicles....
Abstract Background To assess the efficacy and safety of oral Guanxinshutong (GXST) capsules in Chinese patients with stable angina pectoris (SAP) a prospective, multicenter, double-Blind, placebo-controlled, randomized clinical trial ( clinicaltrials.gov Identifier: NCT02280850). Methods Eligible were 1:1 to GXST or placebo group. Current standard antianginal treatment except for nitrate drugs was continued both groups, who received an additional 4-week capsule placebo. Primary endpoint...
Abstract Background Coronary microvascular disease (CMVD) can be described as one of the cardiovascular diseases with normal coronary angiography but evidence myocardial ischemia or microcirculatory lesions, often presenting angina pectoris attacks. artery microtubular dysfunction is pathogenic features heart disease, its occurrence and development current CMVD-intervention therapy needs further research. Chinese traditional medicine (TCM) has advantages for treatment diseases. Hence, this...
Hyperactivity of the orexin system within paraventricular nucleus (PVN) has been shown to contribute increased sympathetic nerve activity (SNA) and blood pressure (BP) in rodent animals. However, underlying molecular mechanisms remain unclear. Here, we test hypothesis that activation stimulates calcium/calmodulin-dependent kinase II (CaMKII) expression activation, stimulation CaMKII expressing PVN neurons increases SNA BP. Real-time PCR and/or western blot were carried out effect orexin-A...
ABSTRACT Background and aims Rhynchophylline (RHY) can alleviate some cognitive flexibility impairment stereotyped behavior for attention‐deficit hyperactivity disorder (ADHD) Tourette syndrome (TS) patients as one of a key extract an active ingredient in Ningdong granule (NDG), which is Traditional Chinese medicine (TCM) preparation widely used the treatment ADHD TS children China; however, underlying mechanism not well understood. Therefore, this study aimed to evaluate how RHY alleviates...
Cang-Ai Volatile Oil (CAVO) is a traditional Chinese medicine prescription that can be used for improving depressive symptoms through the regulation of dopamine (DA) and 5-hydroxytryptamine (5-HT) inhibition inflammation. The purpose this study to verify whether CAVO has effects on depressed mood cortical excitability in human. Forty-six healthy individuals were enrolled instructed inhale month (five times per day). Each inhalation lasted at least one minute. Depressed was assessed using...