A5100369634- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac Valve Diseases and Treatments
- Lipoproteins and Cardiovascular Health
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Acute Kidney Injury Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Disease and Adiposity
- Peripheral Artery Disease Management
- Renal and Vascular Pathologies
- Chronic Kidney Disease and Diabetes
- Infectious Aortic and Vascular Conditions
- Diabetes Treatment and Management
- Acute Ischemic Stroke Management
- Trauma and Emergency Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Function and Risk Factors
- Hemostasis and retained surgical items
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Mechanical Circulatory Support Devices
General Hospital of Shenyang Military Region
2016-2025
Guangzhou University of Chinese Medicine
2025
Dalian Medical University
2014-2025
Cardiovascular Institute Hospital
2023-2024
China Medical University
2015-2024
Command Hospital
2021-2023
Jiaying University
2021-2023
Shenyang Pharmaceutical University
2022-2023
Creative Commons
2022
Second Affiliated Hospital of Xi'an Jiaotong University
2021
This study sought to evaluate the safety and efficacy of rosuvastatin in preventing contrast-induced acute kidney injury (CI-AKI) patients with diabetes mellitus (DM) chronic disease (CKD).CI-AKI is an important complication after contrast medium injection. While small studies have shown positive results statin therapy, role therapy prevention CI-AKI remains unknown.We randomized 2,998 type 2 DM concomitant CKD who were undergoing coronary/peripheral arterial angiography or without...
Limited evidence exists on the combined and mediating effects of systemic inflammation association between insulin resistance cardiovascular events in patients with diabetes chronic coronary syndrome (CCS). This secondary analysis a multicenter prospective cohort included 4419 diabetic CCS patients. Triglyceride–glucose index (TyG) high-sensitivity C-reactive protein (hsCRP) were applied to evaluate inflammation, respectively. The primary endpoint was major adverse cardiac event (MACE)....
Abdominal aortic aneurysm (AAA) is the most prevalent dilated arterial that poses a significant threat to older adults, but molecular mechanisms linking senescence AAA progression remain poorly understood. This study aims identify cellular senescence-related genes (SRGs) implicated in development and assess their potential as therapeutic targets. Four hundred twenty-nine differentially expressed (DEGs) were identified from GSE57691 training set, 867 SRGs obtained. Through intersection of...
This study aims to develop and validate a nomogram based on the Systemic Inflammatory Response Index (SIRI) predict short-term aortic-related adverse events (ARAEs) in patients with acute uncomplicated Type B intramural hematoma (IMH). We retrospectively analyzed 332 diagnosed IMH between April 2018 2024. Patients were categorized into stable group (N=225) exacerbation (N=107) occurrence of ARAEs within 30-day observation period. SIRI was calculated using neutrophil, monocyte, lymphocyte...
Abstract Background Stress hyperglycemia ratio (SHR), a novel biomarker of stress hyperglycemia, was proved to be reliable predictor short‐term adverse outcomes in patients with acute coronary syndromes (ACS). However, its impact on long‐term prognosis remained controversial. Methods A total 7662 ACS from large nationwide prospective cohort between January 2015 and May 2019 were included. SHR calculated by the following formula: = admission glucose (mmol/L)/(1.59 × HbA1c [%]−2.59). The...
Abstract Background The triglyceride–glucose (TyG) index and high‐sensitivity C‐reactive protein (hsCRP) are the commonly used biomarkers for insulin resistance systemic inflammation, respectively. We aimed to investigate combined association of TyG hsCRP with major adverse cardiovascular events (MACE) in patients chronic coronary syndrome (CCS). Methods A total 9421 CCS were included this study. primary endpoint was defined as a composite MACE covering all‐cause death, nonfatal myocardial...
To assess the immediate and long-term outcomes of transcatheter closure ventricular septal defect (VSD) in combination with percutaneous coronary intervention (PCI) patients VSD complicating acute myocardial infarction (AMI).Data were prospectively collected from 35 AMI who underwent attempted PCI therapy five high-volume heart centres. All survived procedures followed up by chest x-ray, electrocardiogram echocardiography. Thirteen urgent phase (within two weeks VSD) while others elective at...
Objective This study aimed to evaluate the impact of systemic inflammation burden using high-sensitivity C-reactive protein (hsCRP) and long-term prognosis in acute coronary syndrome (ACS) patients undergoing percutaneous intervention (PCI) stratified by bleeding risk status. Methods Consecutive admitted for ACS who received PCI between March 2016 2022 were enrolled analysis. Elevated was defined as hsCRP>2 mg/L, high (HBR) Academic Research Consortium (ARC)-HBR criteria. The primary...
Objective: To develop a nomogram based on the monocyte-to-lymphocyte ratio (MLR) for predicting risk of aortic-related adverse events within 30 days in patients with acute uncomplicated type B aortic intramural hematoma. Methods: This single-center retrospective cohort study screened consecutive hematoma treated at Emergency and Cardiovascular Medicine Departments General Hospital Northern Theater Command from April 2018 to 2024. Patients were divided into two groups optimal MLR cut-off...
Objective: To discuss the feasibility and safety of stage I anastomosis T-tube fistulation in laparoscopic local resection duodenal tumors. Methods: A descriptive case series study was used to retrospectively analyze clinical diagnosis treatment data 14 patients with tumors who successfully underwent + phase ostomy Guangdong Provincial Hospital Chinese Medicine First Affiliated Guangzhou University from October 2021 March 2024. The reconstruction steps tumor are as follows: (1) after safe...
We developed a risk stratification model to predict serious adverse hospitalization events (mortality, cardiac shock, arrest) (SAHE) after acute coronary syndrome (ACS) based on machine-learning models and logistic regression model. This cohort study is the CCC-ACS project. The primary efficacy outcomes were SAHE. Clinical prediction established five (XGBoost, RF, MLP, KNN, stacking model) models. Among 112 363 patients in study, age (55-65 years: OR: 1.392; 95%CI: 1.212-1.600; 65-75 1.878;...
Abstract Purpose Dual antiplatelet therapy (DAPT) is the cornerstone for patients with coronary atherosclerotic heart disease (CHD) undergoing percutaneous intervention (PCI) while increasing risk of bleeding, particularly when combined gastrointestinal (GID). Rivaroxaban 10 mg once daily widely used in Asia. This study compared effects low-dose rivaroxaban (10 daily) plus clopidogrel vs. DAPT CHD GID PCI. Methods In this prospective, single-center, randomized controlled trial, eligible PCI...
Elderly patients with coronary artery disease (CAD) are at heightened risk for ischemic and bleeding complications. This study evaluates antithrombotic therapy use its clinical outcomes in Chinese aged ≥65 years CAD elevated risk. prospective cohort enrolled diagnosed ≥ 1 high factor from two centers. We recorded major adverse cardiovascular events (MACE)-death, nonfatal myocardial infarction, stroke-and over a 2-year follow-up. Of 1005 (mean age 76.3 ± 7.2 years; 25.3% female), 49.0% were...
Whether percutaneous coronary intervention (PCI) can improve the long-term prognosis of patients with stable artery disease (SCAD) in comparison to conservative treatment remains controversial. The present study sought evaluate impacts initial invasive versus strategy on clinical outcomes for SCAD stratified by risk scores. This was a sub-analysis multicenter, observational Optimal antiPlatelet Therapy Chinese Coronary Artery Disease (OPT-CAD) study. Clinical were compared who initially...
Objective: To investigate the efficacy and safety of ablation index-guided radiofrequency catheter (RFCA) second-generation cryoballoon (CBA) in elderly patients with atrial fibrillation (AF). Methods: This retrospective cohort study included 1 986 undergoing pulmonary vein isolation for AF at General Hospital Northern Theater Command from August 2016 to May 2020, comprising 760 RFCA cases 226 CBA cases. Elderly were defined as those aged 60 years or older, while non-elderly under age. All...
The pH-sensitive fluorescent indicator 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein (BCECF) was used to measure lactate transport in single cardiac myocytes. Addition of externally caused a rapid fall intracellular pH (pHi), which largely inhibited by 5 mM alpha-cyano-4-hydroxycinnamate (CHC), specific inhibitor the carrier. Stilbene disulfonates such as 4,4'-dibenzamidostilbene-2,2'-disulfonate (DBDS) only partially response, with inhibition being greater guinea pig than rat data are...