A5091239998- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Sex work and related issues
- Diagnosis and treatment of tuberculosis
- COVID-19 epidemiological studies
- Global Maternal and Child Health
- SARS-CoV-2 detection and testing
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- HIV-related health complications and treatments
- Sexuality, Behavior, and Technology
- COVID-19 Pandemic Impacts
- Respiratory viral infections research
- Immune responses and vaccinations
- Infectious Diseases and Tuberculosis
- Child Nutrition and Water Access
- Biosensors and Analytical Detection
- HIV/AIDS Impact and Responses
- COVID-19 diagnosis using AI
- COVID-19 Clinical Research Studies
- COVID-19 Digital Contact Tracing
- Marine and coastal plant biology
National University of Singapore
2018-2025
National University Health System
2018-2025
The University of Sydney
2023-2025
Republic Polytechnic
2011
National University Hospital
2003-2006
Abstract We aimed to test the sensitivity of naso-oropharyngeal saliva and self-administered nasal (SN) swab compared nasopharyngeal (NP) for COVID-19 testing in a large cohort migrant workers Singapore. also tested utility next-generation sequencing (NGS) diagnosis COVID-19. Saliva, NP SN swabs were collected from subjects who presented with acute respiratory infection, their asymptomatic roommates, prior confirmed cases undergoing isolation at community care facility June 2020. All samples...
The Western Pacific Region has one of the fastest-growing populations older adults (≥ 65 years) globally, among whom tuberculosis (TB) poses a particular concern. This study reports country case studies from China, Japan, Republic Korea, and Singapore reflecting on their experiences in managing TB adults.Across all four countries, notification incidence rates were highest adults, but clinical public health guidance focused this population was limited. Individual illustrated range practices...
Panax notoginseng is a potential source of anticancer compounds. This study aims to investigate the effects steaming on chemical profile P. and anti-proliferative liver cancer cells.Samples powdered raw roots were steamed for various durations. Extracts samples subjected ultra-high pressure liquid chromatography/mass spectrometry (UHPLC-MS) analysis profiling. The three human cells, namely SNU449, SNU182 HepG2, evaluated using colorimetric WST-1 assay.Steaming changed chromatographic...
Objectives To develop a localised instrument and Bayesian statistical method to generate size estimates—adjusted for transmission error barrier effects—of at-risk populations in Singapore. Methods We conducted indepth interviews focus group guide the development of survey questionnaire. The questionnaire was administered between July August 2017 Using network scale-up (NSUM), we developed hierarchical model estimate number individuals four hidden at risk HIV. accounted both effects using...
Abstract Background Stigma is a significant barrier to healthcare and factor that drives the global burden of tuberculosis (TB). However, there scarcity information on TB stigma in developing countries. We aimed characterize, measure, explore determinants among people with Cambodia. Methods conducted mixed-methods study between February August 2019 using triangulation convergent design—a cross-sectional survey (n = 730) nested in-depth interviews 31) TB. Quantitative data were analyzed...
Abstract Background Cambodia is among the 30 countries in world with highest burden of tuberculosis (TB), and it estimated that 40% people TB remain undiagnosed. In this study, we aimed to investigate determinants delayed diagnosis treatment Cambodia. Methods This mixed-method explanatory sequential study was conducted between February September 2019 12 operational districts It comprised a retrospective cohort 721 TB, followed by series in-depth interviews. We assessed factors associated...
Understanding context-specific determinants of antiretroviral therapy (ART) adherence is crucial for developing tailored interventions improving health outcomes and achieving the UNAIDS' third 95% target. This cross-sectional study explores factors associated with ART among stable people living HIV on in Cambodia.We used baseline survey data from a quasi-experimental conducted 2021. The participants were recruited 20 clinics nine provinces face-to-face interviews. A structured questionnaire...
The Immunization Agenda 2030 emphasises the need for a motivated, skilled and knowledgeable workforce equipped to plan, manage, implement monitor immunisation programmes at all levels. rapid introduction of COVID-19 vaccines during pandemic highlighted adaptability health but also exposed gaps in professional development learning. This practice paper describes implementation an training programme Kingdom Cambodia Lao People’s Democratic Republic. was developed delivered by project team...
<title>Abstract</title> Cambodia’s HIV response successfully met the UNAIDS 90-90-90 targets in 2017; however, ongoing systemic barriers such as clinic congestion, stigma, and mental health disparities pose a threat to this progress. This quasi-experimental study evaluated community-based antiretroviral (ART) delivery (CAD) model against multi-month dispensing (MMD) for stable people living with from 2021 2023 across 20 ART clinics, enrolling total of 4,089 participants (2,040 CAD, 2,049...
Tuberculosis (TB) is an infectious disease closely intertwined with stigma, discrimination, and the social determinants of health. Communities people affected by TB are experts in their care pathways, but field continues to fall short meaningfully engaging communities research. This a missed opportunity improve quality, relevance, person-centeredness, positive impact, sustainability research outputs. We acknowledge important progress that has been made date regarding community engagement TB,...
Background: We studied humoral and cellular responses against SARS-CoV-2 longitudinally in a homogeneous population of healthy young/middle-aged men South Asian ethnicity with mild COVID-19. Methods: In total, we recruited 994 (median age: 34 years) post-COVID-19 diagnosis. Repeated cross-sectional surveys were conducted between May 2020 January 2021 at six time points – day 28 (n = 327), 80 202), 105 294), 140 172), 180 758), 280 311). Three commercial assays used to detect...
We report COVID-19 deaths by vaccine types (inactivated whole-virion SARS-CoV-2 [hereinafter inactivated vaccine], BNT162b2, and ChAdOx1 vaccines), vaccination status in Malaysia further stratified the analysis presence of comorbidities. used line list data on until 14 September 2021, made available publicly Ministry Health Malaysia.1Ministry MalaysiaOpen Malaysia.2021https://github.com/MoH-Malaysia/covid19-publicGoogle Scholar limited from 24 February 2021 onwards, after vaccines were...
Diagnosis and treatment of tuberculosis (TB) in children remain challenging, particularly resource-limited settings. Healthcare providers caregivers are critical improving childhood TB screening treatment. This study aimed to determine the barriers detection management from perspectives healthcare Cambodia.We conducted this qualitative between November December 2020. Data collection included in-depth interviews with 16 purposively selected four operational districts 28 close contact...
Abstract We evaluated the impact of coronavirus disease (COVID-19) on sex work industry and assessed how it has impacted health social conditions workers in Singapore. conducted a sequential exploratory mixed methods study amidst COVID-19 pandemic from April to October 2020, including in-depth interviews with 24 stakeholders surveyor-administered structured surveys 171 workers. had substantial workers' income. The illegality work, stigma, lack documentation were cited as exclusionary factors...
Background With support of the national tuberculosis (TB) program, KHANA (a local non-governmental organization in Cambodia) has implemented an innovative approach using a seed-and-recruit model to actively find TB cases community. The engaged community members including survivors as seed and newly diagnosed people with recruiters recruit presumptive their social network snowball for screening linkage treatment. This study aimed explore acceptability active case finding detecting new...
Retrofitting microhabitat features is a common ecological engineering technique for enhancing biodiversity and abundance of small, epilithic organisms on artificial shorelines by providing refuge spaces and/or ameliorating abiotic conditions. These are typically too small to be utilised as refugia larger, highly motile consumers such fish, but they may affect these through other mechanisms. This study sought determine whether enhancement units alter the fish abundance, richness assemblage...
Approximately 34% of people with tuberculosis (TB) were undiagnosed in Cambodia 2017. This study explored barriers access to TB services and information gaps by genders key populations the Cambodian national programme. In 2017, we conducted a consensus validation workshop, desk reviews, 19 in-depth interviews, 30 focus group discussions representatives stakeholder groups, affected populations, communities. Content analyses performed for qualitative interviews. We employed development methods...
Objectives Gay, bisexual and other men who have sex with (GBMSM) in Singapore may fear disclosing their sexual orientation to others due negative societal attitudes, the law that criminalises relations between men, which may, turn, impede access HIV/sexually transmitted infection (STI)-related health services. This study attempts determine how selective disclosure varying social groups, extent of disclosure, serve impact HIV/STI testing patterns among GBMSM. Methods In this observational...
The World Health Organization (WHO) estimated that 29% of global tuberculosis (TB) and almost 47% childhood TB cases were not reported to national programs in 2019. In Cambodia, most from health facilities supported by the Global Fund Fight AIDS, Tuberculosis, Malaria This study aimed compare healthcare providers' knowledge, attitude, practices (KAP) on case detection operational districts (ODs) with high low Cambodia.We conducted a cross-sectional between November December 2020 among...